Development of gene-switch transgenic mice that inducibly express transforming growth factor beta1 in the epidermis. - Wikidata - awgldk - TriplyDB

Development of gene-switch transgenic mice that inducibly express transforming growth factor beta1 in the epidermis.

Development of gene-switch transgenic mice that inducibly express transforming growth factor beta1 in the epidermis.

http://www.wikidata.org/entity/Q35551846

about

TGF-β - an excellent servant but a bad master TGFβ Signaling in Tumor Initiation, Epithelial-to-Mesenchymal Transition, and Metastasis Healing of burn wounds in transgenic mice overexpressing transforming growth factor-beta 1 in the epidermis p63 is the molecular switch for initiation of an epithelial stratification program Nonviral gene transfer to skeletal, smooth, and cardiac muscle in living animals Myc regulates keratinocyte adhesion and differentiation via complex formation with Miz1 Loss of TGFbeta signaling destabilizes homeostasis and promotes squamous cell carcinomas in stratified epithelia.Distinct mechanisms of TGF-beta1-mediated epithelial-to-mesenchymal transition and metastasis during skin carcinogenesis.Conditional epidermal expression of TGFbeta 1 blocks neonatal lethality but causes a reversible hyperplasia and alopecia Advances in skin gene therapy.Mutant laboratory mice with abnormalities in hair follicle morphogenesis, cycling, and/or structure: annotated tables.Modeling cancer in mice.Of mice and models: improved animal models for biomedical research.Streptomyces-derived quorum-sensing systems engineered for adjustable transgene expression in mammalian cells and mice.Temporal smad7 transgene induction in mouse epidermis accelerates skin wound healing Progressive myopathy in an inducible mouse model of oculopharyngeal muscular dystrophy.Ligand-dependent genetic recombination in fibroblasts : a potentially powerful technique for investigating gene function in fibrosis Gene transfer in tissue repair: status, challenges and future directions.CtBP1 overexpression in keratinocytes perturbs skin homeostasis.WW Domain Containing Transcription Regulator regulates human conjunctiva epithelial cell proliferation via inhibiting TGFβ signaling pathway [corrected].Modelling cancer in human skin tissue.Genetically engineered mouse models in cancer research Gene therapy and wound healing Regulation of Skp2-p27 axis by the Cdh1/anaphase-promoting complex pathway in colorectal tumorigenesis.Prevention of trauma and hemorrhagic shock-mediated liver apoptosis by activation of stat3alpha.Functional conservation of Gsdma cluster genes specifically duplicated in the mouse genome.A genetic variant of Aurora kinase A promotes genomic instability leading to highly malignant skin tumors.Latent TGFbeta1 overexpression in keratinocytes results in a severe psoriasis-like skin disorder.TGF-β: duality of function between tumor prevention and carcinogenesis.Genetic approaches to study glial cells in the rodent brain.Genetic mouse models for skin research: strategies and resources.Pathway-specific profiling identifies the NF-kappa B-dependent tumor necrosis factor alpha-regulated genes in epidermal keratinocytes.Overexpression of Smad7 results in severe pathological alterations in multiple epithelial tissues.Expression of Gal4-dependent transgenes in cells of the mononuclear phagocyte system labeled with enhanced cyan fluorescent protein using Csf1r-Gal4VP16/UAS-ECFP double-transgenic mice.A robust, target-driven, cell-based assay for checkpoint kinase 1 inhibitors.Regulated and constitutive expression of anti-inflammatory cytokines by nontransforming herpesvirus saimiri vectors.Gas-inducible transgene expression in mammalian cells and mice.The Mad1 transcription factor is a novel target of activin and TGF-beta action in keratinocytes: possible role of Mad1 in wound repair and psoriasis.An in vivo study of Cdh1/APC in breast cancer formation.Evidence of EGR1 as a differentially expressed gene among proliferative skin diseases.

P2860

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P2860

Development of gene-switch transgenic mice that inducibly express transforming growth factor beta1 in the epidermis.

http://www.wikidata.org/entity/Q35551846

description

1999 nî lūn-bûn

@nan

1999 թուականի Յուլիսին հրատարակուած գիտական յօդուած

@hyw

1999 թվականի հուլիսին հրատարակված գիտական հոդված

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1999年の論文

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1999年論文

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1999年論文

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1999年論文

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1999年論文

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1999年論文

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1999年论文

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name

Development of gene-switch tra ...... factor beta1 in the epidermis.

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Development of gene-switch tra ...... factor beta1 in the epidermis.

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Development of gene-switch tra ...... factor beta1 in the epidermis.

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Development of gene-switch tra ...... factor beta1 in the epidermis.

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prefLabel

Development of gene-switch tra ...... factor beta1 in the epidermis.

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Development of gene-switch tra ...... factor beta1 in the epidermis.

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PNAS.96.15.8483

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Proceedings of the National Academy of Sciences of the United States of America

P1476

Development of gene-switch tra ...... factor beta1 in the epidermis.

@en

P2093

B W O'Malley

http://www.w3.org/2001/XMLSchema#string

D R Roop

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K M Liefer

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S Tsai

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X J Wang

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P2860

Transforming growth factor-beta: recent progress and new challenges.

Hepatic processing of transforming growth factor beta in the rat. Uptake, metabolism, and biliary excretion

A regulatory system for use in gene transfer.

Recombinant latent transforming growth factor beta 1 has a longer plasma half-life in rats than active transforming growth factor beta 1, and a different tissue distribution.

Expression of a dominant-negative type II transforming growth factor beta (TGF-beta) receptor in the epidermis of transgenic mice blocks TGF-beta-mediated growth inhibition.

TGF-beta: regulation of extracellular matrix.

Inhibition of skin development by overexpression of transforming growth factor beta 1 in the epidermis of transgenic mice

Loss of expression of transforming growth factor beta in skin and skin tumors is associated with hyperproliferation and a high risk for malignant conversion.

The proximal promoter of the mouse loricrin gene contains a functional AP-1 element and directs keratinocyte-specific but not differentiation-specific expression.

Regulation of endothelial cell growth, architecture, and matrix synthesis by TGF-beta.

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8483-8488

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15

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96

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12887367

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10411901

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17542

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