Sampangine inhibits heme biosynthesis in both yeast and human.
about
Discovering thiamine transporters as targets of chloroquine using a novel functional genomics strategyIdentification of a New Class of Antifungals Targeting the Synthesis of Fungal Sphingolipids.Identification and characterization of haemofungin, a novel antifungal compound that inhibits the final step of haem biosynthesis.An extended set of yeast-based functional assays accurately identifies human disease mutations.Novel Agents and Drug Targets to Meet the Challenges of Resistant Fungi.Novel Cell-Killing Mechanisms of Hydroxyurea and the Implication Towards Combination Therapy for the Treatment of Fungal Infections.Increased heme synthesis in yeast induces a metabolic switch from fermentation to respiration even under conditions of glucose repression.New Horizons in Antifungal Therapy.Heme deficiency sensitizes yeast cells to oxidative stress induced by hydroxyurea.
P2860
Q21092414-4B834670-AB13-46BD-844E-971D558AC501Q35672458-FFE329CA-3E07-4CE0-A804-C5259DDCC267Q35889181-D238758F-9CDF-4C57-BDD7-23F4FCAA9538Q36893770-53A53A97-85CA-4110-ADB3-599447FE1FBEQ40045666-EB1CB1A8-0BEC-424A-BE5F-88CD965CE5B1Q40052683-22954EBD-5707-4A74-81CB-24FE296664E6Q47795404-733334C7-7E58-4F79-B6C7-CF8A1804A03DQ48149179-738934B8-45CC-4356-AF3E-7AB2E2390B21Q51071426-AB343F60-E6A2-480F-A049-E83D87364C67
P2860
Sampangine inhibits heme biosynthesis in both yeast and human.
description
2011 nî lūn-bûn
@nan
2011 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած
@hyw
2011 թվականի սեպտեմբերին հրատարակված գիտական հոդված
@hy
2011年の論文
@ja
2011年論文
@yue
2011年論文
@zh-hant
2011年論文
@zh-hk
2011年論文
@zh-mo
2011年論文
@zh-tw
2011年论文
@wuu
name
Sampangine inhibits heme biosynthesis in both yeast and human.
@ast
Sampangine inhibits heme biosynthesis in both yeast and human.
@en
type
label
Sampangine inhibits heme biosynthesis in both yeast and human.
@ast
Sampangine inhibits heme biosynthesis in both yeast and human.
@en
prefLabel
Sampangine inhibits heme biosynthesis in both yeast and human.
@ast
Sampangine inhibits heme biosynthesis in both yeast and human.
@en
P2093
P2860
P356
P1433
P1476
Sampangine inhibits heme biosynthesis in both yeast and human.
@en
P2093
Alice M Clark
Ameeta K Agarwal
Jianhuai Zhang
John D Phillips
Kaifu Chen
Xuewen Pan
Yongxiang Li
Zhiwei Huang
P2860
P304
P356
10.1128/EC.05170-11
P577
2011-09-09T00:00:00Z