Potent urea and carbamate inhibitors of soluble epoxide hydrolases. - Wikidata - awgldk - TriplyDB

Potent urea and carbamate inhibitors of soluble epoxide hydrolases.

Potent urea and carbamate inhibitors of soluble epoxide hydrolases.

http://www.wikidata.org/entity/Q35586009

about

Identification and functional characterization of human soluble epoxide hydrolase genetic polymorphisms Toxicology in the fast lane: application of high-throughput bioassays to detect modulation of key enzymes and receptors In vitro biologic activities of the antimicrobials triclocarban, its analogs, and triclosan in bioassay screens: receptor-based bioassay screens Investigation of human exposure to triclocarban after showering and preliminary evaluation of its biological effects The soluble epoxide hydrolase encoded by EPXH2 is a bifunctional enzyme with novel lipid phosphate phosphatase activity Lipid sulfates and sulfonates are allosteric competitive inhibitors of the N-terminal phosphatase activity of the mammalian soluble epoxide hydrolase Soluble epoxide hydrolase as a therapeutic target for cardiovascular diseases Discovery of inhibitors of soluble epoxide hydrolase: a target with multiple potential therapeutic indications Impact of soluble epoxide hydrolase and epoxyeicosanoids on human health Evaluation of fish models of soluble epoxide hydrolase inhibition Detoxification of environmental mutagens and carcinogens: structure, mechanism, and evolution of liver epoxide hydrolase Binding of alkylurea inhibitors to epoxide hydrolase implicates active site tyrosines in substrate activation Inhibition of soluble epoxide hydrolase by fulvestrant and sulfoxides Optimized inhibitors of soluble epoxide hydrolase improve in vitro target residence time and in vivo efficacy Fragment Screening of Soluble Epoxide Hydrolase for Lead Generation-Structure-Based Hit Evaluation and Chemistry Exploration EET signaling in cancer Triclocarban enhances testosterone action: a new type of endocrine disruptor?Soluble epoxide hydrolase inhibitors and heart failure Rational Design of Potent and Selective Inhibitors of an Epoxide Hydrolase Virulence Factor from Pseudomonas aeruginosa Soluble epoxide hydrolase plays an essential role in angiotensin II-induced cardiac hypertrophy Soluble epoxide hydrolase expression in a porcine model of arteriovenous graft stenosis and anti-inflammatory effects of a soluble epoxide hydrolase inhibitor Pharmacokinetic optimization of four soluble epoxide hydrolase inhibitors for use in a murine model of inflammation Soluble epoxide hydrolase gene deletion attenuates renal injury and inflammation with DOCA-salt hypertension Inhibition of soluble epoxide hydrolase contributes to the anti-inflammatory effect of antimicrobial triclocarban in a murine model The 2014 Bernard B. Brodie award lecture-epoxide hydrolases: drug metabolism to therapeutics for chronic pain Development of an HTS assay for EPHX2 phosphatase activity and screening of nontargeted libraries Soluble epoxide hydrolase in atherosclerosis An immunoassay to evaluate human/environmental exposure to the antimicrobial triclocarban Epoxides and soluble epoxide hydrolase in cardiovascular physiology Pharmacokinetic screening of soluble epoxide hydrolase inhibitors in dogs Beneficial effects of soluble epoxide hydrolase inhibitors in myocardial infarction model: Insight gained using metabolomic approaches Potent natural soluble epoxide hydrolase inhibitors from Pentadiplandra brazzeana baillon: synthesis, quantification, and measurement of biological activities in vitro and in vivo Attenuation of tobacco smoke-induced lung inflammation by treatment with a soluble epoxide hydrolase inhibitor Development of a high-throughput screen for soluble epoxide hydrolase inhibition Brassica napus soluble epoxide hydrolase (BNSEH1).Fluorescent substrates for soluble epoxide hydrolase and application to inhibition studies.The 5-substituted piperazine as a novel secondary pharmacophore greatly improving the physical properties of urea-based inhibitors of soluble epoxide hydrolase EH3 (ABHD9): the first member of a new epoxide hydrolase family with high activity for fatty acid epoxides.Symmetric adamantyl-diureas as soluble epoxide hydrolase inhibitors.Inhibition of soluble epoxide hydrolase by trans-4- [4-(3-adamantan-1-yl-ureido)-cyclohexyloxy]-benzoic acid is protective against ischemia-reperfusion injury.

