Regulatory Role of Voltage-Gated Na Channel β Subunits in Sensory Neurons
about
Structure and function of μ-conotoxins, peptide-based sodium channel blockers with analgesic activityTetrodotoxin (TTX) as a therapeutic agent for pain.The β1-subunit of Na(v)1.5 cardiac sodium channel is required for a dominant negative effect through α-α interaction.Navβ4 regulates fast resurgent sodium currents and excitability in sensory neuronsThe immunoglobulin domain of the sodium channel β3 subunit contains a surface-localized disulfide bond that is required for homophilic bindingCo-expression of Na(V)β subunits alters the kinetics of inhibition of voltage-gated sodium channels by pore-blocking μ-conotoxins.Pharmacological fractionation of tetrodotoxin-sensitive sodium currents in rat dorsal root ganglion neurons by μ-conotoxinsA disulfide tether stabilizes the block of sodium channels by the conotoxin μO§-GVIIJ.A new look at sodium channel β subunitsRecent advances in voltage-gated sodium channels, their pharmacology, and related diseases.µ-Conotoxins Modulating Sodium Currents in Pain Perception and Transmission: A Therapeutic Potential.Distribution and function of voltage-gated sodium channels in the nervous system.
P2860
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P2860
Regulatory Role of Voltage-Gated Na Channel β Subunits in Sensory Neurons
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2011 nî lūn-bûn
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2011年の論文
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2011年論文
@yue
2011年論文
@zh-hant
2011年論文
@zh-hk
2011年論文
@zh-mo
2011年論文
@zh-tw
2011年论文
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2011年论文
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2011年论文
@zh-cn
name
Regulatory Role of Voltage-Gated Na Channel β Subunits in Sensory Neurons
@ast
Regulatory Role of Voltage-Gated Na Channel β Subunits in Sensory Neurons
@en
type
label
Regulatory Role of Voltage-Gated Na Channel β Subunits in Sensory Neurons
@ast
Regulatory Role of Voltage-Gated Na Channel β Subunits in Sensory Neurons
@en
prefLabel
Regulatory Role of Voltage-Gated Na Channel β Subunits in Sensory Neurons
@ast
Regulatory Role of Voltage-Gated Na Channel β Subunits in Sensory Neurons
@en
P2860
P356
P1476
Regulatory Role of Voltage-Gated Na Channel β Subunits in Sensory Neurons
@en
P2093
Michael E O'Leary
Mohamed Chahine
P2860
P356
10.3389/FPHAR.2011.00070
P577
2011-11-21T00:00:00Z