Murine models of polycystic kidney disease: molecular and therapeutic insights.
about
Carboxy terminal tail of polycystin-1 regulates localization of TSC2 to repress mTORNEK8 mutations affect ciliary and centrosomal localization and may cause nephronophthisisThe RNA-binding protein bicaudal C regulates polycystin 2 in the kidney by antagonizing miR-17 activityPkd1 and Pkd2 are required for normal placental developmentCharacterization of the SAM domain of the PKD-related protein ANKS6 and its interaction with ANKS3Cystin localizes to primary cilia via membrane microdomains and a targeting motif.Loss of polycystin-1 or polycystin-2 results in dysregulated apolipoprotein expression in murine tissues via alterations in nuclear hormone receptorsLoss of PKD1 and loss of Bcl-2 elicit polycystic kidney disease through distinct mechanismsGlomerulocystic kidney disease in mice with a targeted inactivation of Wwtr1Polycystic disease caused by deficiency in xylosyltransferase 2, an initiating enzyme of glycosaminoglycan biosynthesisTAZ promotes PC2 degradation through a SCFbeta-Trcp E3 ligase complexAcceleration of polycystic kidney disease progression in cpk mice carrying a deletion in the homeodomain protein Cux1An ovine hepatorenal fibrocystic model of a Meckel-like syndrome associated with dysmorphic primary cilia and TMEM67 mutations.A mitotic transcriptional switch in polycystic kidney diseaseHepato-renal pathology in pkd2ws25/- mice, an animal model of autosomal dominant polycystic kidney diseaseReceptor protein tyrosine phosphatases are novel components of a polycystin complexNovel targets for the treatment of autosomal dominant polycystic kidney disease.Polycystic liver diseases.Autosomal recessive polycystic kidney disease epithelial cell model reveals multiple basolateral epidermal growth factor receptor sorting pathways.Activator of G protein signaling 3 promotes epithelial cell proliferation in PKD.Kidney: polycystic kidney disease.An incredible decade for the primary cilium: a look at a once-forgotten organelle.Galectin-3 associates with the primary cilium and modulates cyst growth in congenital polycystic kidney diseaseLoss of primary cilia upregulates renal hypertrophic signaling and promotes cystogenesis.BICC1 expression is elevated in depressed subjects and contributes to depressive behavior in rodents.Biliary dysgenesis in the PCK rat, an orthologous model of autosomal recessive polycystic kidney diseaseFibrosis and progression of autosomal dominant polycystic kidney disease (ADPKD).Expression of Nek1 during kidney development and cyst formation in multiple nephron segments in the Nek1-deficient kat2J mouse model of polycystic kidney diseaseRenal Tubular Cyst Formation in Newborn Rats Treated with p-Cumylphenol.Cilia-like structures and polycystin-1 in osteoblasts/osteocytes and associated abnormalities in skeletogenesis and Runx2 expression.Congenital hepatic fibrosis in autosomal recessive polycystic kidney disease.Magnetic resonance microscopy of renal and biliary abnormalities in excised tissues from a mouse model of autosomal recessive polycystic kidney diseaseCystic kidney diseases: all roads lead to the cilium.Inhibition of Aerobic Glycolysis Attenuates Disease Progression in Polycystic Kidney Disease.Mammalian kidney development: principles, progress, and projectionsXenopus Bicaudal-C is required for the differentiation of the amphibian pronephros.The cpk model of recessive PKD shows glutamine dependence associated with the production of the oncometabolite 2-hydroxyglutarate.Genetic interaction studies link autosomal dominant and recessive polycystic kidney disease in a common pathway.Planar cell polarity and a potential role for a Wnt morphogen gradient in stereociliary bundle orientation in the mammalian inner ear.The Caenorhabditis elegans nephrocystins act as global modifiers of cilium structure.
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Murine models of polycystic kidney disease: molecular and therapeutic insights.
description
2003 nî lūn-bûn
@nan
2003年の論文
@ja
2003年論文
@yue
2003年論文
@zh-hant
2003年論文
@zh-hk
2003年論文
@zh-mo
2003年論文
@zh-tw
2003年论文
@wuu
2003年论文
@zh
2003年论文
@zh-cn
name
Murine models of polycystic kidney disease: molecular and therapeutic insights.
@ast
Murine models of polycystic kidney disease: molecular and therapeutic insights.
@en
type
label
Murine models of polycystic kidney disease: molecular and therapeutic insights.
@ast
Murine models of polycystic kidney disease: molecular and therapeutic insights.
@en
prefLabel
Murine models of polycystic kidney disease: molecular and therapeutic insights.
@ast
Murine models of polycystic kidney disease: molecular and therapeutic insights.
@en
P2860
P1476
Murine models of polycystic kidney disease: molecular and therapeutic insights.
@en
P2093
Lisa M Guay-Woodford
P2860
P304
P356
10.1152/AJPRENAL.00195.2003
P577
2003-12-01T00:00:00Z