Thermodynamic coupling between activation and inactivation gating in potassium channels revealed by free energy molecular dynamics simulations.
about
Probing the energy landscape of activation gating of the bacterial potassium channel KcsAGating of Connexin Channels by transjunctional-voltage: Conformations and models of open and closed states.Modeling and simulation of ion channels.Quantitative analysis of the water occupancy around the selectivity filter of a K+ channel in different gating modes.Initial steps of inactivation at the K+ channel selectivity filterVoltage regulation of connexin channel conductance.Modulation of Closed-State Inactivation in Kv2.1/Kv6.4 Heterotetramers as Mechanism for 4-AP Induced Potentiation.Pore helix-S6 interactions are critical in governing current amplitudes of KCNQ3 K+ channels.C-type inactivation of voltage-gated K+ channels: pore constriction or dilation?New potential binding determinant for hERG channel inhibitors.Multi-ion free energy landscapes underscore the microscopic mechanism of ion selectivity in the KcsA channelRecovery from slow inactivation in K+ channels is controlled by water molecules.Transmembrane allosteric energetics characterization for strong coupling between proton and potassium ion binding in the KcsA channel.Probing the Effects of Gating on the Ion Occupancy of the K+ Channel Selectivity Filter Using Two-Dimensional Infrared SpectroscopyHysteresis of KcsA potassium channel's activation- deactivation gating is caused by structural changes at the channel's selectivity filter.Key role of segment IS4 in Cav1.2 inactivation: link between activation and inactivation.An improved method for the cost-effective expression and purification of large quantities of KcsA.The gating cycle of a K+ channel at atomic resolution.Chemical substitutions in the selectivity filter of potassium channels do not rule out constricted-like conformations for C-type inactivation.
P2860
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P2860
Thermodynamic coupling between activation and inactivation gating in potassium channels revealed by free energy molecular dynamics simulations.
description
2011 nî lūn-bûn
@nan
2011年の論文
@ja
2011年論文
@yue
2011年論文
@zh-hant
2011年論文
@zh-hk
2011年論文
@zh-mo
2011年論文
@zh-tw
2011年论文
@wuu
2011年论文
@zh
2011年论文
@zh-cn
name
Thermodynamic coupling between ...... olecular dynamics simulations.
@ast
Thermodynamic coupling between ...... olecular dynamics simulations.
@en
type
label
Thermodynamic coupling between ...... olecular dynamics simulations.
@ast
Thermodynamic coupling between ...... olecular dynamics simulations.
@en
prefLabel
Thermodynamic coupling between ...... olecular dynamics simulations.
@ast
Thermodynamic coupling between ...... olecular dynamics simulations.
@en
P2093
P2860
P356
P1476
Thermodynamic coupling between ...... olecular dynamics simulations.
@en
P2093
Albert C Pan
Benoît Roux
Eduardo Perozo
Luis G Cuello
P2860
P304
P356
10.1085/JGP.201110670
P577
2011-12-01T00:00:00Z