Targeting cMET with INC280 impairs tumour growth and improves efficacy of gemcitabine in a pancreatic cancer model - Wikidata - awgldk - TriplyDB

Targeting cMET with INC280 impairs tumour growth and improves efficacy of gemcitabine in a pancreatic cancer model

Targeting cMET with INC280 impairs tumour growth and improves efficacy of gemcitabine in a pancreatic cancer model

http://www.wikidata.org/entity/Q35605388

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Hepatocyte Growth Factor from a Clinical Perspective: A Pancreatic Cancer Challenge Ockham's razor for the MET-driven invasive growth linking idiopathic pulmonary fibrosis and cancer Histone deacetylases, microRNA and leptin crosstalk in pancreatic cancer.Characterization of novel carcinoma cell lines for the analysis of therapeutical strategies fighting pancreatic cancer Kaempferol Inhibits Pancreatic Cancer Cell Growth and Migration through the Blockade of EGFR-Related Pathway In Vitro.Hepatocyte growth factor inhibition: a novel therapeutic approach in pancreatic cancer C-Met as a potential target for the treatment of gastrointestinal cancer: Current status and future perspectives.Preclinical Evaluation of MET Inhibitor INC-280 With or Without the Epidermal Growth Factor Receptor Inhibitor Erlotinib in Non-Small-Cell Lung Cancer.Prognostic value of c-Met overexpression in pancreatic adenocarcinoma: a meta-analysis.Prognostic value of c-Met overexpression in hepatocellular carcinoma: a meta-analysis and review.Targeting the HGF/c-MET pathway: stromal remodelling in pancreatic cancer.Targeted therapy of gastroenteropancreatic neuroendocrine tumours: preclinical strategies and future targets.The evolution into personalized therapies in pancreatic ductal adenocarcinoma: challenges and opportunities.Inhibition of mTORC2/RICTOR Impairs Melanoma Hepatic Metastasis

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Targeting cMET with INC280 impairs tumour growth and improves efficacy of gemcitabine in a pancreatic cancer model

http://www.wikidata.org/entity/Q35605388

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Targeting cMET with INC280 imp ...... e in a pancreatic cancer model

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Christine Wagner

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Edward Kenneth Geissler

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Franziska Brandes

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Hans Jürgen Schlitt

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Julia Redekopf

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Katharina Schmidt

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Sven Arke Lang

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P2860

Targeting the hepatocyte growth factor-cMET axis in cancer therapy

Met receptor tyrosine kinase signaling induces secretion of the angiogenic chemokine interleukin-8/CXCL8 in pancreatic cancer

Cancer statistics, 2013

A selective small molecule inhibitor of c-Met kinase inhibits c-Met-dependent phenotypes in vitro and exhibits cytoreductive antitumor activity in vivo

MetMAb, the one-armed 5D5 anti-c-Met antibody, inhibits orthotopic pancreatic tumor growth and improves survival

Essential role for the c-met receptor in the migration of myogenic precursor cells into the limb bud

FOLFIRINOX versus gemcitabine for metastatic pancreatic cancer

Inhibiting the interaction of cMET and IGF-1R with FAK effectively reduces growth of pancreatic cancer cells in vitro and in vivo

HIF-1 activation induces doxorubicin resistance in MCF7 3-D spheroids via P-glycoprotein expression: a potential model of the chemo-resistance of invasive micropapillary carcinoma of the breast.

Crizotinib inhibits metabolic inactivation of gemcitabine in c-Met-driven pancreatic carcinoma.

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