Frequent MED12 mutations in phyllodes tumours of the breast.
about
Expression of CDK8 and CDK8-interacting Genes as Potential Biomarkers in Breast CancerMediator kinase module and human tumorigenesisPhyllodes tumours of the breast: a consensus reviewMassively parallel sequencing analysis of synchronous fibroepithelial lesions supports the concept of progression from fibroadenoma to phyllodes tumor.Mutational analysis of MED12 in fibroadenomas and phyllodes tumors of the breast by means of targeted next-generation sequencing.Uterine adenosarcomas are mesenchymal neoplasms.TERT promoter mutations are frequent and show association with MED12 mutations in phyllodes tumors of the breast.Characterization of a murine xenograft model for contrast agent development in breast lesion malignancy assessment.Germline BRCA2 mutations drive prostate cancers with distinct evolutionary trajectories.Tubular, lactating, and ductal adenomas are devoid of MED12 Exon2 mutations, and ductal adenomas show recurrent mutations in GNAS and the PI3K-AKT pathway.Phyllodes Tumor in a Lactating Breast.Genetic analysis of uterine adenosarcomas and phyllodes tumors of the breast.MED12 is frequently mutated in breast phyllodes tumours: a study of 112 cases.Phyllodes tumors with and without fibroadenoma-like areas display distinct genomic features and may evolve through distinct pathways.Genomic profiling of malignant phyllodes tumors reveals aberrations in FGFR1 and PI-3 kinase/RAS signaling pathways and provides insights into intratumoral heterogeneity.Clinicopathology and treatment of a giant malignant phyllodes tumor of the breast: A case report and literature review.Size and heterologous elements predict metastases in malignant phyllodes tumours of the breast.Comprehensive screening for MED12 mutations in gynaecological mesenchymal tumours identified morphologically distinctive mixed epithelial and stromal tumours.Med12 regulates ovarian steroidogenesis, uterine development and maternal effects in the mammalian egg.MED12, TERT promoter and RBM15 mutations in primary and recurrent phyllodes tumours.The mediator complex in genomic and non-genomic signaling in cancer.MED12 protein expression in breast fibroepithelial lesions: correlation with mutation status and oestrogen receptor expression.Comprehensive genomic profiling of malignant phyllodes tumors of the breast.MED12 exon 2 mutation as a highly sensitive and specific marker in distinguishing phyllodes tumours from other spindle neoplasms of the breast.Frequency of MED12 mutations in phyllodes tumors: Inverse correlation with histologic grade.
P2860
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P2860
Frequent MED12 mutations in phyllodes tumours of the breast.
description
2015 nî lūn-bûn
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2015年の論文
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2015年論文
@yue
2015年論文
@zh-hant
2015年論文
@zh-hk
2015年論文
@zh-mo
2015年論文
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2015年论文
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2015年论文
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2015年论文
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name
Frequent MED12 mutations in phyllodes tumours of the breast.
@ast
Frequent MED12 mutations in phyllodes tumours of the breast.
@en
type
label
Frequent MED12 mutations in phyllodes tumours of the breast.
@ast
Frequent MED12 mutations in phyllodes tumours of the breast.
@en
prefLabel
Frequent MED12 mutations in phyllodes tumours of the breast.
@ast
Frequent MED12 mutations in phyllodes tumours of the breast.
@en
P2093
P2860
P356
P1476
Frequent MED12 mutations in phyllodes tumours of the breast.
@en
P2093
A Maeshima
T Kinoshita
P2860
P2888
P304
P356
10.1038/BJC.2015.116
P407
P577
2015-04-02T00:00:00Z
P6179
1025502654