NOTCH decoys that selectively block DLL/NOTCH or JAG/NOTCH disrupt angiogenesis by unique mechanisms to inhibit tumor growth.
about
Anti-angiogenic alternatives to VEGF blockadeNotch signaling in prostate cancer: refining a therapeutic opportunityNotch signaling deregulation in multiple myeloma: A rational molecular targetSelective regulation of Notch ligands during angiogenesis is mediated by vimentinBlockade of specific NOTCH ligands: a new promising approach in cancer therapyNotch suppresses angiogenesis and progression of hepatic metastasesJagged mediates differences in normal and tumor angiogenesis by affecting tip-stalk fate decision.Notch-Jagged signalling can give rise to clusters of cells exhibiting a hybrid epithelial/mesenchymal phenotype.Human Cord Blood-Derived CD133+/C-Kit+/Lin- Cells Have Bipotential Ability to Differentiate into Mesenchymal Stem Cells and Outgrowth Endothelial Cells.The effect of epigenetic silencing and TP53 mutation on the expression of DLL4 in human cancer stem disorderNotch, lipids, and endothelial cells.Splice Variants of the RTK Family: Their Role in Tumour Progression and Response to Targeted Therapy.Classical VEGF, Notch and Ang signalling in cancer angiogenesis, alternative approaches and future directions (Review).Developmental pathways associated with cancer metastasis: Notch, Wnt, and Hedgehog.γ-Secretase inhibitors in cancer clinical trials are pharmacologically and functionally distinct.In vitro modeling of endothelial interaction with macrophages and pericytes demonstrates Notch signaling function in the vascular microenvironment.Endothelial Jagged1 promotes solid tumor growth through both pro-angiogenic and angiocrine functions.Delta-Like Ligand 4-Notch Signaling in Macrophage Activation.New Directions in Anti-Angiogenic Therapy for Glioblastoma.Notch Signaling in Vascular Smooth Muscle Cells.Multiple myeloma cells modify VEGF/IL-6 levels and osteogenic potential of bone marrow stromal cells via Notch/miR-223.Role of Delta-like 4 in Jagged1-induced tumour angiogenesis and tumour growth.Current Challenges in Translating Tissue-Engineered Heart Valves.Dll4 and Notch signalling couples sprouting angiogenesis and artery formation.Identification of small molecules uncoupling the Notch::Jagged interaction through an integrated high-throughput screening.Notch Signaling in Development, Tissue Homeostasis, and Disease.Perspectives on the discovery of NOTCH2-specific inhibitors.The vascular delta-like ligand-4 (DLL4)-Notch4 signaling correlates with angiogenesis in primary glioblastoma: an immunohistochemical study.Spatial patterning of the Notch ligand Dll4 controls endothelial sprouting in vitro.NOTCH regulation of the endothelial cell phenotype.MPDZ promotes DLL4-induced Notch signaling during angiogenesis.The Notch Ligand Jagged1 Regulates the Osteoblastic Lineage by Maintaining the Osteoprogenitor Pool.Crosstalk between Notch, HIF-1α and GPER in Breast Cancer EMTCancer Cells Exploit Notch Signaling to Redefine a Supportive Cytokine Milieu
P2860
Q26775947-64415C80-91C8-4380-B0F0-37D0FA255A5BQ26777624-9FB584D2-D753-4935-9EF6-736DDAA79764Q26797283-624E94A4-DD03-4C6C-98EF-A21D932803C9Q33790752-900D2A20-A658-48FA-8B81-D8C2ECE666F9Q35125234-62555298-CFE2-4560-88A3-3ECAB02E5466Q35463593-A7CD1924-2448-4D5E-B876-A5E81525A2DFQ35895576-B695F6ED-F49E-4BCC-AC08-73C050B7EAFFQ36966739-1E95DCC6-E4F8-473A-86D6-38E3041B9253Q37547699-79B61114-1521-439C-AC72-49FE1A977484Q37665224-A069C9A1-CC12-4040-9387-D12065F4D7DFQ37684675-C412716E-8AA5-4269-95E1-5ACB15FFBE4AQ37690917-7A78769F-0B50-4B52-B084-1A17CB64C5B4Q38645097-3BF93C6F-A3C0-41A2-825C-4D6F2C7CFAFDQ38728565-B68B391A-146C-4A51-A7E3-1D94147B4D1AQ38766437-3C7127D9-2C46-4366-ADF5-A72637F1A4CCQ38787175-6562769A-FCC9-44E3-8C07-4021B63687C2Q38849027-8A933B43-DEE4-4FB5-A33F-60B03BB1CECFQ38937592-AEF06C97-B6FB-4074-BB67-25EDA5A76A0FQ39022941-8D30B7A0-14F5-4951-8E8B-EA9C9262BDC7Q39141059-D17F73B0-979F-4D1B-A367-459D96FC5684Q39881866-9E344047-DAD3-483A-B4F6-DDB51497CF5DQ41093114-A600F8BE-B040-4675-8B54-FEEF43AF1C3CQ41268405-F430D231-A466-4AC3-B6D3-D73D5D6DD924Q46340126-540D26EF-B245-4588-9973-56B4168D6434Q46365083-C4AC7C38-9B57-45E0-9947-4B498F6EECF4Q46795621-1D5B84E2-35A4-4CD1-9AD9-DFB030CB400DQ48113221-B7911119-C956-46E0-9DB2-D98593C3DBB5Q52147874-6A44D064-2555-4091-A00B-994BA795873DQ52311934-2C79071F-3708-4E3B-AE3D-117CF107A737Q52353052-B9457DAD-B624-4FB5-BB95-8CCB222A755DQ52721396-D0C063B8-7544-40F3-B5F0-525ADD4027AAQ52893619-95813EB2-DE29-4508-8217-3CCA2F2E3088Q57109688-13098EF1-BE9A-4C98-827F-8842D41C7F69Q58781616-32859114-57BC-45CA-985E-46F85E7A4B7C
P2860
NOTCH decoys that selectively block DLL/NOTCH or JAG/NOTCH disrupt angiogenesis by unique mechanisms to inhibit tumor growth.
description
2014 nî lūn-bûn
@nan
2014年の論文
@ja
2014年論文
@yue
2014年論文
@zh-hant
2014年論文
@zh-hk
2014年論文
@zh-mo
2014年論文
@zh-tw
2014年论文
@wuu
2014年论文
@zh
2014年论文
@zh-cn
name
NOTCH decoys that selectively ...... nisms to inhibit tumor growth.
@ast
NOTCH decoys that selectively ...... nisms to inhibit tumor growth.
@en
type
label
NOTCH decoys that selectively ...... nisms to inhibit tumor growth.
@ast
NOTCH decoys that selectively ...... nisms to inhibit tumor growth.
@en
prefLabel
NOTCH decoys that selectively ...... nisms to inhibit tumor growth.
@ast
NOTCH decoys that selectively ...... nisms to inhibit tumor growth.
@en
P2093
P2860
P1433
P1476
NOTCH decoys that selectively ...... nisms to inhibit tumor growth.
@en
P2093
Aino Murtomaki
Carrie J Shawber
Henar Cuervo
Ian W Tattersall
Jan Kitajewski
Natalie M Kofler
Paul E Rosenstiel
Reyhaan A Chaudhri
Thaned Kangsamaksin
P2860
P304
P356
10.1158/2159-8290.CD-14-0650
P577
2014-11-11T00:00:00Z