Tissue distribution and gender-divergent expression of 78 cytochrome P450 mRNAs in mice. - Wikidata - awgldk - TriplyDB

Tissue distribution and gender-divergent expression of 78 cytochrome P450 mRNAs in mice.

Tissue distribution and gender-divergent expression of 78 cytochrome P450 mRNAs in mice.

http://www.wikidata.org/entity/Q35551006

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An update on the role of intestinal cytochrome P450 enzymes in drug disposition Spaceflight Effects on Cytochrome P450 Content in Mouse Liver Cytochrome P450 1A2 Metabolizes 17β-Estradiol to Suppress Hepatocellular Carcinoma Hormonal regulation of Cyp4a isoforms in mouse liver and kidney.Zinc Fingers and Homeoboxes 2 (Zhx2) Regulates Sexually Dimorphic Cyp Gene Expression in the Adult Mouse Liver.Gender-Specific Effect of CYP2C8*3 on the Risk of Essential Hypertension in Bulgarian Patients.Hepatic metabolism affects the atropselective disposition of 2,2',3,3',6,6'-hexachlorobiphenyl (PCB 136) in mice.Male Sex is Associated with a Reduced Alveolar Epithelial Sodium Transport Relationship between Urinary N-Desmethyl-Acetamiprid and Typical Symptoms including Neurological Findings: A Prevalence Case-Control Study.Chiral polychlorinated biphenyls: absorption, metabolism and excretion--a review Ontogeny of novel cytochrome P450 gene isoforms during postnatal liver maturation in mice Developmental Regulation of Drug-Processing Genes in Livers of Germ-Free Mice RNA-Seq Quantification of Hepatic Drug Processing Genes in Germ-Free Mice.Dose of Phenobarbital and Age of Treatment at Early Life are Two Key Factors for the Persistent Induction of Cytochrome P450 Enzymes in Adult Mouse Liver Short-term calorie restriction feminizes the mRNA profiles of drug metabolizing enzymes and transporters in livers of mice.Compensatory changes in CYP expression in three different toxicology mouse models: CAR-null, Cyp3a-null, and Cyp2b9/10/13-null mice Metabolomic analysis and identification of a role for the orphan human cytochrome P450 2W1 in selective oxidation of lysophospholipids Hepatic Cyp2d and Cyp26a1 mRNAs and activities are increased during mouse pregnancy.RNA Sequencing Quantification of Xenobiotic-Processing Genes in Various Sections of the Intestine in Comparison to the Liver of Male Mice.Oral exposure to commercially available coal tar-based pavement sealcoat induces murine genetic damage and mutations.Cyp2c44 gene disruption exacerbated pulmonary hypertension and heart failure in female but not male mice Characterizing drug-metabolizing enzymes and transporters that are bona fide CAR-target genes in mouse intestine Cytochrome p450 mRNA expression in the rodent brain: species-, sex-, and region-dependent differences.Sex-dependent alteration of cardiac cytochrome P450 gene expression by doxorubicin in C57Bl/6 mice.A targeted proteomics approach for profiling murine cytochrome P450 expression.Ontogeny of mammalian metabolizing enzymes in humans and animals used in toxicological studies.Role of cytochrome P450-mediated arachidonic acid metabolites in the pathogenesis of cardiac hypertrophy.A mouse with humanized liver as an animal model for predicting drug effects and for studying hepatic viral infection: where to next?Extrahepatic metabolism at the body's internal-external interfaces.Potential of plant polyphenols to combat oxidative stress and inflammatory processes in farm animals.Empirical analysis of BMD metrics in genetic toxicology part II: in vivo potency comparisons to promote reductions in the use of experimental animals for genetic toxicity assessment.Sex differences in the circadian variation of cytochrome p450 genes and corresponding nuclear receptors in mouse liver.Nano-sized cytochrome P450 3A4 inhibitors to block hepatic metabolism of docetaxel.Tissue-specific in vivo genetic toxicity of nine polycyclic aromatic hydrocarbons assessed using the Muta™Mouse transgenic rodent assay.Daikenchuto (TU-100) alters murine hepatic and intestinal drug metabolizing enzymes in an in vivo dietary model: effects of gender and withdrawal Dose-response modeling of early molecular and cellular key events in the CAR-mediated hepatocarcinogenesis pathway.Relationship between tissue hydroxyl radical and oxidatively modified macromolecule levels.Evaluation of animal models for intestinal first-pass metabolism of drug candidates to be metabolized by CYP3A enzymes via in vivo and in vitro oxidation of midazolam and triazolam.Full Genome Survey and Dynamics of Gene Expression in the Greater Amberjack Seriola dumerili.Marmoset pulmonary cytochrome P450 2F1 oxidizes biphenyl and 7-ethoxycoumarin and hepatic human P450 substrates.

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P2860

Tissue distribution and gender-divergent expression of 78 cytochrome P450 mRNAs in mice.

http://www.wikidata.org/entity/Q35551006

description

2011 nî lūn-bûn

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2011 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած

@hyw

2011 թվականի սեպտեմբերին հրատարակված գիտական հոդված

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2011年の論文

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2011年論文

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2011年論文

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2011年論文

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2011年論文

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2011年論文

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2011年论文

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name

Tissue distribution and gender-divergent expression of 78 cytochrome P450 mRNAs in mice.

@ast

Tissue distribution and gender-divergent expression of 78 cytochrome P450 mRNAs in mice.

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type

label

Tissue distribution and gender-divergent expression of 78 cytochrome P450 mRNAs in mice.

@ast

Tissue distribution and gender-divergent expression of 78 cytochrome P450 mRNAs in mice.

@en

prefLabel

Tissue distribution and gender-divergent expression of 78 cytochrome P450 mRNAs in mice.

@ast

Tissue distribution and gender-divergent expression of 78 cytochrome P450 mRNAs in mice.

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Toxicological Sciences

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Tissue distribution and gender-divergent expression of 78 cytochrome P450 mRNAs in mice.

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Curtis D Klaassen

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Helen J Renaud

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Julia Yue Cui

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Mohammed Khan

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P2860

Initial sequencing and comparative analysis of the mouse genome

Comparison of cytochrome P450 (CYP) genes from the mouse and human genomes, including nomenclature recommendations for genes, pseudogenes and alternative-splice variants

Cloning, expression, and characterization of three new mouse cytochrome p450 enzymes and partial characterization of their fatty acid oxidation activities

Molecular cloning, enzymatic characterization, developmental expression, and cellular localization of a mouse cytochrome P450 highly expressed in kidney.

Cytochrome P450 CYP2J9, a new mouse arachidonic acid omega-1 hydroxylase predominantly expressed in brain.

Sexually dimorphic regulation and induction of P450s by the constitutive androstane receptor (CAR).

Gender-related differences in pharmacokinetics and their clinical significance.

Xenobiotic metabolism, genetic polymorphisms and male infertility.

Identification of a novel cytochrome P450, CYP4X1, with unique localization specific to the brain.

Sex is a major determinant of CYP3A4 expression in human liver.

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261-277

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2

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124

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