P2860

Q22254318-6EBF804A-DF0E-4356-9AC2-E017D3F4427E Q23911122-7AC30CD6-7AED-4AA6-A3CB-95469991BE17 Q23916239-340E23B1-1234-4040-BCB3-4BD4029D650E Q23918896-5B1994E3-2774-4547-9784-13122A6C8951 Q24294384-7C0AFF51-B14F-4DE6-83EF-465C8D8121DD Q24546215-E83D87A8-5ABC-46AA-871F-AD1C6D25D14A Q24597172-A0423B90-5D05-4DCA-9096-14B849A7BA6F Q24616753-21FEF493-D778-463A-881D-1050E61FBB29 Q24618018-57153318-19F5-4B39-982B-9A9CAECB5FD4 Q24812965-9A708F85-B9B5-40BB-8B9F-A6D892B03774 Q27619610-2DB30B2E-751A-48EA-9F79-B1EEEDDA5ABF Q27622060-02B36872-C175-427A-B638-8470FAF85DFD Q27678172-C59E67A9-288D-4297-BA1A-67B5362DB5FE Q27684895-899C5D9E-76D0-4914-834A-0A9466CF0B21 Q27703977-FDCC0B07-6888-4364-A7D0-90B6720FF77F Q28250730-3C8E213B-23F4-459D-8728-A116F4E0108A Q28259283-FBCCAD6A-DB79-402D-80C0-BF2761E20D18 Q28383423-D02EE6BE-B096-4F82-B606-0B660C5B63ED Q28384766-986B01F5-5B0F-43FA-BA83-0CEB78E3C4EF Q28387081-D9509194-C31A-4B5D-A716-0E07B2BE2CD5 Q28387686-3BE19D7F-8E86-4E27-B511-DFAC413257B3 Q28389323-F0672247-251D-439F-8D73-70873A84C43F Q28390972-12FFE345-438C-49B7-8B9D-3F68047DE0FD Q28391172-85277762-F52F-438C-918A-A4A617FD5ED2 Q28392416-80FB0940-91B4-43CE-8FE0-5BD19752465A Q28393751-D729A9E2-D97D-4BF5-A4E9-3D85760FE616 Q28395004-B749E68E-3181-4EF9-8A08-8F15D7C1B59C Q28395553-EE485D95-75D1-4487-9C55-E4270FD0FC1B Q28396313-50A1C0C1-A81E-4558-8620-0A5279178FFD Q28396888-A1144495-C5B0-4E6C-9569-66476A445923 Q28397084-56E0DD03-5DCA-4990-842C-91DD47F6E2D8 Q28543232-7A4DC262-B185-4A7D-8BC6-443E65E6658F Q28571602-07A50179-D822-41BF-B574-FC506F28B8C4 Q30816822-36782C35-E43A-4C37-BFA2-60A1F56F79DF Q33184938-539B7931-EBE1-41FF-82FD-ADB7999D3C3F Q33217361-A8151517-3352-40CB-B3F6-48E59B9AB8E3 Q33247246-B5F6DAEA-5BCF-41AC-A809-C2F402215232 Q33288850-DA12BB6E-966E-4091-99DA-E8A069F90C4D Q33605509-B975E3C9-BA24-4F22-BB8D-BA4C2FE73026 Q33665713-A1248A86-E487-4F82-9795-0AEA313CB81B

P2860

Potent urea and carbamate inhibitors of soluble epoxide hydrolases.

http://www.wikidata.org/entity/Q35586009

description

1999 nî lūn-bûn

@nan

1999年の論文

@ja

1999年論文

@yue

1999年論文

@zh-hant

1999年論文

@zh-hk

1999年論文

@zh-mo

1999年論文

@zh-tw

1999年论文

@wuu

1999年论文

@zh

1999年论文

@zh-cn

name

Potent urea and carbamate inhibitors of soluble epoxide hydrolases.

@ast

Potent urea and carbamate inhibitors of soluble epoxide hydrolases.

@en

type

label

Potent urea and carbamate inhibitors of soluble epoxide hydrolases.

@ast

Potent urea and carbamate inhibitors of soluble epoxide hydrolases.

@en

prefLabel

Potent urea and carbamate inhibitors of soluble epoxide hydrolases.

@ast

Potent urea and carbamate inhibitors of soluble epoxide hydrolases.

