The course of Mycobacterium tuberculosis infection in the lungs of mice lacking expression of either perforin- or granzyme-mediated cytolytic mechanisms
about
Identification of murine H2-Dd- and H2-Ab-restricted T-cell epitopes on a novel protective antigen, MPT51, of Mycobacterium tuberculosis.Protection against Mycobacterium tuberculosis infection by CD8+ T cells requires the production of gamma interferon.Vaccination with plasmid DNA encoding mycobacterial antigen 85A stimulates a CD4+ and CD8+ T-cell epitopic repertoire broader than that stimulated by Mycobacterium tuberculosis H37Rv infectionFas (CD95)-dependent cell-mediated immunity to Listeria monocytogenes.High-frequency vaccine-induced CD8⁺ T cells specific for an epitope naturally processed during infection with Mycobacterium tuberculosis do not confer protectionHost defense against Mycobacterium avium does not have an absolute requirement for major histocompatibility complex class I-restricted T cells.Early emergence of CD8(+) T cells primed for production of type 1 cytokines in the lungs of Mycobacterium tuberculosis-infected mice.Identification and characterization of murine cytotoxic T cells that kill Mycobacterium tuberculosisHuman natural killer cells mediate killing of intracellular Mycobacterium tuberculosis H37Rv via granule-independent mechanisms.Tracking antigen-specific CD8 T lymphocytes in the lungs of mice vaccinated with the Mtb72F polyprotein.Altered CD8(+) T cell frequency and function in tuberculous lymphadenitis.The many faces of host responses to tuberculosis.Mycobacterium tuberculosis directs immunofocusing of CD8+ T cell responses despite vaccinationMycobacterium tuberculosis-specific CD8+ T cells require perforin to kill target cells and provide protection in vivo.Mycobacterium tuberculosis-specific CD8+ T cells and their role in immunity.Animal models of mycobacteria infection.Relative contributions of distinct MHC class I-dependent cell populations in protection to tuberculosis infection in mice.Gamma interferon responses of CD4 and CD8 T-cell subsets are quantitatively different and independent of each other during pulmonary Mycobacterium bovis BCG infectionGranzyme A Is Expressed in Mouse Lungs during Mycobacterium tuberculosis Infection but Does Not Contribute to Protection In VivoGranzyme B-expressing neutrophils correlate with bacterial load in granulomas from Mycobacterium tuberculosis-infected cynomolgus macaques.The tuberculous granuloma: an unsuccessful host defence mechanism providing a safety shelter for the bacteria?Impaired expression of perforin and granulysin in CD8+ T cells at the site of infection in human chronic pulmonary tuberculosis.Susceptibility of mice deficient in CD1D or TAP1 to infection with Mycobacterium tuberculosis.The relative importance of T cell subsets in immunity and immunopathology of airborne Mycobacterium tuberculosis infection in miceCytolytic CD8+ T cells recognizing CFP10 are recruited to the lung after Mycobacterium tuberculosis infection.CD40 ligand is not essential for induction of type 1 cytokine responses or protective immunity after primary or secondary infection with histoplasma capsulatum.Characterization of human CD8+ T cells reactive with Mycobacterium tuberculosis-infected antigen-presenting cells.Immune response to Mycobacterium tuberculosis and identification of molecular markers of disease.Antigen-specific CD8(+) T cells and protective immunity to tuberculosis.CD8 T cells and Mycobacterium tuberculosis infection.Accelerated induction of mycobacterial antigen-specific CD8+ T cells in the Mycobacterium tuberculosis-infected lung by subcutaneous vaccination with Mycobacterium bovis bacille Calmette-Guérin.Human CD8(+) T cells specific for Mycobacterium tuberculosis secreted antigens in tuberculosis patients and healthy BCG-vaccinated controls in The Gambia.Characterization of human Mycobacterium bovis bacille Calmette-Guérin-reactive CD8+ T cells.Immunization with heat-killed Mycobacterium vaccae stimulates CD8+ cytotoxic T cells specific for macrophages infected with Mycobacterium tuberculosis.Correlates of Vaccine-Induced Protection against Mycobacterium tuberculosis Revealed in Comparative Analyses of Lymphocyte Populations.Evidence for a perforin-mediated mechanism controlling cardiac inflammation in Trypanosoma cruzi infection.Expression of interferon-gamma and tumour necrosis factor-alpha messenger RNA does not correlate with protection in guinea pigs challenged with virulent Mycobacterium tuberculosis by the respiratory route.38 000 MW antigen-specific major histocompatibility complex class I restricted interferon-gamma-secreting CD8+ T cells in healthy contacts of tuberculosis.
P2860
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P2860
The course of Mycobacterium tuberculosis infection in the lungs of mice lacking expression of either perforin- or granzyme-mediated cytolytic mechanisms
description
1997 nî lūn-bûn
@nan
1997 թուականի Ապրիլին հրատարակուած գիտական յօդուած
@hyw
1997 թվականի ապրիլին հրատարակված գիտական հոդված
@hy
1997年の論文
@ja
1997年論文
@yue
1997年論文
@zh-hant
1997年論文
@zh-hk
1997年論文
@zh-mo
1997年論文
@zh-tw
1997年论文
@wuu
name
The course of Mycobacterium tu ...... -mediated cytolytic mechanisms
@ast
The course of Mycobacterium tu ...... -mediated cytolytic mechanisms
@en
type
label
The course of Mycobacterium tu ...... -mediated cytolytic mechanisms
@ast
The course of Mycobacterium tu ...... -mediated cytolytic mechanisms
@en
prefLabel
The course of Mycobacterium tu ...... -mediated cytolytic mechanisms
@ast
The course of Mycobacterium tu ...... -mediated cytolytic mechanisms
@en
P2093
P2860
P1476
The course of Mycobacterium tu ...... -mediated cytolytic mechanisms
@en
P2093
P2860
P304
P407
P577
1997-04-01T00:00:00Z