PTHrP drives breast tumor initiation, progression, and metastasis in mice and is a potential therapy target. - Wikidata - awgldk - TriplyDB

PTHrP drives breast tumor initiation, progression, and metastasis in mice and is a potential therapy target.

PTHrP drives breast tumor initiation, progression, and metastasis in mice and is a potential therapy target.

http://www.wikidata.org/entity/Q35578573

about

Role of Parathyroid Hormone-Related Protein Signaling in Chronic Pancreatitis Calcium-Sensing Receptor in Breast Physiology and Cancer Twenty-five years of PTHrP progress: from cancer hormone to multifunctional cytokine.Urothelial signaling.Acinar cell-specific knockout of the PTHrP gene decreases the proinflammatory and profibrotic responses in pancreatitis.Cyclic AMP enhances TGFβ responses of breast cancer cells by upregulating TGFβ receptor I expression.Runx2-Smad signaling impacts the progression of tumor-induced bone disease Epidermal growth-factor-induced transcript isoform variation drives mammary cell migration.Functional and molecular characterisation of EO771.LMB tumours, a new C57BL/6-mouse-derived model of spontaneously metastatic mammary cancer.The Wnt inhibitor dickkopf-1: a link between breast cancer and bone metastases.Co-expression of parathyroid hormone related protein and TGF-beta in breast cancer predicts poor survival outcome.Identification of independent association signals and putative functional variants for breast cancer risk through fine-scale mapping of the 12p11 locus.Parathyroid hormone-related protein: an update.PTHrP and breast cancer: more than hypercalcemia and bone metastases.The role of the bone microenvironment in skeletal metastasis.A national portfolio of bone oncology trials-The Canadian experience in 2012.The multifaceted actions of PTHrP in skeletal metastasis Curcuminoids block TGF-β signaling in human breast cancer cells and limit osteolysis in a murine model of breast cancer bone metastasis.Parathyroid Hormone-Related Protein Interacts With the Transforming Growth Factor-β/Bone Morphogenetic Protein-2/Gremlin Signaling Pathway to Regulate Proinflammatory and Profibrotic Mediators in Pancreatic Acinar and Stellate Cells.Global profiling of prolactin-modulated transcripts in breast cancer in vivo.Integrin β4 regulation of PTHrP underlies its contribution to mammary gland development.PTHrP expression in human MDA-MB-231 breast cancer cells is critical for tumor growth and survival and osteoblast inhibition.Breast cancer metastasis: issues for the personalization of its prevention and treatment.Cancer Diagnostics via Ultrasensitive Multiplexed Detection of Parathyroid Hormone-Related Peptides with a Microfluidic Immunoarray Enhancement of taxol, doxorubicin and zoledronate anti-proliferation action on triple-negative breast cancer cells by a PTHrP blocking monoclonal antibody Parathyroid hormone-related protein drives a CD11b+Gr1+ cell-mediated positive feedback loop to support prostate cancer growth.Induction of thermal and mechanical hypersensitivity by parathyroid hormone-related peptide through upregulation of TRPV1 function and trafficking.Skeletal metastasis: treatments, mouse models, and the Wnt signaling.Gpr132 sensing of lactate mediates tumor-macrophage interplay to promote breast cancer metastasis.Parathyroid Hormone-Related Protein, Its Regulation of Cartilage and Bone Development, and Role in Treating Bone Diseases.PTHrP attenuates osteoblast cell death and apoptosis induced by a novel class of anti-cancer agents.Involvement of ERK1/2, p38 MAPK, and PI3K/Akt signaling pathways in the regulation of cell cycle progression by PTHrP in colon adenocarcinoma cells.PTHrP produced by myeloma plasma cells regulates their survival and pro-osteoclast activity for bone disease progression.Calcium-Sensing Receptor Promotes Breast Cancer by Stimulating Intracrine Actions of Parathyroid Hormone-Related Protein.Chemistry as an expanding resource in protein science: fully synthetic and fully active human parathyroid hormone-related protein (1-141).Targeting the Metastatic Bone Microenvironment by MicroRNAs.PTH1R-CaSR Cross Talk: New Treatment Options for Breast Cancer Osteolytic Bone Metastases

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P2860

PTHrP drives breast tumor initiation, progression, and metastasis in mice and is a potential therapy target.

http://www.wikidata.org/entity/Q35578573

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PTHrP drives breast tumor init ...... is a potential therapy target.

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PTHrP drives breast tumor init ...... is a potential therapy target.

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PTHrP drives breast tumor init ...... is a potential therapy target.

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Andrew C Karaplis

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Anne Camirand

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Dao C Huang

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Jiarong Li

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Peter M Siegel

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Richard Kremer

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William J Muller

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Xian Fang Yang

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P2860

Involvement of chemokine receptors in breast cancer metastasis

Parathyroid hormone-related protein is required for tooth eruption

Rescue of the parathyroid hormone-related protein knockout mouse demonstrates that parathyroid hormone-related protein is essential for mammary gland development

Lethal skeletal dysplasia from targeted disruption of the parathyroid hormone-related peptide gene

Genes that mediate breast cancer metastasis to lung

A multigenic program mediating breast cancer metastasis to bone

Metastasis to bone: causes, consequences and therapeutic opportunities

Exploiting the PI3K/AKT pathway for cancer drug discovery

Induction of mammary tumors by expression of polyomavirus middle T oncogene: a transgenic mouse model for metastatic disease

Molecular characterization of the tumor microenvironment in breast cancer.

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