@en

P1433

Q35586009-2595149A-3A3E-4EC8-BF72-CD68C3F971BD

P1476

Q35586009-1C405370-C475-4C92-8959-68074A7358FB

P2093

Q35586009-00460619-6A2B-44E9-A2FD-B6EB52F2DFD0

Q35586009-091F491C-7439-4EAD-91D5-D4FBB24D7BEA

Q35586009-3170E784-B0C9-4DBD-8842-21D96DD20757

Q35586009-4881528D-6CA2-4352-BE60-8215FD3CC6F0

Q35586009-57CCE4C0-D958-444E-9757-5085E3412998

Q35586009-D6D4127B-690B-4CFA-BB74-BDA3958374FB

Q35586009-EA8C482A-75AA-4077-9E53-955BA41EAB3C

P2860

Q35586009-1AD25BDA-3AB8-466D-8E96-D4F0834541EA

Q35586009-1C0CC024-CF33-4E4A-9C5D-033537ABC052

Q35586009-2DB133DA-6284-4CC3-804A-0A45EC6B481A

Q35586009-2EAC65BA-89A6-4C99-8F87-F538FC63D9F4

Q35586009-3B9D971D-95A2-41C1-9616-88025C13D47E

Q35586009-603BDBB2-7DD4-4DE9-A3EF-29AE55521384

Q35586009-62D44686-791B-48C2-95CD-FA392CBC1FA5

Q35586009-71F29294-D9FB-4461-B4CA-724083A51A6E

Q35586009-727DC3B9-8D17-4ADF-A866-63B7FDE064C0

Q35586009-732DC3D9-F80B-43FE-8284-8C73C21DD2F5

P304

Q35586009-B6B8FF8D-949B-4C8F-AF48-E03F743F9BE7

P31

Q35586009-676E1F8B-58E0-4C6F-9B73-A5B123FB23C9

P356

Q35586009-9D1FC90F-479A-467E-AEB1-E8ACE8B6ADE6

P407

Q35586009-A0F58EE6-0ACE-4583-9FFC-15C2AD9B8EFC

P433

Q35586009-7FC6D0C6-49A6-4E2B-B146-DF28459547F9

P478

Q35586009-443602E1-C4BC-4DA7-8543-FA236A068EB0

P577

Q35586009-D728F5B4-61C0-4C9B-9265-D29F216BB3DC

P5875

Q35586009-D954B71F-2BDD-4319-BB05-8C025D77FEFC

P698

Q35586009-D8A6B51C-F1D4-4DE1-BF33-4833C46607A1

P932

Q35586009-12F7DEFF-3334-4D08-9C95-437D213000BB

P356

PNAS.96.16.8849

P1433

Proceedings of the National Academy of Sciences of the United States of America

P1476

Potent urea and carbamate inhibitors of soluble epoxide hydrolases.

@en

P2093

B D Hammock

http://www.w3.org/2001/XMLSchema#string

C Morisseau

http://www.w3.org/2001/XMLSchema#string

D Dowdy

http://www.w3.org/2001/XMLSchema#string

J F Greene

http://www.w3.org/2001/XMLSchema#string

J R Sanborn

http://www.w3.org/2001/XMLSchema#string

J Zheng

http://www.w3.org/2001/XMLSchema#string

M H Goodrow

http://www.w3.org/2001/XMLSchema#string

P2860

cDNA cloning and expression of a soluble epoxide hydrolase from human liver

The role of human glutathione transferases and epoxide hydrolases in the metabolism of xenobiotics

Inhibition of cytosolic epoxide hydrolase by trans-3-phenylglycidols.

Kinetic and chemical mechanism of epoxide hydrolase.

Mammalian epoxide hydrases: inducible enzymes catalysing the inactivation of carcinogenic and cytotoxic metabolites derived from aromatic and olefinic compounds.

Molecular cloning and expression of murine liver soluble epoxide hydrolase.

The modern version of adult respiratory distress syndrome.

Bioactivation of leukotoxins to their toxic diols by epoxide hydrolase.

Development of an in situ toxicity assay system using recombinant baculoviruses.

Expression and characterization of the recombinant juvenile hormone epoxide hydrolase (JHEH) from Manduca sexta.

P304

8849-8854

http://www.w3.org/2001/XMLSchema#string

P31

scholarly article

P356

10.1073/PNAS.96.16.8849

http://www.w3.org/2001/XMLSchema#string

P407

P433

16

http://www.w3.org/2001/XMLSchema#string

P478

96

http://www.w3.org/2001/XMLSchema#string

P577

1999-08-01T00:00:00Z

http://www.w3.org/2001/XMLSchema#dateTime

P5875

235608964

http://www.w3.org/2001/XMLSchema#string

P698

10430859

http://www.w3.org/2001/XMLSchema#string

P932

17696

http://www.w3.org/2001/XMLSchema#string