Discovery of Intestinal Targeted TGR5 Agonists for the Treatment of Type 2 Diabetes.

Discovery of Intestinal Targeted TGR5 Agonists for the Treatment of Type 2 Diabetes.

Item
http://www.wikidata.org/entity/Q35566964
An Intestinal Microbiota-Farnesoid X Receptor Axis Modulates Metabolic Disease.Bile Acids Trigger GLP-1 Release Predominantly by Accessing Basolaterally Located G Protein-Coupled Bile Acid Receptors.Gastroduodenal mucosal defense mechanisms.Discovery of a Potent and Orally Efficacious TGR5 Receptor Agonist.Intestinally-targeted TGR5 agonists equipped with quaternary ammonium have an improved hypoglycemic effect and reduced gallbladder filling effect.OL3, a novel low-absorbed TGR5 agonist with reduced side effects, lowered blood glucose via dual actions on TGR5 activation and DPP-4 inhibition.G protein-coupled receptors as new therapeutic targets for type 2 diabetes.Investigational insulin secretagogues for type 2 diabetes.Highly Selective Dopamine D3 Receptor (D3R) Antagonists and Partial Agonists Based on Eticlopride and the D3R Crystal Structure: New Leads for Opioid Dependence Treatment.Bile acid metabolism in liver pathobiology.The current state of GPCR-based drug discovery to treat metabolic disease.Functions of the Gallbladder.Differential Response of Human Hepatocyte Chromatin to HDAC Inhibitors as a Function of Microenvironmental Glucose Level.Discovery of Orally Efficacious Tetrahydrobenzimidazoles as TGR5 Agonists for Type 2 Diabetes.Bile acid metabolism and signaling in liver disease and therapyDissecting the Physiology and Pathophysiology of Glucagon-Like Peptide-1
P2860

Discovery of Intestinal Targeted TGR5 Agonists for the Treatment of Type 2 Diabetes.

Item
http://www.wikidata.org/entity/Q35566964
description
2015 nî lūn-bûn
@nan
2015年の論文
@ja
2015年論文
@yue
2015年論文
@zh-hant
2015年論文
@zh-hk
2015年論文
@zh-mo
2015年論文
@zh-tw
2015年论文
@wuu
2015年论文
@zh
2015年论文
@zh-cn
name
Discovery of Intestinal Targeted TGR5 Agonists for the Treatment of Type 2 Diabetes.
@ast
Discovery of Intestinal Targeted TGR5 Agonists for the Treatment of Type 2 Diabetes.
@en
type
label
Discovery of Intestinal Targeted TGR5 Agonists for the Treatment of Type 2 Diabetes.
@ast
Discovery of Intestinal Targeted TGR5 Agonists for the Treatment of Type 2 Diabetes.
@en
prefLabel
Discovery of Intestinal Targeted TGR5 Agonists for the Treatment of Type 2 Diabetes.
@ast
Discovery of Intestinal Targeted TGR5 Agonists for the Treatment of Type 2 Diabetes.
@en
P1433
P1476
P2093
P304
P31
P356
P407
P433
P478
P577
P698
P921
P356
P1433
P1476
Discovery of Intestinal Targeted TGR5 Agonists for the Treatment of Type 2 Diabetes.
@en
P2093
P304
P31
P356
P407
P433
P478
P577
P698
P921