Epiligrin, the major human keratinocyte integrin ligand, is a target in both an acquired autoimmune and an inherited subepidermal blistering skin disease
about
A cell signal pathway involving laminin-5, alpha3beta1 integrin, and mitogen-activated protein kinase can regulate epithelial cell proliferationAnchorage mediated by integrin alpha6beta4 to laminin 5 (epiligrin) regulates tyrosine phosphorylation of a membrane-associated 80-kD proteinMolecular diagnosis in autoimmune skin blistering conditionsMucous membrane pemphigoidDemonstration of the molecular shape of BP180, a 180-kDa bullous pemphigoid antigen and its potential for trimer formationFibulin-2 binds to the short arms of laminin-5 and laminin-1 via conserved amino acid sequencesAnti-laminin gamma-1 pemphigoidThe LG3 module of laminin-5 harbors a binding site for integrin alpha3beta1 that promotes cell adhesion, spreading, and migration.Laryngo-onycho-cutaneous syndrome: an inherited epithelial defectParaneoplastic cicatricial pemphigoid.Defining the role of laminin-332 in carcinoma.Non-plaque-induced gingival lesions.Laminins and human disease.Distinct and overlapping ligand specificities of the alpha 3A beta 1 and alpha 6A beta 1 integrins: recognition of laminin isoforms.Differential expression of laminin 5 (alpha 3 beta 3 gamma 2) by human malignant and normal prostate.Expression of hemidesmosomal and extracellular matrix proteins by normal and malignant human prostate tissueHemidesmosomes and focal contact proteins: functions and cross-talk in keratinocytes, bullous diseases and wound healing.alpha3beta1 Integrin is required for normal development of the epidermal basement membrane.Extent of laminin-5 assembly and secretion effect junctional epidermolysis bullosa phenotype.IgG anti-laminin-332 autoantibodies are present in a subset of patients with mucous membrane, but not bullous, pemphigoid.Passive transfer of anti-laminin 5 antibodies induces subepidermal blisters in neonatal mice.Pemphigoid diseases: pathogenesis, diagnosis, and treatment.Urban legend series: mucous membrane pemphigoid.Blistering disease: insight from the hemidesmosome and other components of the dermal-epidermal junction.Sensitivity of different assays for the serological diagnosis of epidermolysis bullosa acquisita: analysis of a cohort of 24 Italian patients.Studies of patients with anti-epiligrin cicatricial pemphigoid.Epidermolysis bullosa acquisita localized to the face.The role of laminins in basement membrane function.Epiligrin, a component of epithelial basement membranes, is an adhesive ligand for alpha 3 beta 1 positive T lymphocytesMurine laminin alpha3A and alpha3B isoform chains are generated by usage of two promoters and alternative splicing.Kalinin is more efficient than laminin in promoting adhesion of primary keratinocytes and some other epithelial cells and has a different requirement for integrin receptors.A case of antiepiligrin cicatricial pemphigoid with nephrotic syndrome.Mucous membrane pemphigoid: a dual circulating antibody response with IgG and IgA signifies a more severe and persistent disease.Acquired junctional epidermolysis bullosa associated with IgG autoantibodies to the beta subunit of laminin-5.Immunofluorescence serration pattern analysis as a diagnostic criterion in antilaminin-332 mucous membrane pemphigoid: immunopathological findings and clinical experience in 10 Dutch patients.Anti-laminin-332 mucous membrane pemphigoid in a 9-year old girl.Molecular diagnosis of anti-laminin 332 (epiligrin) mucous membrane pemphigoid.Diagnosis of Autoimmune Blistering Diseases
P2860
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P2860
Epiligrin, the major human keratinocyte integrin ligand, is a target in both an acquired autoimmune and an inherited subepidermal blistering skin disease
description
1992 nî lūn-bûn
@nan
1992年の論文
@ja
1992年論文
@yue
1992年論文
@zh-hant
1992年論文
@zh-hk
1992年論文
@zh-mo
1992年論文
@zh-tw
1992年论文
@wuu
1992年论文
@zh
1992年论文
@zh-cn
name
Epiligrin, the major human ker ...... dermal blistering skin disease
@ast
Epiligrin, the major human ker ...... dermal blistering skin disease
@en
type
label
Epiligrin, the major human ker ...... dermal blistering skin disease
@ast
Epiligrin, the major human ker ...... dermal blistering skin disease
@en
prefLabel
Epiligrin, the major human ker ...... dermal blistering skin disease
@ast
Epiligrin, the major human ker ...... dermal blistering skin disease
@en
P2093
P2860
P356
P1476
Epiligrin, the major human ker ...... dermal blistering skin disease
@en
P2093
K B Yancey
N Domloge-Hultsch
R A Briggaman
W G Carter
W R Gammon
P2860
P304
P356
10.1172/JCI116033
P407
P577
1992-10-01T00:00:00Z