Opportunities in somatostatin research: biological, chemical and therapeutic aspects. - Wikidata - awgldk - TriplyDB

Opportunities in somatostatin research: biological, chemical and therapeutic aspects.

Opportunities in somatostatin research: biological, chemical and therapeutic aspects.

http://www.wikidata.org/entity/Q35600019

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Direct binding of p85 to sst2 somatostatin receptor reveals a novel mechanism for inhibiting PI3K pathway Coexpression of human somatostatin receptor-2 (SSTR2) and SSTR3 modulates antiproliferative signaling and apoptosis Pituitary somatostatin receptor signaling Acromegaly pathogenesis and treatment Medical treatment for gastro-entero-pancreatic neuroendocrine tumours PI3K-AKT-mTOR-signaling and beyond: the complex network in gastroenteropancreatic neuroendocrine neoplasms Fine-tuning somatostatin receptor signalling by agonist-selective phosphorylation and dephosphorylation: IUPHAR Review 5 Laminar and cellular analyses of reduced somatostatin gene expression in the subgenual anterior cingulate cortex in major depression Improving binding affinity and stability of peptide ligands by substituting glycines with D-amino acids Summary of emerging personalized medicine in neuroendocrine tumors: are we on track?Bardet-Biedl syndrome proteins are required for the localization of G protein-coupled receptors to primary cilia Role of somatostatin receptor-2 in gentamicin-induced auditory hair cell loss in the Mammalian inner ear A potential role of somatostatin and its receptor SSTR4 in the migration of hepatic oval cells Somatostatin inhibits cell migration and reduces cell counts of human keratinocytes and delays epidermal wound healing in an ex vivo wound model Somatostatin receptor expression on von Hippel-Lindau-associated hemangioblastomas offers novel therapeutic target.Expression of somatostatin and somatostatin receptor subtypes 1-5 in human normal and diseased kidney.Conformationally homogeneous heterocyclic pseudotetrapeptides as three-dimensional scaffolds for rational drug design: receptor-selective somatostatin analogues.Peptide-based probes for targeted molecular imaging.Regulation of somatostatin receptor 4-mediated cytostatic effects by CD26 in malignant pleural mesothelioma Does somatostatin have a role in the regulation of cortisol secretion in primary pigmented nodular adrenocortical disease (ppnad)? a clinical and in vitro investigation.Acromegaly clinical trial methodology impact on reported biochemical efficacy rates of somatostatin receptor ligand treatments: a meta-analysis.Pasireotide and octreotide stimulate distinct patterns of sst2A somatostatin receptor phosphorylation.Peptides and peptide hormones for molecular imaging and disease diagnosis Synthesis of chemically modified bioactive peptides: recent advances, challenges and developments for medicinal chemistry.The combination of prolinoamino acids and cyclopropylamino acids leads to fully functionalized, stable β-turns in water.Recent trends and observations in the design of high-quality screening collections.A novel suspension formulation enhances intestinal absorption of macromolecules via transient and reversible transport mechanisms.Somatostatin and cancer: applying endocrinology to oncology.The lipophilic bullet hits the targets: medicinal chemistry of adamantane derivatives Suvorexant for the treatment of insomnia.Contrasting Effects of the Neuropeptides Substance P, Somatostatin, and Neuropeptide Y on the Methamphetamine-Induced Production of Striatal Nitric Oxide in Mice.Radiolabelled GLP-1 analogues for in vivo targeting of insulinomas.Pharmacological management of Cushing's syndrome: an update.Differential temporal and spatial regulation of somatostatin receptor phosphorylation and dephosphorylation.Effects of octreotide and insulin on colon cancer cellular proliferation and correlation with hTERT activity Foxa1 and Foxa2 control the differentiation of goblet and enteroendocrine L- and D-cells in mice Somatostatin Receptors in Lung Cancer: From Function to Molecular Imaging and Therapeutics Radiolabeled somatostatin receptor antagonists are preferable to agonists for in vivo peptide receptor targeting of tumors.Could Somatostatin Enhance the Outcomes of Chemotherapeutic Treatment in SCLC?Somatostatin receptor biology in neuroendocrine and pituitary tumours: part 1--molecular pathways.

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P2860

Opportunities in somatostatin research: biological, chemical and therapeutic aspects.

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