Shear stress-induced unfolding of VWF accelerates oxidation of key methionine residues in the A1A2A3 region.
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Evaluating the Atrial Myopathy Underlying Atrial Fibrillation: Identifying the Arrhythmogenic and Thrombogenic SubstrateRegulation of thrombosis and vascular function by protein methionine oxidationMethionine oxidation and reduction in proteinsHydrogen peroxide promotes aging-related platelet hyperactivation and thrombosisThe oxidative modification of von Willebrand factor is associated with thrombotic angiopathies in diabetes mellitusHypochlorous acid generated by neutrophils inactivates ADAMTS13: an oxidative mechanism for regulating ADAMTS13 proteolytic activity during inflammation.Hyperglycemia repression of miR-24 coordinately upregulates endothelial cell expression and secretion of von Willebrand factor.N-terminal flanking region of A1 domain in von Willebrand factor stabilizes structure of A1A2A3 complex and modulates platelet activation under shear stress.Inhibition of Hb Binding to GP1bα Abrogates Hb-Mediated Thrombus Formation on Immobilized VWF and Collagen under Physiological Shear StressFibrin clot structure and mechanics associated with specific oxidation of methionine residues in fibrinogen.Acquired von Willebrand syndrome associated with left ventricular assist device.A mechanism for localized dynamics-driven affinity regulation of the binding of von Willebrand factor to platelet glycoprotein Ibα.Development of a Functional Glomerulus at the Organ Level on a Chip to Mimic Hypertensive Nephropathy.Update on von Willebrand factor multimers: focus on high-molecular-weight multimers and their role in hemostasis.von Willebrand factor: at the crossroads of bleeding and thrombosis.Cardiovascular devices and platelet interactions: understanding the role of injury, flow, and cellular responses.von Willebrand factor: the old, the new and the unknown.On the versatility of von Willebrand factorPathophysiology of thrombotic thrombocytopenic purpura.Dynamics of von Willebrand factor reactivity in sickle cell disease during vaso-occlusive crisis and steady state.Methionine in Proteins: It's Not Just for Protein Initiation Anymore.The functions of the A1A2A3 domains in von Willebrand factor include multimerin 1 binding.Destabilization of the von Willebrand factor A2 domain under oxidizing conditions investigated by molecular dynamics simulations
P2860
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P2860
Shear stress-induced unfolding of VWF accelerates oxidation of key methionine residues in the A1A2A3 region.
description
2011 nî lūn-bûn
@nan
2011 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած
@hyw
2011 թվականի սեպտեմբերին հրատարակված գիտական հոդված
@hy
2011年の論文
@ja
2011年論文
@yue
2011年論文
@zh-hant
2011年論文
@zh-hk
2011年論文
@zh-mo
2011年論文
@zh-tw
2011年论文
@wuu
name
Shear stress-induced unfolding ...... residues in the A1A2A3 region.
@ast
Shear stress-induced unfolding ...... residues in the A1A2A3 region.
@en
type
label
Shear stress-induced unfolding ...... residues in the A1A2A3 region.
@ast
Shear stress-induced unfolding ...... residues in the A1A2A3 region.
@en
prefLabel
Shear stress-induced unfolding ...... residues in the A1A2A3 region.
@ast
Shear stress-induced unfolding ...... residues in the A1A2A3 region.
@en
P2093
P2860
P1433
P1476
Shear stress-induced unfolding ...... residues in the A1A2A3 region
@en
P2093
José A López
Junmei Chen
Ryan Gallagher
Xiaoyun Fu
Ying Zheng
P2860
P304
P356
10.1182/BLOOD-2011-01-331074
P407
P50
P577
2011-09-13T00:00:00Z