Biogenesis of the platelet receptor for fibrinogen: evidence for separate precursors for glycoproteins IIb and IIIa.
about
cDNA and amino acid sequences of the cell adhesion protein receptor recognizing vitronectin reveal a transmembrane domain and homologies with other adhesion protein receptorsComplete amino acid sequence of a human platelet proteoglycanThe GPIIb/IIIa (integrin alphaIIbbeta3) odyssey: a technology-driven saga of a receptor with twists, turns, and even a bend.Physical linkage of the genes for platelet membrane glycoproteins IIb and IIIa.Glanzmann thrombasthenia resulting from a single amino acid substitution between the second and third calcium-binding domains of GPIIb. Role of the GPIIb amino terminus in integrin subunit associationMolecular cloning and chemical synthesis of a region of platelet glycoprotein IIb involved in adhesive function.Glanzmann's thrombasthenia: an overview.Three novel beta-propeller mutations causing Glanzmann thrombasthenia result in production of normally stable pro-alphaIIb, but variably impaired progression of pro-alphaIIbbeta3 from endoplasmic reticulum to GolgiGray platelet syndrome. Demonstration of alpha granule membranes that can fuse with the cell surface.Platelet glycoprotein IIb. Chromosomal localization and tissue expression.Mapping early conformational changes in alphaIIb and beta3 during biogenesis reveals a potential mechanism for alphaIIbbeta3 adopting its bent conformation.Fibrinogen and glycoprotein IIb/IIIa localization during platelet adhesion. Localization to the granulomere and at sites of platelet interaction.The human platelet fibrinogen receptor: clinical and therapeutic significance.Adhesive properties of the beta 3 integrins: comparison of GP IIb-IIIa and the vitronectin receptor individually expressed in human melanoma cellsCoexpression of GMP-140 and PAF by endothelium stimulated by histamine or thrombin: a juxtacrine system for adhesion and activation of neutrophilsImmunologic relationship between platelet membrane glycoprotein GPIIb/IIIa and cell surface molecules expressed by a variety of cells.Platelet glycoproteins IIb and IIIa: evidence for a family of immunologically and structurally related glycoproteins in mammalian cells.The molecular genetic basis of Glanzmann thrombasthenia in the Iraqi-Jewish and Arab populations in IsraelThe platelet fibrinogen receptor: from megakaryocyte to the mortuary.Blood elements at surfaces: platelets.alphaIIbbeta3 biogenesis is controlled by engagement of alphaIIb in the calnexin cycle via the N15-linked glycan.Mutations in and near the second calcium-binding domain of integrin alphaIIb affect the structure and function of integrin alphaIIbbeta3.The inhibitory effect of apolipoprotein E4 on neurite outgrowth is associated with microtubule depolymerization.Biosynthesis and processing of platelet GPIIb-IIIa in human megakaryocytes.The platelet fibrinogen receptor: an immunogold-surface replica study of agonist-induced ligand binding and receptor clustering.Comparative study of the glycosylation of platelet glycoprotein GPIIb/IIIa and the vitronectin receptor. Differential processing of their beta-subunitInterchain and intrachain disulphide bonds in human platelet glycoprotein IIb. Localization of the epitopes for several monoclonal antibodies.Detection of integrin alpha IIbbeta 3 clustering in living cells.Two genetic defects in alphaIIb are associated with type I Glanzmann's thrombasthenia in a Great Pyrenees dog: a 14-base insertion in exon 13 and a splicing defect of intron 13.The extreme C-terminal region of kindlin-2 is critical to its regulation of integrin activation.No genetic abnormalities identified in α2IIb and β3: phenotype overcomes genotype in Glanzmann thrombasthenia.Novel mutations of integrin αIIb and β3 genes in Turkish children with Glanzmann's thrombasthenia.A new multiplex PCR and conformation-sensitive gel electrophoresis strategy for mutation detection in the platelet glycoprotein alphaIIb and beta3 genes.
P2860
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P2860
Biogenesis of the platelet receptor for fibrinogen: evidence for separate precursors for glycoproteins IIb and IIIa.
description
1986 nî lūn-bûn
@nan
1986年の論文
@ja
1986年論文
@yue
1986年論文
@zh-hant
1986年論文
@zh-hk
1986年論文
@zh-mo
1986年論文
@zh-tw
1986年论文
@wuu
1986年论文
@zh
1986年论文
@zh-cn
name
Biogenesis of the platelet rec ...... or glycoproteins IIb and IIIa.
@ast
Biogenesis of the platelet rec ...... or glycoproteins IIb and IIIa.
@en
type
label
Biogenesis of the platelet rec ...... or glycoproteins IIb and IIIa.
@ast
Biogenesis of the platelet rec ...... or glycoproteins IIb and IIIa.
@en
prefLabel
Biogenesis of the platelet rec ...... or glycoproteins IIb and IIIa.
@ast
Biogenesis of the platelet rec ...... or glycoproteins IIb and IIIa.
@en
P2093
P2860
P356
P1476
Biogenesis of the platelet rec ...... or glycoproteins IIb and IIIa.
@en
P2093
P2860
P304
P356
10.1073/PNAS.83.5.1480
P407
P577
1986-03-01T00:00:00Z