New insights on the mechanism(s) of the dominant negative effect of mutant thyroid hormone receptor in generalized resistance to thyroid hormone.
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Homozygous thyroid hormone receptor β-gene mutations in resistance to thyroid hormone: three new cases and review of the literature.Transcription factors in inner ear developmentInteraction of human beta 1 thyroid hormone receptor and its mutants with DNA and retinoid X receptor beta. T3 response element-dependent dominant negative potencyAutoimmunity in patients with resistance to thyroid hormone.Genetic analysis of 29 kindreds with generalized and pituitary resistance to thyroid hormone. Identification of thirteen novel mutations in the thyroid hormone receptor beta gene[Thyroid hormone resistance syndrome].Alpha and beta thyroid hormone receptor (TR) gene expression during auditory neurogenesis: evidence for TR isoform-specific transcriptional regulation in vivoResistance to thyroid hormone is modulated in vivo by the nuclear receptor corepressor (NCOR1).Germline and somatic thyroid hormone receptor mutations in man.Identical mutations in unrelated families with generalized resistance to thyroid hormone occur in cytosine-guanine-rich areas of the thyroid hormone receptor beta gene. Analysis of 15 familiesCell type-dependent modulation of the dominant negative action of human mutant thyroid hormone beta 1 receptorsThyroid hormone resistance syndrome caused by heterozygous A317T mutation in thyroid hormone receptor β gene: Report of one Chinese pedigree and review of the literature.Mutations of CpG dinucleotides located in the triiodothyronine (T3)-binding domain of the thyroid hormone receptor (TR) beta gene that appears to be devoid of natural mutations may not be detected because they are unlikely to produce the clinical phThyroid hormone resistance syndrome manifests as an aberrant interaction between mutant T3 receptors and transcriptional corepressors.A clinician's guide to understanding resistance to thyroid hormone due to receptor mutations in the TRα and TRβ isoforms.Neonatal thyrotoxicosis and maternal infertility in thyroid hormone resistance due to a mutation in the TRbeta gene (M313T).Thyroid hormone response elements differentially modulate the interactions of thyroid hormone receptors with two receptor binding domains in the steroid receptor coactivator-1.Regulation of the human TRH (hTRH) gene by human thyroid hormone receptor beta 1 (hTR beta 1) mutants.
P2860
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P2860
New insights on the mechanism(s) of the dominant negative effect of mutant thyroid hormone receptor in generalized resistance to thyroid hormone.
description
1992 nî lūn-bûn
@nan
1992年の論文
@ja
1992年論文
@yue
1992年論文
@zh-hant
1992年論文
@zh-hk
1992年論文
@zh-mo
1992年論文
@zh-tw
1992年论文
@wuu
1992年论文
@zh
1992年论文
@zh-cn
name
New insights on the mechanism( ...... resistance to thyroid hormone.
@ast
New insights on the mechanism( ...... resistance to thyroid hormone.
@en
type
label
New insights on the mechanism( ...... resistance to thyroid hormone.
@ast
New insights on the mechanism( ...... resistance to thyroid hormone.
@en
prefLabel
New insights on the mechanism( ...... resistance to thyroid hormone.
@ast
New insights on the mechanism( ...... resistance to thyroid hormone.
@en
P2093
P2860
P356
P1476
New insights on the mechanism( ...... resistance to thyroid hormone
@en
P2093
P2860
P304
P356
10.1172/JCI116058
P407
P50
P577
1992-11-01T00:00:00Z