C9orf72 promoter hypermethylation is neuroprotective: Neuroimaging and neuropathologic evidence.
about
There has been an awakening: Emerging mechanisms of C9orf72 mutations in FTD/ALSPhenotypic Heterogeneity of Monogenic Frontotemporal DementiaRNA metabolism in neurodegenerative disease.A C9ORF72 BAC mouse model recapitulates key epigenetic perturbations of ALS/FTDWhole-genome sequencing reveals important role for TBK1 and OPTN mutations in frontotemporal lobar degeneration without motor neuron disease.C9orf72 promoter hypermethylation is reduced while hydroxymethylation is acquired during reprogramming of ALS patient cells.Gain of Toxicity from ALS/FTD-Linked Repeat Expansions in C9ORF72 Is Alleviated by Antisense Oligonucleotides Targeting GGGGCC-Containing RNAsLongitudinal imaging in C9orf72 mutation carriers: Relationship to phenotype.Opening up the DNA methylome of dementiaInsights into the pathogenic mechanisms of Chromosome 9 open reading frame 72 (C9orf72) repeat expansions.ALS and FTD: an epigenetic perspective.Neuron loss and degeneration in the progression of TDP-43 in frontotemporal lobar degeneration.The C9orf72 repeat size correlates with onset age of disease, DNA methylation and transcriptional downregulation of the promoter.Cognitive reserve in frontotemporal degeneration: Neuroanatomic and neuropsychological evidence.A comparative bioinformatic analysis of C9orf72.
P2860
Q26750577-48EE10B8-83C8-49F3-AAE3-A0A32AFEF46BQ26782984-DE9C4C32-4318-42F9-910D-91D66F9FA74AQ33746283-AAF5E9A9-180F-4200-B763-C5EA4E63E616Q33791480-E350FAAE-9BD7-4745-B007-950C0F261783Q35752114-0D689925-AF51-4681-8A3F-CB4C06B368C4Q36600364-7D4DD050-8BC7-4F70-BD7B-F2D5AE17BC77Q36880235-C3B1E3DD-0B78-41B8-A846-3907298C1A4FQ37497445-34868540-F8DB-432B-B578-15C4DDD51240Q37736146-86B187D2-4031-4A34-89AA-91C52C2BE723Q38789426-0FBF6029-1B43-4042-998C-45C694280536Q38860456-04ABBD69-50E7-4987-9A68-7DE20FA3150BQ40055403-2FC9F486-78EC-44B8-BA1A-8DC34010E7CFQ40415783-1519CBEB-5BE1-4823-8C8C-9FBB789BA15FQ42727057-DE511431-3D7F-430D-AF90-5760F5333DC8Q50295667-99952157-C1A3-420F-B321-4C94D6503A8E
P2860
C9orf72 promoter hypermethylation is neuroprotective: Neuroimaging and neuropathologic evidence.
description
2015 nî lūn-bûn
@nan
2015 թուականի Մարտին հրատարակուած գիտական յօդուած
@hyw
2015 թվականի մարտին հրատարակված գիտական հոդված
@hy
2015年の論文
@ja
2015年論文
@yue
2015年論文
@zh-hant
2015年論文
@zh-hk
2015年論文
@zh-mo
2015年論文
@zh-tw
2015年论文
@wuu
name
C9orf72 promoter hypermethylat ...... and neuropathologic evidence.
@ast
C9orf72 promoter hypermethylat ...... and neuropathologic evidence.
@en
type
label
C9orf72 promoter hypermethylat ...... and neuropathologic evidence.
@ast
C9orf72 promoter hypermethylat ...... and neuropathologic evidence.
@en
prefLabel
C9orf72 promoter hypermethylat ...... and neuropathologic evidence.
@ast
C9orf72 promoter hypermethylat ...... and neuropathologic evidence.
@en
P2093
P2860
P1433
P1476
C9orf72 promoter hypermethylat ...... and neuropathologic evidence.
@en
P2093
David J Irwin
Edward B Lee
Elisabeth M Wood
Lauren Elman
Leo McCluskey
Murray Grossman
Vivanna Van Deerlin
P2860
P304
P356
10.1212/WNL.0000000000001495
P407
P577
2015-03-20T00:00:00Z