Promoting motions in enzyme catalysis probed by pressure studies of kinetic isotope effects
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The Use of Multiscale Molecular Simulations in Understanding a Relationship between the Structure and Function of Biological Systems of the Brain: The Application to Monoamine Oxidase EnzymesBiochemistry and theory of proton-coupled electron transferAlteration of citrine structure by hydrostatic pressure explains the accompanying spectral shiftEffects of the donor-acceptor distance and dynamics on hydride tunneling in the dihydrofolate reductase catalyzed reactionDoes the pressure dependence of kinetic isotope effects report usefully on dynamics in enzyme H-transfer reactions?Coupling of pressure-induced structural shifts to spectral changes in a yellow fluorescent proteinHydrogen tunneling links protein dynamics to enzyme catalysisEffect of osmolytes on protein dynamics in the lactate dehydrogenase-catalyzed reaction.Examining the case for the effect of barrier compression on tunneling, vibrationally enhanced catalysis, catalytic entropy and related issuesGood vibrations in enzyme-catalysed reactions.Taking Ockham's razor to enzyme dynamics and catalysis."Eppur si muove" (Yet it moves).Kinetic effects of increased proton transfer distance on proton-coupled oxidations of phenol-amines.The enzyme aromatic amine dehydrogenase induces a substrate conformation crucial for promoting vibration that significantly reduces the effective potential energy barrier to proton transfer.Kinetic isotope effects as a probe of hydrogen transfers to and from common enzymatic cofactorsProbing quantum and dynamic effects in concerted proton-electron transfer reactions of phenol-base compounds.Relationship of femtosecond-picosecond dynamics to enzyme-catalyzed H-transfer.A complete thermodynamic analysis of enzyme turnover links the free energy landscape to enzyme catalysis.Atom Tunneling in Chemistry.Energy landscapes and catalysis in nitric-oxide synthase.Hydrostatic Pressure Studies Distinguish Global from Local Protein Motions in C-H Activation by Soybean Lipoxygenase-1.The fluorescent monomeric protein Kusabira Orange. Pressure effect on its structure and stability.Barrier compression and its contribution to both classical and quantum mechanical aspects of enzyme catalysis.Hydrogen donor-acceptor fluctuations from kinetic isotope effects: a phenomenological model.Probing active site geometry using high pressure and secondary isotope effects in an enzyme-catalysed 'deep' H-tunnelling reactionFree-Energy Landscape and Proton Transfer Pathways in Oxidative Deamination by Methylamine Dehydrogenase.Wide-dynamic-range kinetic investigations of deep proton tunnelling in proteins.Chimeric Styrene Monooxygenase with Increased Efficiency in Asymmetric Biocatalytic Epoxidation.Change in heat capacity accurately predicts vibrational coupling in enzyme catalyzed reactions.Protein motions and dynamic effects in enzyme catalysis.Der Tunneleffekt von Atomen in der ChemieProton tunnelling and promoting vibrations during the oxidation of ascorbate by ferricyanide?
P2860
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P2860
Promoting motions in enzyme catalysis probed by pressure studies of kinetic isotope effects
description
2007 nî lūn-bûn
@nan
2007年の論文
@ja
2007年論文
@yue
2007年論文
@zh-hant
2007年論文
@zh-hk
2007年論文
@zh-mo
2007年論文
@zh-tw
2007年论文
@wuu
2007年论文
@zh
2007年论文
@zh-cn
name
Promoting motions in enzyme ca ...... ies of kinetic isotope effects
@ast
Promoting motions in enzyme ca ...... ies of kinetic isotope effects
@en
type
label
Promoting motions in enzyme ca ...... ies of kinetic isotope effects
@ast
Promoting motions in enzyme ca ...... ies of kinetic isotope effects
@en
prefLabel
Promoting motions in enzyme ca ...... ies of kinetic isotope effects
@ast
Promoting motions in enzyme ca ...... ies of kinetic isotope effects
@en
P2860
P356
P1476
Promoting motions in enzyme ca ...... ies of kinetic isotope effects
@en
P2093
Nigel S Scrutton
P2860
P304
P356
10.1073/PNAS.0608408104
P407
P577
2007-01-03T00:00:00Z