Estrogen receptor β represses Akt signaling in breast cancer cells via downregulation of HER2/HER3 and upregulation of PTEN: implications for tamoxifen sensitivity - Wikidata - awgldk - TriplyDB

Estrogen receptor β represses Akt signaling in breast cancer cells via downregulation of HER2/HER3 and upregulation of PTEN: implications for tamoxifen sensitivity

Estrogen receptor β represses Akt signaling in breast cancer cells via downregulation of HER2/HER3 and upregulation of PTEN: implications for tamoxifen sensitivity

http://www.wikidata.org/entity/Q35559028

about

Synergistic Anticancer Effect of Tocotrienol Combined with Chemotherapeutic Agents or Dietary Components: A Review Development of subtype-selective oestrogen receptor-based therapeutics.Estrogen inhibits renal cell carcinoma cell progression through estrogen receptor-β activation.MTDH mediates trastuzumab resistance in HER2 positive breast cancer by decreasing PTEN expression through an NFκB-dependent pathway Estrogen receptor alpha/beta ratio and estrogen receptor beta as predictors of endocrine therapy responsiveness-a randomized neoadjuvant trial comparison between anastrozole and tamoxifen for the treatment of postmenopausal breast cancer Pterostilbine, an active component of blueberries, sensitizes colon cancer cells to 5-fluorouracil cytotoxicity.Estrogen receptor α mediates proliferation of osteoblastic cells stimulated by estrogen and mechanical strain, but their acute down-regulation of the Wnt antagonist Sost is mediated by estrogen receptor β.Involvement of estrogen receptor β5 in the progression of glioma.Cell survival and metastasis regulation by Akt signaling in colorectal cancer Regulator of G protein signaling 6 is a novel suppressor of breast tumor initiation and progression Expressomal approach for comprehensive analysis and visualization of ligand sensitivities of xenoestrogen responsive genes.ERα and ERβ co-expression: An indicator of aggressive tumors and hormonal sensitivity.Estrogen receptor beta is involved in skeletal muscle hypertrophy induced by the phytoecdysteroid ecdysterone.Estrogen receptor beta (ERβ) produces autophagy and necroptosis in human seminoma cell line through the binding of the Sp1 on the phosphatase and tensin homolog deleted from chromosome 10 (PTEN) promoter gene.Prognostic and predictive value of ERβ1 and ERβ2 in the Intergroup Exemestane Study (IES)-first results from PathIES†.Identification of estrogen receptor β as a SUMO-1 target reveals a novel phosphorylated sumoylation motif and regulation by glycogen synthase kinase 3β.Targeting PES1 for restoring the ERα/ERβ ratio in breast cancer.Estrogen receptor β, a regulator of androgen receptor signaling in the mouse ventral prostate.Metformin Attenuates Testosterone-Induced Prostatic Hyperplasia in Rats: A Pharmacological Perspective.Update on the therapeutic significance of estrogen receptor beta in malignant gliomas.Estrogen receptor β regulates the tumoral suppressor PTEN to modulate pituitary cell growth.Membrane ERα attenuates myocardial fibrosis via RhoA/ROCK-mediated actin remodeling in ovariectomized female infarcted rats.Estrogen affects cell growth and IGF-1 receptor expression in renal cell carcinoma Cohort Profile: the Predictors of Breast Cancer Recurrence (ProBe CaRE) Premenopausal Breast Cancer Cohort Study in Denmark Endocrine Resistance in Breast Cancer

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P2860

Estrogen receptor β represses Akt signaling in breast cancer cells via downregulation of HER2/HER3 and upregulation of PTEN: implications for tamoxifen sensitivity

http://www.wikidata.org/entity/Q35559028

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2011 nî lūn-bûn

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Estrogen receptor β represses ...... ions for tamoxifen sensitivity

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Estrogen receptor β represses ...... ions for tamoxifen sensitivity

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Estrogen receptor β represses ...... ions for tamoxifen sensitivity

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Breast Cancer Research

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Estrogen receptor β represses ...... ions for tamoxifen sensitivity

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Jan-Åke Gustafsson

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Karolina Lindberg

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Lars-Arne Haldosén

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Yoko Omoto

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P2860

PTEN function: how normal cells control it and tumour cells lose it

Regulation of ERBB2 by oestrogen receptor-PAX2 determines response to tamoxifen

Escape from HER-family tyrosine kinase inhibitor therapy by the kinase-inactive HER3

Akt kinases in breast cancer and the results of adjuvant therapy

PIK3CA mutations correlate with hormone receptors, node metastasis, and ERBB2, and are mutually exclusive with PTEN loss in human breast carcinoma

Exploiting the PI3K/AKT pathway for cancer drug discovery

New insights into tumor suppression: PTEN suppresses tumor formation by restraining the phosphoinositide 3-kinase/AKT pathway

ERbeta in breast cancer--onlooker, passive player, or active protector?

Cytoplasmic localization of p21Cip1/WAF1 by Akt-induced phosphorylation in HER-2/neu-overexpressing cells.

Steroid hormone receptors in breast cancer management.

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10.1186/BCR2865

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