Pharmacokinetic and pharmacodynamic considerations in gene therapy.
about
Particle tracking analysis for the intracellular trafficking of nanoparticles modified with African swine fever virus protein p54-derived peptideQuantitative analysis of condensation/decondensation status of pDNA in the nuclear sub-domains by QD-FRET.Imaging transgene activity in vivo.Multi-level kinetic model of mRNA delivery via transfection of lipoplexes.Octaarginine-modified multifunctional envelope-type nanoparticles for gene deliveryQuantitative and mechanism-based investigation of post-nuclear delivery events between adenovirus and lipoplex.A pH-sensitive multifunctional gene carrier assembled via layer-by-layer technique for efficient gene delivery.Light-directed gene delivery by photochemical internalisation.Transferrin-PEG-PE modified dexamethasone conjugated cationic lipid carrier mediated gene delivery system for tumor-targeted transfection.Delivery of macromolecules using arginine-rich cell-penetrating peptides: ways to overcome endosomal entrapment.Delivery to mitochondria: a narrower approach for broader therapeutics.Preclinical development of therapeutic biologics.Nanostructured lipid carriers as novel drug delivery system for lung cancer gene therapy.A neutral envelope-type nanoparticle containing pH-responsive and SS-cleavable lipid-like material as a carrier for plasmid DNA.Phospholipid-Nucleic Acid Complexation: Biomolecular Energetics of DNA-Mg(2+)-Phosphatidylcholine Ternary Complex Formation, Compaction and Relevance as Lipoplex Formulation.Development of a novel systemic gene delivery system for cancer therapy with a tumor-specific cleavable PEG-lipid.Sunflower-shaped cyclodextrin-conjugated poly(epsilon-lysine) polyplex as a controlled intracellular trafficking device.A model for intracellular trafficking of adenoviral vectors.Three-Layered Biodegradable Micelles Prepared by Two-Step Self-Assembly of PLA-PEI-PLA and PLA-PEG-PLA Triblock Copolymers as Efficient Gene Delivery System.Correlation between transgen expression and plasmid DNA loss in mouse liver.Transient expression of Drosophila melanogaster deoxynucleoside kinase gene enhances cytotoxicity of nucleoside analogs.A designed curved DNA sequence remarkably enhances transgene expression from plasmid DNA in mouse liver.Dual ligands modified double targeted nano-system for liver targeted gene delivery.
P2860
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P2860
Pharmacokinetic and pharmacodynamic considerations in gene therapy.
description
2003 nî lūn-bûn
@nan
2003年の論文
@ja
2003年論文
@yue
2003年論文
@zh-hant
2003年論文
@zh-hk
2003年論文
@zh-mo
2003年論文
@zh-tw
2003年论文
@wuu
2003年论文
@zh
2003年论文
@zh-cn
name
Pharmacokinetic and pharmacodynamic considerations in gene therapy.
@ast
Pharmacokinetic and pharmacodynamic considerations in gene therapy.
@en
type
label
Pharmacokinetic and pharmacodynamic considerations in gene therapy.
@ast
Pharmacokinetic and pharmacodynamic considerations in gene therapy.
@en
prefLabel
Pharmacokinetic and pharmacodynamic considerations in gene therapy.
@ast
Pharmacokinetic and pharmacodynamic considerations in gene therapy.
@en
P2093
P1433
P1476
Pharmacokinetic and pharmacodynamic considerations in gene therapy.
@en
P2093
Hidetaka Akita
Hideyoshi Harashima
Hiroyuki Kamiya
P304
P356
10.1016/S1359-6446(03)02889-7
P577
2003-11-01T00:00:00Z