A gene expression signature from human breast cancer cells with acquired hormone independence identifies MYC as a mediator of antiestrogen resistance
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New and emerging factors in tumorigenesis: an overviewApplication of metabolomics in drug resistant breast cancer researchInduction of stable drug resistance in human breast cancer cells using a combinatorial zinc finger transcription factor libraryEpigenetic activation of the prostaglandin receptor EP4 promotes resistance to endocrine therapy for breast cancerKinesin family deregulation coordinated by bromodomain protein ANCCA and histone methyltransferase MLL for breast cancer cell growth, survival, and tamoxifen resistance.MYC regulates the unfolded protein response and glucose and glutamine uptake in endocrine resistant breast cancer.Cohesin is required for activation of MYC by estradiol.Global characterization of signalling networks associated with tamoxifen resistance in breast cancer.Loss of estrogen-regulated microRNA expression increases HER2 signaling and is prognostic of poor outcome in luminal breast cancer.MicroRNA-320a sensitizes tamoxifen-resistant breast cancer cells to tamoxifen by targeting ARPP-19 and ERRγCombined histone deacetylase inhibition and tamoxifen induces apoptosis in tamoxifen-resistant breast cancer models, by reversing Bcl-2 overexpressionCross-talk between ER and HER2 regulates c-MYC-mediated glutamine metabolism in aromatase inhibitor resistant breast cancer cells.Resistance to everolimus driven by epigenetic regulation of MYC in ER+ breast cancers.Oestrogen receptor-co-factor-chromatin specificity in the transcriptional regulation of breast cancer.MYC is expressed in the stromal and epithelial cells of primary breast carcinoma and paired nodal metastases.Anti-estrogen resistance in breast cancer is induced by the tumor microenvironment and can be overcome by inhibiting mitochondrial function in epithelial cancer cells.Gene-expression signature functional annotation of breast cancer tumours in function of ageAnalysis of Paired Primary-Metastatic Hormone-Receptor Positive Breast Tumors (HRPBC) Uncovers Potential Novel Drivers of Hormonal ResistanceHOXB7 Is an ERα Cofactor in the Activation of HER2 and Multiple ER Target Genes Leading to Endocrine Resistance.Altered regulation of PDK4 expression promotes antiestrogen resistance in human breast cancer cellsProteomic signatures of acquired letrozole resistance in breast cancer: suppressed estrogen signaling and increased cell motility and invasiveness.Improving Pathological Assessment of Breast Cancer by Employing Array-Based Transcriptome Analysis.Tumor suppressor ING4 inhibits estrogen receptor activity in breast cancer cells.Cyclin dependent kinase-9 mediated transcriptional de-regulation of cMYC as a critical determinant of endocrine-therapy resistance in breast cancers.Defining the transcriptional and biological response to CDK4/6 inhibition in relation to ER+/HER2- breast cancer.Epigenetic modulation: a novel therapeutic target for overcoming hormonal therapy resistance.Drug resistance to targeted therapies: déjà vu all over againEffects of In Utero Exposure to Ethinyl Estradiol on Tamoxifen Resistance and Breast Cancer Recurrence in a Preclinical Model.Resistance to Targeted Therapies in Breast Cancer.Stat3 accelerates Myc induced tumor formation while reducing growth rate in a mouse model of breast cancer.Decidua mesenchymal stem cells migrated toward mammary tumors in vitro and in vivo affecting tumor growth and tumor development.MYC-Driven Pathways in Breast Cancer Subtypes.G0S2 represses PI3K/mTOR signaling and increases sensitivity to PI3K/mTOR pathway inhibitors in breast cancer.A relative ordering-based predictor for tamoxifen-treated estrogen receptor-positive breast cancer patients: multi-laboratory cohort validation.EGR1 regulates cellular metabolism and survival in endocrine resistant breast cancer.
P2860
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P2860
A gene expression signature from human breast cancer cells with acquired hormone independence identifies MYC as a mediator of antiestrogen resistance
description
2011 nî lūn-bûn
@nan
2011年の論文
@ja
2011年論文
@yue
2011年論文
@zh-hant
2011年論文
@zh-hk
2011年論文
@zh-mo
2011年論文
@zh-tw
2011年论文
@wuu
2011年论文
@zh
2011年论文
@zh-cn
name
A gene expression signature fr ...... tor of antiestrogen resistance
@ast
A gene expression signature fr ...... tor of antiestrogen resistance
@en
type
label
A gene expression signature fr ...... tor of antiestrogen resistance
@ast
A gene expression signature fr ...... tor of antiestrogen resistance
@en
prefLabel
A gene expression signature fr ...... tor of antiestrogen resistance
@ast
A gene expression signature fr ...... tor of antiestrogen resistance
@en
P2093
P2860
P1476
A gene expression signature fr ...... tor of antiestrogen resistance
@en
P2093
Ana M González-Angulo
Anita Dunbier
Carlos L Arteaga
Gordon B Mills
Helen Anderson
Todd W Miller
William R Miller
Zara Ghazoui
P2860
P304
P356
10.1158/1078-0432.CCR-10-2567
P407
P577
2011-02-23T00:00:00Z