NATb/NAT1*4 promotes greater arylamine N-acetyltransferase 1 mediated DNA adducts and mutations than NATa/NAT1*4 following exposure to 4-aminobiphenyl

NATb/NAT1*4 promotes greater arylamine N-acetyltransferase 1 mediated DNA adducts and mutations than NATa/NAT1*4 following exposure to 4-aminobiphenyl

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http://www.wikidata.org/entity/Q35552622
Identification of cancer chemopreventive isothiocyanates as direct inhibitors of the arylamine N-acetyltransferase-dependent acetylation and bioactivation of aromatic amine carcinogensPhenotype of the most common "slow acetylator" arylamine N-acetyltransferase 1 genetic variant (NAT1*14B) is substrate-dependent.Functional analysis of arylamine N-acetyltransferase 1 (NAT1) NAT1*10 haplotypes in a complete NATb mRNA construct.Reduced 4-aminobiphenyl-induced liver tumorigenicity but not DNA damage in arylamine N-acetyltransferase null mice.Untargeted polar metabolomics of transformed MDA-MB-231 breast cancer cells expressing varying levels of human arylamine N-acetyltransferase 1.High N-acetyltransferase 1 (NAT1) expression is associated with estrogen receptor expression in breast tumors, but is not under direct regulation by estradiol, 17beta-diol, or dihydrotestosterone in breast cancer cells.Genetic and small molecule inhibition of arylamine N-acetyltransferase 1 reduces anchorage-independent growth in human breast cancer cell line MDA-MB-231.Retrospective analysis of estrogen receptor 1 and N‑acetyltransferase gene expression in normal breast tissue, primary breast tumors, and established breast cancer cell lines.
P2860

NATb/NAT1*4 promotes greater arylamine N-acetyltransferase 1 mediated DNA adducts and mutations than NATa/NAT1*4 following exposure to 4-aminobiphenyl

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http://www.wikidata.org/entity/Q35552622
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2011 nî lūn-bûn
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2011年の論文
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2011年論文
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2011年論文
@zh-hant
2011年論文
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2011年論文
@zh-mo
2011年論文
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2011年论文
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2011年论文
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2011年论文
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name
NATb/NAT1*4 promotes greater a ...... ng exposure to 4-aminobiphenyl
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NATb/NAT1*4 promotes greater a ...... ng exposure to 4-aminobiphenyl
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NATb/NAT1*4 promotes greater a ...... ng exposure to 4-aminobiphenyl
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NATb/NAT1*4 promotes greater a ...... ng exposure to 4-aminobiphenyl
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NATb/NAT1*4 promotes greater a ...... ng exposure to 4-aminobiphenyl
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NATb/NAT1*4 promotes greater a ...... ng exposure to 4-aminobiphenyl
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P1433
P1476
P2093
P2860
P304
P31
P356
P433
P478
P50
P577
P698
P932
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P1433
P1476
NATb/NAT1*4 promotes greater a ...... ng exposure to 4-aminobiphenyl
@en
P2093
P2860
P304
P31
P356
P433
P478
P50
P577
P698
P932