about
Uncoupling of RNAi from active translation in mammalian cells.Methodological obstacles in knocking down small noncoding RNAsInhibition of HIV-1 gene expression by retroviral vector-mediated small-guide RNAs that direct specific RNA cleavage by tRNase ZLModulating HIV-1 replication by RNA interference directed against human transcription elongation factor SPT5Insights into the kinetics of siRNA-mediated gene silencing from live-cell and live-animal bioluminescent imagingImprovements in siRNA properties mediated by 2'-deoxy-2'-fluoro-beta-D-arabinonucleic acid (FANA)Engineered external guide sequences are highly effective in inducing RNase P for inhibition of gene expression and replication of human cytomegalovirusAOBase: a database for antisense oligonucleotides selection and design.RNA tectonics (tectoRNA) for RNA nanostructure design and its application in synthetic biologyAutomated design of hammerhead ribozymes and validation by targeting the PABPN1 gene transcript.Survivin as a target for new anticancer interventionsErbin inhibits RAF activation by disrupting the sur-8-Ras-Raf complexInhibition of dengue virus entry and multiplication into monocytes using RNA interferenceDose optimization for long-term rAAV-mediated RNA interference in the nigrostriatal projection neuronsRNase P Ribozymes Inhibit the Replication of Human Cytomegalovirus by Targeting Essential Viral Capsid ProteinsNonviral gene transfer to skeletal, smooth, and cardiac muscle in living animalsTrafficking through the Rev/RRE pathway is essential for efficient inhibition of human immunodeficiency virus type 1 by an antisense RNA derived from the envelope gene.Generation of an external guide sequence library for a reverse genetic screen in Caenorhabditis elegans.Characterization of interaction between cationic lipid-oligonucleotide complexes and cellular membrane lipids using confocal imaging and fluorescence correlation spectroscopyStructural rearrangements in RNA on the binding of an antisense oligonucleotide: implications for the study of intra-molecular RNA interactions and the design of cooperatively acting antisense reagents with enhanced efficacy.Gene discovery by ribozyme and siRNA libraries.Selection of antisense oligonucleotides based on multiple predicted target mRNA structures.Gene silencing by cell-penetrating, sequence-selective and nucleic-acid hydrolyzing antibodiesIncreased interstitial pressure improves nucleic acid delivery to skin enabling a comparative analysis of constitutive promoters.Dissecting human cytomegalovirus gene function and capsid maturation by ribozyme targeting and electron cryomicroscopyEngineered RNase P ribozymes effectively inhibit human cytomegalovirus gene expression and replicationActivation and deactivation of DNAzyme and antisense function with light for the photochemical regulation of gene expression in mammalian cellsSalmonella-mediated delivery of RNase P-based ribozymes for inhibition of viral gene expression and replication in human cells.Genetic control of de novo lipogenesis: role in diet-induced obesityNorthern blotting analysis of microRNAs, their precursors and RNA interference triggers.Regulation of oxidative stress response by CosR, an essential response regulator in Campylobacter jejuni.Use of bicistronic vectors in combination with flow cytometry to screen for effective small interfering RNA target sequencesTherapeutic RNA manipulation in liver disease.Engineered external guide sequences effectively block viral gene expression and replication in cultured cells.Effective inhibition of human immunodeficiency virus 1 replication by engineered RNase P ribozyme.Application of phi29 motor pRNA for targeted therapeutic delivery of siRNA silencing metallothionein-IIA and survivin in ovarian cancersOral delivery of RNase P ribozymes by Salmonella inhibits viral infection in mice.Functional interrogation of breast cancer: from models to drugs.RNA interference for improving the outcome of islet transplantation.Engineered external guide sequences are highly effective in inhibiting gene expression and replication of hepatitis B virus in cultured cells.
P2860
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P2860
description
2003 nî lūn-bûn
@nan
2003年の論文
@ja
2003年論文
@yue
2003年論文
@zh-hant
2003年論文
@zh-hk
2003年論文
@zh-mo
2003年論文
@zh-tw
2003年论文
@wuu
2003年论文
@zh
2003年论文
@zh-cn
name
Approaches for the sequence-specific knockdown of mRNA.
@ast
Approaches for the sequence-specific knockdown of mRNA.
@en
type
label
Approaches for the sequence-specific knockdown of mRNA.
@ast
Approaches for the sequence-specific knockdown of mRNA.
@en
prefLabel
Approaches for the sequence-specific knockdown of mRNA.
@ast
Approaches for the sequence-specific knockdown of mRNA.
@en
P356
P1433
P1476
Approaches for the sequence-specific knockdown of mRNA.
@en
P2093
John J Rossi
Lisa J Scherer
P2888
P304
P356
10.1038/NBT915
P577
2003-12-01T00:00:00Z
P5875
P6179
1003713111