Targeting thrombin--rational drug design from natural mechanisms.
about
Tong-xin-luo capsule for patients with coronary heart disease after percutaneous coronary interventionTong-xin-luo capsule for patients with coronary heart disease after percutaneous coronary interventionDiscovery and characterization of an antibody directed against exosite I of thrombinInitiating and potentiating role of platelets in tissue factor-induced thrombin generation in the presence of plasma: subject-dependent variation in thrombogram characteristicsDabigatran etexilate: an oral direct thrombin inhibitor for prophylaxis and treatment of thromboembolic diseases.A blood meal-induced Ixodes scapularis tick saliva serpin inhibits trypsin and thrombin, and interferes with platelet aggregation and blood clotting.On scaffold hopping: challenges in the discovery of sulfated small molecules as mimetics of glycosaminoglycans.Positive cooperativity between the thrombin and bradykinin B2 receptors enhances arachidonic acid release.Potent direct inhibitors of factor Xa based on the tetrahydroisoquinoline scaffold.Dental management of patients taking novel oral anticoagulants (NOAs): Dabigatran.Looking at the proteases from a simple perspective.Development of on-line high performance liquid chromatography (HPLC)-biochemical detection methods as tools in the identification of bioactives.New oral anticoagulants: comparative pharmacology with vitamin K antagonists.Comparison of the phase III clinical trial designs of novel oral anticoagulants versus warfarin for the treatment of nonvalvular atrial fibrillation: implications for clinical practice.Highly efficient control of thrombin activity by multivalent nanoparticles.Production and Purification of Rabbit's Polyclonal Antibody Against Factor VIII.Comparative binding energy analysis for binding affinity and target selectivity prediction.The heparin binding properties of heparin cofactor II suggest an antithrombin-like activation mechanism.Crystal structure of anticoagulant thrombin variant E217K provides insights into thrombin allostery.Crystal structure of thrombin bound to heparin.Fluorescence Sensing Using DNA Aptamers in Cancer Research and Clinical Diagnostics.Thrombin Receptor Agonist Peptide-Induced Platelet Aggregation Is Reduced in Patients Receiving Dabigatran.
P2860
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P2860
Targeting thrombin--rational drug design from natural mechanisms.
description
2003 nî lūn-bûn
@nan
2003年の論文
@ja
2003年論文
@yue
2003年論文
@zh-hant
2003年論文
@zh-hk
2003年論文
@zh-mo
2003年論文
@zh-tw
2003年论文
@wuu
2003年论文
@zh
2003年论文
@zh-cn
name
Targeting thrombin--rational drug design from natural mechanisms.
@ast
Targeting thrombin--rational drug design from natural mechanisms.
@en
type
label
Targeting thrombin--rational drug design from natural mechanisms.
@ast
Targeting thrombin--rational drug design from natural mechanisms.
@en
prefLabel
Targeting thrombin--rational drug design from natural mechanisms.
@ast
Targeting thrombin--rational drug design from natural mechanisms.
@en
P1476
Targeting thrombin--rational drug design from natural mechanisms.
@en
P2093
James A Huntington
Trevor P Baglin
P304
P356
10.1016/J.TIPS.2003.09.002
P577
2003-11-01T00:00:00Z