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Pathological and protective roles of glia in chronic painThe "toll" of opioid-induced glial activation: improving the clinical efficacy of opioids by targeting gliaNeuropathic pain activates the endogenous kappa opioid system in mouse spinal cord and induces opioid receptor toleranceKinin B1 receptors: key G-protein-coupled receptors and their role in inflammatory and painful processesChemokines and the pathophysiology of neuropathic painControlling neuropathic pain by adeno-associated virus driven production of the anti-inflammatory cytokine, interleukin-10Intrathecal long-term gene expression by self-complementary adeno-associated virus type 1 suitable for chronic pain studies in ratsPain and Poppies: The Good, the Bad, and the Ugly of Opioid AnalgesicsMechanisms of acupuncture-electroacupuncture on persistent painBrain-derived neurotrophic factor from microglia: a molecular substrate for neuropathic painSpinal Plasticity and Behavior: BDNF-Induced Neuromodulation in Uninjured and Injured Spinal CordEmerging targets in neuroinflammation-driven chronic painTLR 2 and 4 responsiveness from isolated peripheral blood mononuclear cells from rats and humans as potential chronic pain biomarkersInvolvement of subtype 1 metabotropic glutamate receptors in apoptosis and caspase-7 over-expression in spinal cord of neuropathic ratsInhibition of spinal microglial cathepsin S for the reversal of neuropathic painRapid co-release of interleukin 1beta and caspase 1 in spinal cord inflammationGlutamate-mediated astrocyte-to-neuron signalling in the rat dorsal horn.Enduring reversal of neuropathic pain by a single intrathecal injection of adenosine 2A receptor agonists: a novel therapy for neuropathic pain.Astroglia in medullary dorsal horn (trigeminal spinal subnucleus caudalis) are involved in trigeminal neuropathic pain mechanisms.Polyamidoamine dendrimer-conjugated triamcinolone acetonide attenuates nerve injury-induced spinal cord microglia activation and mechanical allodynia.Etanercept attenuates thermal and mechanical hyperalgesia induced by bone cancer.A Decade of Research on TLR2 Discovering Its Pivotal Role in Glial Activation and Neuroinflammation in Neurodegenerative Diseases.Puerarin alleviates neuropathic pain by inhibiting neuroinflammation in spinal cord.Generation of an immortalized astrocyte cell line from H-2Kb-tsA58 mice to study the role of astrocytes in brain metastasis.Flexibilide obtained from cultured soft coral has anti-neuroinflammatory and analgesic effects through the upregulation of spinal transforming growth factor-β1 in neuropathic ratsDelta-opioid receptor analgesia is independent of microglial activation in a rat model of neuropathic painNeuropathic pain model of peripheral neuropathies mediated by mutations of glycyl-tRNA synthetaseKey role for spinal dorsal horn microglial kinin B1 receptor in early diabetic pain neuropathy.Expression profiling of genes modulated by minocycline in a rat model of neuropathic painA p38 mitogen-activated protein kinase-dependent mechanism of disinhibition in spinal synaptic transmission induced by tumor necrosis factor-alpha.The use of ketamine in complex regional pain syndrome: possible mechanisms.Role of vitamin D3 in treatment of lumbar disc herniation--pain and sensory aspects: study protocol for a randomized controlled trial.Medication-overuse headache and opioid-induced hyperalgesia: A review of mechanisms, a neuroimmune hypothesis and a novel approach to treatment.Carbon monoxide reduces neuropathic pain and spinal microglial activation by inhibiting nitric oxide synthesis in miceIncreased responsiveness of peripheral blood mononuclear cells to in vitro TLR 2, 4 and 7 ligand stimulation in chronic pain patientsRole of the immune system in chronic pain.Temporomandibular joint inflammation activates glial and immune cells in both the trigeminal ganglia and in the spinal trigeminal nucleusBotulinum toxin therapy for osteoarticular pain: an evidence-based reviewTRAF6 upregulation in spinal astrocytes maintains neuropathic pain by integrating TNF-α and IL-1β signalingIbudilast (AV-411). A new class therapeutic candidate for neuropathic pain and opioid withdrawal syndromes.
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P2860
description
2003 nî lūn-bûn
@nan
2003年の論文
@ja
2003年論文
@yue
2003年論文
@zh-hant
2003年論文
@zh-hk
2003年論文
@zh-mo
2003年論文
@zh-tw
2003年论文
@wuu
2003年论文
@zh
2003年论文
@zh-cn
name
Glia: a novel drug discovery target for clinical pain.
@ast
Glia: a novel drug discovery target for clinical pain.
@en
type
label
Glia: a novel drug discovery target for clinical pain.
@ast
Glia: a novel drug discovery target for clinical pain.
@en
prefLabel
Glia: a novel drug discovery target for clinical pain.
@ast
Glia: a novel drug discovery target for clinical pain.
@en
P356
P1476
Glia: a novel drug discovery target for clinical pain.
@en
P2093
Linda R Watkins
Steven F Maier
P2888
P304
P356
10.1038/NRD1251
P577
2003-12-01T00:00:00Z