Arginine dependence of acute myeloid leukemia blast proliferation: a novel therapeutic target.
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Arginine Metabolism in Bacterial Pathogenesis and Cancer TherapyNovel immunotherapeutic approaches for the treatment of acute leukemia (myeloid and lymphoblastic)Growth suppressive effect of pegylated arginase in malignant pleural mesothelioma xenografts.L-Arginine supplementation inhibits the growth of breast cancer by enhancing innate and adaptive immune responses mediated by suppression of MDSCs in vivo.Collaborative Efforts Driving Progress in Pediatric Acute Myeloid Leukemia.Targeting cancer metabolism at the plasma membrane by limiting amino acid access through SLC6A14.RUNX1-Evi-1 fusion gene inhibited differentiation and apoptosis in myelopoiesis: an in vivo study.High Expression of CPT1A Predicts Adverse Outcomes: A Potential Therapeutic Target for Acute Myeloid Leukemia.IDENTIFYING CANCER SPECIFIC METABOLIC SIGNATURES USING CONSTRAINT-BASED MODELS.A novel and promising therapeutic approach for NSCLC: recombinant human arginase alone or combined with autophagy inhibitor.How does metabolism affect cell death in cancer?Drug-induced amino acid deprivation as strategy for cancer therapy.Blocking autophagy enhanced leukemia cell death induced by recombinant human arginase.Programmed cell death-1 pathway inhibition in myeloid malignancies: implications for myeloproliferative neoplasms.Insight on the impacts of free amino acids and their metabolites on the immune system from a perspective of inborn errors of amino acid metabolism.Development and evaluation of a host-targeted antiviral that abrogates herpes simplex virus replication through modulation of arginine-associated metabolic pathways.The creatine kinase pathway is a metabolic vulnerability in EVI1-positive acute myeloid leukemia.Hepatitis B virus X protein-induced upregulation of CAT-1 stimulates proliferation and inhibits apoptosis in hepatocellular carcinoma cells.Arginine auxotrophic gene signature in paediatric sarcomas and brain tumours provides a viable target for arginine depletion therapies.The arginine metabolome in acute lymphoblastic leukemia can be targeted by the pegylated-recombinant arginase I BCT-100.MUC1-mediated induction of myeloid-derived suppressor cells in patients with acute myeloid leukemia.Metabolic therapy with PEG-arginase induces a sustained complete remission in immunotherapy-resistant melanoma.Arginase 1 promotes retinal neurovascular protection from ischemia through suppression of macrophage inflammatory responsesRecombinant human arginase induces apoptosis through oxidative stress and cell cycle arrest in small cell lung cancerSensitivity of Colorectal Cancer to Arginine Deprivation Therapy is Shaped by Differential Expression of Urea Cycle Enzymes
P2860
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P2860
Arginine dependence of acute myeloid leukemia blast proliferation: a novel therapeutic target.
description
2015 nî lūn-bûn
@nan
2015年の論文
@ja
2015年論文
@yue
2015年論文
@zh-hant
2015年論文
@zh-hk
2015年論文
@zh-mo
2015年論文
@zh-tw
2015年论文
@wuu
2015年论文
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2015年论文
@zh-cn
name
Arginine dependence of acute m ...... n: a novel therapeutic target.
@ast
Arginine dependence of acute m ...... n: a novel therapeutic target.
@en
type
label
Arginine dependence of acute m ...... n: a novel therapeutic target.
@ast
Arginine dependence of acute m ...... n: a novel therapeutic target.
@en
prefLabel
Arginine dependence of acute m ...... n: a novel therapeutic target.
@ast
Arginine dependence of acute m ...... n: a novel therapeutic target.
@en
P2093
P2860
P50
P1433
P1476
Arginine dependence of acute m ...... on: a novel therapeutic target
@en
P2093
Carmela De Santo
Elena Odintsova
Joseph Higginbotham-Jones
Justin Loke
Kin Pong U
Margaret Ng
Pamela Kearns
Paul Cheng
Tracey Perry
P2860
P304
P356
10.1182/BLOOD-2014-09-600643
P407
P577
2015-02-20T00:00:00Z