What is the role of beta-adrenergic signaling in heart failure?
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Mdm2 directs the ubiquitination of beta-arrestin-sequestered cAMP phosphodiesterase-4D5The Role of Oxygen Sensors, Hydroxylases, and HIF in Cardiac Function and DiseaseCardiac cAMP: production, hydrolysis, modulation and detectionImaging alterations of cardiomyocyte cAMP microdomains in diseaseSignaling effectors underlying pathologic growth and remodeling of the heartNew advances in beta-blocker therapy in heart failureTherapeutic potential of PDE modulation in treating heart diseaseTargeting the ubiquitin-proteasome system in heart disease: the basis for new therapeutic strategiesNovel receptor-derived cyclopeptides to treat heart failure caused by anti-β1-adrenoceptor antibodies in a human-analogous rat modelAdeno-associated virus-mediated gene therapy in cardiovascular diseaseTop-down quantitative proteomics identified phosphorylation of cardiac troponin I as a candidate biomarker for chronic heart failureMicroRNA-1 downregulation by propranolol in a rat model of myocardial infarction: a new mechanism for ischaemic cardioprotectionAdrenergic stress reveals septal hypertrophy and proteasome impairment in heterozygous Mybpc3-targeted knock-in miceMolecular targets in heart failure gene therapy: current controversies and translational perspectivesS100A1: a multifaceted therapeutic target in cardiovascular diseaseRegulation of phosphodiesterase 3 and inducible cAMP early repressor in the heartRemoval of the N-terminal extension of cardiac troponin I as a functional compensation for impaired myocardial beta-adrenergic signalingNovel role for p90 ribosomal S6 kinase in the regulation of cardiac myofilament phosphorylationAKAP79-mediated targeting of the cyclic AMP-dependent protein kinase to the beta1-adrenergic receptor promotes recycling and functional resensitization of the receptorAn antagonism between the AKT and beta-adrenergic signaling pathways mediated through their reciprocal effects on miR-199a-5pThe dietary compound curcumin inhibits p300 histone acetyltransferase activity and prevents heart failure in ratsMyocardial MiR-30 downregulation triggered by doxorubicin drives alterations in β-adrenergic signaling and enhances apoptosisAgonist-specific activation of the beta2-adrenoceptor/Gs-protein and beta2-adrenoceptor/Gi-protein pathway in adult rat ventricular cardiomyocytes.Modeling the effects of β1-adrenergic receptor blockers and polymorphisms on cardiac myocyte Ca2+ handling.Saturated high-fat diet-induced obesity increases adenylate cyclase of myocardial β-adrenergic system and does not compromise cardiac function.Recent advances in the discovery of small molecules targeting exchange proteins directly activated by cAMP (EPAC).Cardiac models in drug discovery and development: a review.GnRH induces the c-Fos gene via phosphorylation of SRF by the calcium/calmodulin kinase II pathwayComputational models reduce complexity and accelerate insight into cardiac signaling networksReal-time optical recording of beta1-adrenergic receptor activation reveals supersensitivity of the Arg389 variant to carvedilolChronic alcohol consumption from adolescence-to-adulthood in mice--hypothalamic gene expression changes in the dilated cardiomyopathy signaling pathway.Cardiac myocyte-secreted cAMP exerts paracrine action via adenosine receptor activation.Both ligand- and cell-specific parameters control ligand agonism in a kinetic model of g protein-coupled receptor signaling.Pivotal effects of phosphodiesterase inhibitors on myocyte contractility and viability in normal and ischemic hearts.FRET biosensor uncovers cAMP nano-domains at β-adrenergic targets that dictate precise tuning of cardiac contractility.Role and possible mechanisms of clenbuterol in enhancing reverse remodelling during mechanical unloading in murine heart failureT-tubule remodelling disturbs localized β2-adrenergic signalling in rat ventricular myocytes during the progression of heart failure.Phosphodiesterase 4D is required for beta2 adrenoceptor subtype-specific signaling in cardiac myocytesBenefit of physical fitness against inflammation in obesity: role of beta adrenergic receptors.Mechanisms of enhanced beta-adrenergic reserve from cardiac resynchronization therapy.
P2860
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P2860
What is the role of beta-adrenergic signaling in heart failure?
description
2003 nî lūn-bûn
@nan
2003年の論文
@ja
2003年論文
@yue
2003年論文
@zh-hant
2003年論文
@zh-hk
2003年論文
@zh-mo
2003年論文
@zh-tw
2003年论文
@wuu
2003年论文
@zh
2003年论文
@zh-cn
name
What is the role of beta-adrenergic signaling in heart failure?
@ast
What is the role of beta-adrenergic signaling in heart failure?
@en
type
label
What is the role of beta-adrenergic signaling in heart failure?
@ast
What is the role of beta-adrenergic signaling in heart failure?
@en
prefLabel
What is the role of beta-adrenergic signaling in heart failure?
@ast
What is the role of beta-adrenergic signaling in heart failure?
@en
P2093
P1433
P1476
What is the role of beta-adrenergic signaling in heart failure?
@en
P2093
Martin J Lohse
Stefan Engelhardt
Thomas Eschenhagen
P304
P356
10.1161/01.RES.0000102042.83024.CA
P577
2003-11-01T00:00:00Z