Knockdown of MADD and c-FLIP overcomes resistance to TRAIL-induced apoptosis in ovarian cancer cells. - Wikidata - awgldk - TriplyDB

Knockdown of MADD and c-FLIP overcomes resistance to TRAIL-induced apoptosis in ovarian cancer cells.

Knockdown of MADD and c-FLIP overcomes resistance to TRAIL-induced apoptosis in ovarian cancer cells.

http://www.wikidata.org/entity/Q35552511

about

MADD knock-down enhances doxorubicin and TRAIL induced apoptosis in breast cancer cells Cardanol isolated from Thai Apis mellifera propolis induces cell cycle arrest and apoptosis of BT-474 breast cancer cells via p21 upregulation Down-modulation of expression, or dephosphorylation, of IG20/MADD in tumor necrosis factor-related apoptosis-inducing ligand-resistant thyroid cancer cells makes them susceptible to treatment with this ligand.The pyrrolo-1,5-benzoxazepine, PBOX-15, enhances TRAIL‑induced apoptosis by upregulation of DR5 and downregulation of core cell survival proteins in acute lymphoblastic leukaemia cells.Targeting the metabolic pathway of human colon cancer overcomes resistance to TRAIL-induced apoptosis.IG20/MADD plays a critical role in glucose-induced insulin secretion.Alternative splicing as a biomarker and potential target for drug discovery.MADD is a downstream target of PTEN in triggering apoptosis.Nutlin-3 preferentially sensitises wild-type p53-expressing cancer cells to DR5-selective TRAIL over rhTRAIL.

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P2860

Knockdown of MADD and c-FLIP overcomes resistance to TRAIL-induced apoptosis in ovarian cancer cells.

http://www.wikidata.org/entity/Q35552511

description

2011 nî lūn-bûn

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2011 թուականի Մայիսին հրատարակուած գիտական յօդուած

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2011 թվականի մայիսին հրատարակված գիտական հոդված

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2011年の論文

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2011年論文

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2011年論文

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2011年論文

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2011年論文

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2011年論文

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2011年论文

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name

Knockdown of MADD and c-FLIP o ...... tosis in ovarian cancer cells.

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Knockdown of MADD and c-FLIP o ...... tosis in ovarian cancer cells.

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type

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Knockdown of MADD and c-FLIP o ...... tosis in ovarian cancer cells.

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Knockdown of MADD and c-FLIP o ...... tosis in ovarian cancer cells.

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Knockdown of MADD and c-FLIP o ...... tosis in ovarian cancer cells.

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Knockdown of MADD and c-FLIP o ...... tosis in ovarian cancer cells.

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J.AJOG.2011.05.035

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American Journal of Obstetrics and Gynecology

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Knockdown of MADD and c-FLIP o ...... tosis in ovarian cancer cells.

@en

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Ajay V Maker

http://www.w3.org/2001/XMLSchema#string

Bellur S Prabhakar

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Jacob Rotmensch

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Lakshmy Ganesh

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Liang-Cheng Li

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Lixia Qian

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Shankar Jayaram

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P2860

Contrasting effects of IG20 and its splice isoforms, MADD and DENN-SV, on tumor necrosis factor alpha-induced apoptosis and activation of caspase-8 and -3

Bid, a Bcl2 interacting protein, mediates cytochrome c release from mitochondria in response to activation of cell surface death receptors

Cleavage of BID by caspase 8 mediates the mitochondrial damage in the Fas pathway of apoptosis

DENN, a novel human gene differentially expressed in normal and neoplastic cells

Inhibition of death receptor signals by cellular FLIP

Identification and characterization of a new member of the TNF family that induces apoptosis

Induction of apoptosis by Apo-2 ligand, a new member of the tumor necrosis factor cytokine family

Cancer statistics, 2010

TRAIL receptor-2 signals apoptosis through FADD and caspase-8

IG20, in contrast to DENN-SV, (MADD splice variants) suppresses tumor cell survival, and enhances their susceptibility to apoptosis and cancer drugs

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362.e12-25

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10.1016/J.AJOG.2011.05.035

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