Definition of a discontinuous immunodominant epitope at the NH2 terminus of the La/SS-B ribonucleoprotein autoantigen.
about
One gene, two transcripts: isolation of an alternative transcript encoding for the autoantigen La/SS-B from a cDNA library of a patient with primary Sjögrens' syndromeAutoantibodies against the replication protein A complex in systemic lupus erythematosus and other autoimmune diseases.Fine specificity of the autoimmune response to the Ro/SSA and La/SSB ribonucleoproteins.Identification of a human-specific epitope in a conserved region of the La/SS-B autoantigen.Hierarchical self-tolerance to T cell determinants within the ubiquitous nuclear self-antigen La (SS-B) permits induction of systemic autoimmunity in normal mice.How does autoimmunity to La and Ro initiate and spread?An immunodominant La/SSB autoantibody proteome derives from public clonotypes.Anti-La/SSB antibodies transported across the placenta bind apoptotic cells in fetal organs targeted in neonatal lupus.Restricted Specificity of Intermolecular Spreading to Endogenous La (SS-B) and 60 kDa Ro (SS-A) in Experimental AutoimmunityMolecular chaperones are targets of autoimmunity in Ro(SS-A) immune mice
P2860
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P2860
Definition of a discontinuous immunodominant epitope at the NH2 terminus of the La/SS-B ribonucleoprotein autoantigen.
description
1992 nî lūn-bûn
@nan
1992年の論文
@ja
1992年論文
@yue
1992年論文
@zh-hant
1992年論文
@zh-hk
1992年論文
@zh-mo
1992年論文
@zh-tw
1992年论文
@wuu
1992年论文
@zh
1992年论文
@zh-cn
name
Definition of a discontinuous ...... ribonucleoprotein autoantigen.
@ast
Definition of a discontinuous ...... ribonucleoprotein autoantigen.
@en
type
label
Definition of a discontinuous ...... ribonucleoprotein autoantigen.
@ast
Definition of a discontinuous ...... ribonucleoprotein autoantigen.
@en
prefLabel
Definition of a discontinuous ...... ribonucleoprotein autoantigen.
@ast
Definition of a discontinuous ...... ribonucleoprotein autoantigen.
@en
P2093
P2860
P356
P1476
Definition of a discontinuous ...... ribonucleoprotein autoantigen.
@en
P2093
Guidolin A
Macmillan E
McNeilage LJ
Umapathysivam K
Whittingham S
P2860
P304
P356
10.1172/JCI115762
P407
P577
1992-05-01T00:00:00Z