TGFbeta induces morphological and molecular changes similar to human anterior subcapsular cataract
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The specificity of the interaction between αB-crystallin and desmin filaments and its impact on filament aggregation and cell viability.Protein expression profiling of lens epithelial cells from Prdx6-depleted mice and their vulnerability to UV radiation exposureMatrix metalloproteinase inhibitors suppress transforming growth factor-beta-induced subcapsular cataract formation.Temporal changes in MMP mRNA expression in the lens epithelium during anterior subcapsular cataract formation.Lens-specific expression of TGF-beta induces anterior subcapsular cataract formation in the absence of Smad3Desmin aggregate formation by R120G alphaB-crystallin is caused by altered filament interactions and is dependent upon network status in cellsMorgagnian cataract resulting from a naturally occurring nonsense mutation elucidates a role of CPAMD8 in mammalian lens developmentDownregulation of transforming growth factor-β type II receptor prohibit epithelial-to-mesenchymal transition in lens epithelium.Pax6 regulates gene expression in the vertebrate lens through miR-204Myo/Nog cells: targets for preventing the accumulation of skeletal muscle-like cells in the human lens.Sprouty2 Suppresses Epithelial-Mesenchymal Transition of Human Lens Epithelial Cells through Blockade of Smad2 and ERK1/2 Pathways.Sprouty is a negative regulator of transforming growth factor β-induced epithelial-to-mesenchymal transition and cataract.Transforming growth factor-beta-induced epithelial-mesenchymal transition in the lens: a model for cataract formation.Fibrosis in the lens. Sprouty regulation of TGFβ-signaling prevents lens EMT leading to cataract.Crim1 regulates integrin signaling in murine lens development.Elevated tropomyosin expression is associated with epithelial-mesenchymal transition of lens epithelial cells.Nitric oxide, a survival factor for lens epithelial cells.Cell cycle regulation in the developing lens.Downregulation of MMP-2 and -9 by proteasome inhibition: a possible mechanism to decrease LEC migration and prevent posterior capsular opacificationGlutathione and catalase suppress TGFbeta-induced cataract-related changes in cultured rat lenses and lens epithelial explantsTGFbeta promotes Wnt expression during cataract developmentIntegrins in lens development and disease.Loss of NF-kappaB control and repression of Prdx6 gene transcription by reactive oxygen species-driven SMAD3-mediated transforming growth factor beta signalingRhoA/ROCK signaling regulates TGFβ-induced epithelial-mesenchymal transition of lens epithelial cells through MRTF-ATGF-β1 serum concentrations and receptor expressions in the lens capsular of dogs with diabetes mellitus.Bone Morphogenetic Protein-7 Suppresses TGFβ2-Induced Epithelial-Mesenchymal Transition in the Lens: Implications for Cataract Prevention.Development and use of the lens epithelial explant system to study lens differentiation and cataractogenesis.The roles of αV integrins in lens EMT and posterior capsular opacification.FGF2 antagonizes aberrant TGFβ regulation of tropomyosin: role for posterior capsule opacity.The lens as a model for fibrotic disease.ERK1/2 signaling is required for the initiation but not progression of TGFβ-induced lens epithelial to mesenchymal transition (EMT).Ganglioside GM3 participates in the TGF-β1-induced epithelial-mesenchymal transition of human lens epithelial cells.The murine lens: A model to investigate in vivo epithelial-mesenchymal transition.IGF-1 counteracts TGF-beta-mediated enhancement of fibronectin for in vitro human lens epithelial cells.TGF-beta-induced apoptosis and reduction of Bcl-2 in human lens epithelial cells in vitro.The role of Prdx6 in the protection of cells of the crystalline lens from oxidative stress induced by UV exposure.Association of histone acetylation at the ACTA2 promoter region with epithelial mesenchymal transition of lens epithelial cells.Induction of corneal myofibroblasts by lens-derived transforming growth factor beta1 (TGFbeta1): a transgenic mouse model.alpha-Smooth muscle actin is constitutively expressed in the lens epithelial cells of several species.Incidences and Range of Spontaneous Lesions in the Eye of Crl:CD-1(ICR)BR Mice Used in Toxicity Studies.
P2860
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P2860
TGFbeta induces morphological and molecular changes similar to human anterior subcapsular cataract
description
2002 nî lūn-bûn
@nan
2002年の論文
@ja
2002年論文
@yue
2002年論文
@zh-hant
2002年論文
@zh-hk
2002年論文
@zh-mo
2002年論文
@zh-tw
2002年论文
@wuu
2002年论文
@zh
2002年论文
@zh-cn
name
TGFbeta induces morphological ...... anterior subcapsular cataract
@ast
TGFbeta induces morphological ...... anterior subcapsular cataract
@en
type
label
TGFbeta induces morphological ...... anterior subcapsular cataract
@ast
TGFbeta induces morphological ...... anterior subcapsular cataract
@en
prefLabel
TGFbeta induces morphological ...... anterior subcapsular cataract
@ast
TGFbeta induces morphological ...... anterior subcapsular cataract
@en
P2093
P2860
P356
P1476
TGFbeta induces morphological ...... anterior subcapsular cataract
@en
P2093
Angela M Hales
Coral G Chamberlain
Frank J Lovicu
John W McAvoy
Lisa N Vincent
P2860
P304
P356
10.1136/BJO.86.2.220
P407
P577
2002-02-01T00:00:00Z