Studying clonal dynamics in response to cancer therapy using high-complexity barcoding.
about
The steady progress of targeted therapies, promising advances for lung cancerCancer Evolution and the Limits of Predictability in Precision Cancer MedicineThe influence of subclonal resistance mutations on targeted cancer therapyA high-content image-based method for quantitatively studying context-dependent cell population dynamicsMolecular Characterization of Epithelial Ovarian Cancer: Implications for Diagnosis and TreatmentMolecular pathology of cancer: how to communicate with diseasePatient-derived tumour xenografts for breast cancer drug discoveryModel Based Analysis of Clonal Developments Allows for Early Detection of Monoclonal Conversion and LeukemiaModeling Tumor Clonal Evolution for Drug Combinations DesignGlucose metabolism-targeted therapy and withaferin A are effective for epidermal growth factor receptor tyrosine kinase inhibitor-induced drug-tolerant persisters.Clonal competition in BcrAbl-driven leukemia: how transplantations can accelerate clonal conversion.TKI-addicted ROS1-rearranged cells are destined to survival or death by the intensity of ROS1 kinase activity.Big-data-based edge biomarkers: study on dynamical drug sensitivity and resistance in individuals.The Human Glioblastoma Cell Culture Resource: Validated Cell Models Representing All Molecular Subtypes.Site-specific recombinatorics: in situ cellular barcoding with the Cre Lox systemAn in vivo multiplexed small-molecule screening platform.Limitations and challenges of genetic barcode quantification.SIApopr: A computational method to simulate evolutionary branching trees for analysis of tumor clonal evolution.Improving Cancer Treatment via Mathematical Modeling: Surmounting the Challenges Is Worth the EffortImplementation of In Vitro Drug Resistance Assays: Maximizing the Potential for Uncovering Clinically Relevant Resistance Mechanisms.Developmental Insights into Breast Cancer Intratumoral Heterogeneity.Diverse drug-resistance mechanisms can emerge from drug-tolerant cancer persister cells.When (distant) relatives stay too long: implications for cancer medicine.Tumor cells can follow distinct evolutionary paths to become resistant to epidermal growth factor receptor inhibition.A Perspective on Implementing a Quantitative Systems Pharmacology Platform for Drug Discovery and the Advancement of Personalized Medicine.De novo intrachromosomal gene conversion from OPN1MW to OPN1LW in the male germline results in Blue Cone MonochromacyReciprocal positive selection for weakness - preventing olaparib resistance by inhibiting BRCA2.Differential selective pressure alters rate of drug resistance acquisition in heterogeneous tumor populations.Exploiting Temporal Collateral Sensitivity in Tumor Clonal Evolution.Cancer cells exhibit clonal diversity in phenotypic plasticity.The impact of structural biology in medicine illustrated with four case studies.JNK Pathway Activation Modulates Acquired Resistance to EGFR/HER2-Targeted Therapies.Intra-tumour heterogeneity - going beyond genetics.Profiling lung adenocarcinoma by liquid biopsy: can one size fit all?Targeting metastasis.Genetic analysis of uterine aspirates improves the diagnostic value and captures the intra-tumor heterogeneity of endometrial cancers.Intratumoral heterogeneity: pathways to treatment resistance and relapse in human glioblastoma.Proteogenomic studies on cancer drug resistance: towards biomarker discovery and target identification.Clonal cooperativity in heterogenous cancers.Hypermutation signature reveals a slippage and realignment model of translesion synthesis by Rev3 polymerase in cisplatin-treated yeast.
P2860
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P2860
Studying clonal dynamics in response to cancer therapy using high-complexity barcoding.
description
2015 nî lūn-bûn
@nan
2015年の論文
@ja
2015年論文
@yue
2015年論文
@zh-hant
2015年論文
@zh-hk
2015年論文
@zh-mo
2015年論文
@zh-tw
2015年论文
@wuu
2015年论文
@zh
2015年论文
@zh-cn
name
Studying clonal dynamics in response to cancer therapy using high-complexity barcoding.
@ast
Studying clonal dynamics in response to cancer therapy using high-complexity barcoding.
@en
type
label
Studying clonal dynamics in response to cancer therapy using high-complexity barcoding.
@ast
Studying clonal dynamics in response to cancer therapy using high-complexity barcoding.
@en
prefLabel
Studying clonal dynamics in response to cancer therapy using high-complexity barcoding.
@ast
Studying clonal dynamics in response to cancer therapy using high-complexity barcoding.
@en
P2093
P2860
P50
P356
P1433
P1476
Studying clonal dynamics in response to cancer therapy using high-complexity barcoding
@en
P2093
Alina Raza
Angad P Singh
Daniel Rakiec
David A Ruddy
Frank Stegmeier
Franziska Michor
Joshua M Korn
Justina X Caushi
Marissa Balak
P2860
P2888
P304
P356
10.1038/NM.3841
P407
P577
2015-04-13T00:00:00Z