cDNA cloning and sequence and cDNA-directed expression of human P450 IIB1: identification of a normal and two variant cDNAs derived from the CYP2B locus on chromosome 19 and differential expression of the IIB mRNAs in human liver.
about
Presence of the CYP2B6 516G> T polymorphism, increased plasma Efavirenz concentrations and early neuropsychiatric side effects in South African HIV-infected patientsPredictive value of known and novel alleles of CYP2B6 for efavirenz plasma concentrations in HIV-infected individuals.Five of 12 forms of vaccinia virus-expressed human hepatic cytochrome P450 metabolically activate aflatoxin B1The role of CYP2B6 in human xenobiotic metabolism.CYP2B6: new insights into a historically overlooked cytochrome P450 isozymeHuman cytochromes P450: evolution and cDNA-directed expression.Characterization of CYP2B6 in a CYP2B6-humanized mouse model: inducibility in the liver by phenobarbital and dexamethasone and role in nicotine metabolism in vivoBaculovirus vectors: novel mammalian cell gene-delivery vehicles and their applications.Prevalence of CYP2B6 alleles in malaria-endemic populations of West Africa and Papua New GuineaPhenobarbital induction of cytochrome P-450 gene expression.Heparin-binding properties of selenium-containing thioredoxin reductase from HeLa cells and human lung adenocarcinoma cellsCytochromes P-450 in rats: structures, functions, properties and relevant human forms.The human hepatic cytochromes P450 involved in drug metabolism.Overview of the pharmacogenetics of HIV therapy.Pharmacogenetic markers of CYP2B6 associated with efavirenz plasma concentrations in HIV-1 infected Thai adults.Functional constraints on the constitutive androstane receptor inferred from human sequence variation and cross-species comparisons.Polymorphic CYP2B6: molecular mechanisms and emerging clinical significance.A new selenoprotein from human lung adenocarcinoma cells: purification, properties, and thioredoxin reductase activity.Metabolism of drugs of abuse by cytochromes P450.Role of human cytochromes P450 in the metabolic activation of chemical carcinogens and toxins.In vitro methods for assessing human hepatic drug metabolism: their use in drug development.Identification of the human cytochrome P450 enzymes involved in the in vitro metabolism of artemisininA cytochrome P4502B form is the major bioactivation enzyme for the pyrrolizidine alkaloid senecionine in guinea pig.Pharmacokinetic interaction between efavirenz and carbamazepine after multiple-dose administration in healthy subjects.Human liver microsomal diazepam metabolism using cDNA-expressed cytochrome P450s: role of CYP2B6, 2C19 and the 3A subfamily.Quantitative RT-PCR measurement of cytochromes p450 1A1, 1B1, and 2B7, microsomal epoxide hydrolase, and NADPH oxidoreductase expression in lung cells of smokers and nonsmokers.
P2860
Q21245026-887131BB-8524-4217-8F34-280FF59F16F3Q33269667-F887CDCF-1538-4FCF-83C2-DBD3953A91FAQ33645193-C8A598D7-ECF9-4D51-A82B-92D136B1B0A4Q33719834-611D0939-284D-4278-BD40-4E3C49DC4FA2Q34824471-9A7B40D8-6C3C-428C-9D83-7242121B6453Q34844146-3E992D44-54EB-49BE-8896-E9E7CE47433AQ34946016-4A75EF2E-9D51-4A57-96DF-1759B62EF3A1Q35058030-08799412-9E86-437F-8EC0-04F1A956090BQ35669950-8FDD1CD1-F7EA-4967-92AE-4E19DEBBA620Q35887158-D05A52A8-7B6D-4528-99B9-682FE4CF986CQ36179977-28AB23BD-1A57-4BDD-B9FF-F94BA4D5ADA4Q36255451-F0889ADD-8BBE-4705-8713-6EE94A59109FQ36258518-E28C6D24-2601-4251-A138-14BFB8F2D882Q36389312-F34F8D44-DF4D-44EA-B512-00E7A0945309Q36468146-342B86E3-BCEB-445F-9FB1-9B5E1F7AB860Q36474869-5C981469-0F69-443E-BA6A-6A50642796DCQ36885659-3610A7EF-4B5A-4881-A18B-E71FB87AD1F4Q37727463-CF24421A-39FA-4789-B5FE-1885BED84AD8Q37767446-0C3BDD91-9837-4383-BE74-2DB0733BFC14Q40700838-415C5B97-D5C9-466D-BDE8-0A7A0F4B9BD1Q40817420-60555D2C-6FA3-4D7B-B231-EDC78A36A0CBQ40914424-8A6A3946-C487-4896-A09C-4DCDE16934CFQ46408072-2087E9A2-BB3B-4C2B-902D-4048C7D9FAE5Q46562540-D75847F4-2B56-4902-89B0-621B21FF0D26Q51558252-D25A3B91-7151-42C1-9151-6ECE49C540ACQ53442125-27C0D460-AAEA-4EB6-8E24-2DC97F0BAD21
P2860
cDNA cloning and sequence and cDNA-directed expression of human P450 IIB1: identification of a normal and two variant cDNAs derived from the CYP2B locus on chromosome 19 and differential expression of the IIB mRNAs in human liver.
description
1989 nî lūn-bûn
@nan
1989年の論文
@ja
1989年論文
@yue
1989年論文
@zh-hant
1989年論文
@zh-hk
1989年論文
@zh-mo
1989年論文
@zh-tw
1989年论文
@wuu
1989年论文
@zh
1989年论文
@zh-cn
name
cDNA cloning and sequence and ...... the IIB mRNAs in human liver.
@ast
cDNA cloning and sequence and ...... the IIB mRNAs in human liver.
@en
type
label
cDNA cloning and sequence and ...... the IIB mRNAs in human liver.
@ast
cDNA cloning and sequence and ...... the IIB mRNAs in human liver.
@en
prefLabel
cDNA cloning and sequence and ...... the IIB mRNAs in human liver.
@ast
cDNA cloning and sequence and ...... the IIB mRNAs in human liver.
@en
P2093
P356
P1433
P1476
cDNA cloning and sequence and ...... the IIB mRNAs in human liver.
@en
P2093
Gelboin HV
Gonzalez FJ
McBride OW
Nhamburo PT
P304
P356
10.1021/BI00444A029
P407
P577
1989-09-01T00:00:00Z