Crucial role for TNF receptor-associated factor 2 (TRAF2) in regulating NFκB2 signaling that contributes to autoimmunity - Wikidata - awgldk - TriplyDB

Crucial role for TNF receptor-associated factor 2 (TRAF2) in regulating NFκB2 signaling that contributes to autoimmunity

Crucial role for TNF receptor-associated factor 2 (TRAF2) in regulating NFκB2 signaling that contributes to autoimmunity

http://www.wikidata.org/entity/Q35546725

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Regulation of nuclear factor-κB in autoimmunity NF-κB Pathways in the Pathogenesis of Multiple Sclerosis and the Therapeutic Implications Tumor necrosis factor receptor-associated factor 2 mediates mitochondrial autophagy.Protein-Binding Function of RNA-Dependent Protein Kinase Promotes Proliferation through TRAF2/RIP1/NF-κB/c-Myc Pathway in Pancreatic β cells Targeting signaling factors for degradation, an emerging mechanism for TRAF functions Nemo-like kinase (NLK) negatively regulates NF-kappa B activity through disrupting the interaction of TAK1 with IKKβ.TNFR-associated factor 2 deficiency in B lymphocytes predisposes to chronic lymphocytic leukemia/small lymphocytic lymphoma in mice.TRAF2 regulates TNF and NF-κB signalling to suppress apoptosis and skin inflammation independently of Sphingosine kinase 1 A20: linking a complex regulator of ubiquitylation to immunity and human disease TRAF2 exerts opposing effects on basal and TNFα-induced activation of the classic IKK complex in hematopoietic cells in mice TRAF molecules in cell signaling and in human diseases The Src homology 3 domain-containing guanine nucleotide exchange factor is overexpressed in high-grade gliomas and promotes tumor necrosis factor-like weak inducer of apoptosis-fibroblast growth factor-inducible 14-induced cell migration and invasio Implications of Rho GTPase Signaling in Glioma Cell Invasion and Tumor Progression.The deubiquitinase A20 in immunopathology of autoimmune diseases.TNFR-Associated Factors 2 and 5 Differentially Regulate the Instructive IL-6 Receptor Signaling Required for Th17 Development.TRAF2 inhibits TRAIL- and CD95L-induced apoptosis and necroptosis.Constitutive expression of NF-κB inducing kinase in regulatory T cells impairs suppressive function and promotes instability and pro-inflammatory cytokine production.TRAF molecules in inflammation and inflammatory diseases.Role of PCSK9 in the Development of Mouse Periodontitis Before and After Treatment: A Double-Edged Sword.Role of TRAFs in Signaling Pathways Controlling T Follicular Helper Cell Differentiation and T Cell-Dependent Antibody Responses

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Crucial role for TNF receptor-associated factor 2 (TRAF2) in regulating NFκB2 signaling that contributes to autoimmunity

http://www.wikidata.org/entity/Q35546725

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2011 nî lūn-bûn

@nan

2011 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած

@hyw

2011 թվականի հոտեմբերին հրատարակված գիտական հոդված

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2011年の論文

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2011年論文

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2011年論文

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2011年論文

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2011年論文

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Crucial role for TNF receptor- ...... at contributes to autoimmunity

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Crucial role for TNF receptor- ...... at contributes to autoimmunity

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Crucial role for TNF receptor- ...... at contributes to autoimmunity

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Crucial role for TNF receptor- ...... at contributes to autoimmunity

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PNAS.1109427108

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Proceedings of the National Academy of Sciences of the United States of America

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Crucial role for TNF receptor- ...... at contributes to autoimmunity

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Anne Brüstle

http://www.w3.org/2001/XMLSchema#string

Iok In Christine Chio

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Nien-Jung Chen

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Tak Wah Mak

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Wanda Y Li

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Wen-Jye Lin

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Yong-Chen Lu

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Yu-Wen Su

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Zhenyue Hao

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P2860

The TRAF6 ubiquitin ligase and TAK1 kinase mediate IKK activation by BCL10 and MALT1 in T lymphocytes

Interleukin-21: Basic Biology and Implications for Cancer and Autoimmunity

IL-21 initiates an alternative pathway to induce proinflammatory T(H)17 cells

Early lethality, functional NF-kappaB activation, and increased sensitivity to TNF-induced cell death in TRAF2-deficient mice

Tumor necrosis factor receptor-associated factor 3 is a critical regulator of B cell homeostasis in secondary lymphoid organs

Rel induces interferon regulatory factor 4 (IRF-4) expression in lymphocytes: modulation of interferon-regulated gene expression by rel/nuclear factor kappaB.

IRF4 is essential for IL-21-mediated induction, amplification, and stabilization of the Th17 phenotype.

Constitutive production of NF-kappaB2 p52 is not tumorigenic but predisposes mice to inflammatory autoimmune disease by repressing Bim expression.

Noncanonical NF-kappaB activation requires coordinated assembly of a regulatory complex of the adaptors cIAP1, cIAP2, TRAF2 and TRAF3 and the kinase NIK.

TRAF2 and TRAF3 signal adapters act cooperatively to control the maturation and survival signals delivered to B cells by the BAFF receptor.

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