Stearoyl gemcitabine nanoparticles overcome resistance related to the over-expression of ribonucleotide reductase subunit M1.
about
Defective hCNT1 transport contributes to gemcitabine chemoresistance in ovarian cancer subtypes: overcoming transport defects using a nanoparticle approach.A Potent Chemotherapeutic Strategy with Eg5 Inhibitor against Gemcitabine Resistant Bladder Cancer.Synthesis and in vitro evaluation of novel lipophilic monophosphorylated gemcitabine derivatives and their nanoparticles.The effect of the acid-sensitivity of 4-(N)-stearoyl gemcitabine-loaded micelles on drug resistance caused by RRM1 overexpression.Stearoyl gemcitabine nanoparticles overcome obesity-induced cancer cell resistance to gemcitabine in a mouse postmenopausal breast cancer model.Silencing of ribonucleotide reductase subunit M1 potentiates the antitumor activity of gemcitabine in resistant cancer cells.Just getting into cells is not enough: mechanisms underlying 4-(N)-stearoyl gemcitabine solid lipid nanoparticle's ability to overcome gemcitabine resistance caused by RRM1 overexpression.Overcoming nucleoside analog chemoresistance of pancreatic cancer: a therapeutic challenge.Cellular uptake and anti-tumor activity of gemcitabine conjugated with new amphiphilic cell penetrating peptidesSynthesis, Characterization, and In Vitro and In Vivo Evaluations of 4-(N)-Docosahexaenoyl 2', 2'-Difluorodeoxycytidine with Potent and Broad-Spectrum Antitumor Activity.An innovative hydrogel of gemcitabine-loaded lipid nanocapsules: when the drug is a key player of the nanomedicine structure.Lipid-Drug Conjugate for Enhancing Drug Delivery.Oral 4-(N)-stearoyl gemcitabine nanoparticles inhibit tumor growth in mouse models.Pancreatic Cancer Chemoresistance to Gemcitabine.Novel Gemcitabine Conjugated Albumin Nanoparticles: a Potential Strategy to Enhance Drug Efficacy in Pancreatic Cancer Treatment.Overcoming tumor cell chemoresistance using nanoparticles: lysosomes are beneficial for (stearoyl) gemcitabine-incorporated solid lipid nanoparticles.
P2860
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P2860
Stearoyl gemcitabine nanoparticles overcome resistance related to the over-expression of ribonucleotide reductase subunit M1.
description
2011 nî lūn-bûn
@nan
2011年の論文
@ja
2011年論文
@yue
2011年論文
@zh-hant
2011年論文
@zh-hk
2011年論文
@zh-mo
2011年論文
@zh-tw
2011年论文
@wuu
2011年论文
@zh
2011年论文
@zh-cn
name
Stearoyl gemcitabine nanoparti ...... cleotide reductase subunit M1.
@ast
Stearoyl gemcitabine nanoparti ...... cleotide reductase subunit M1.
@en
type
label
Stearoyl gemcitabine nanoparti ...... cleotide reductase subunit M1.
@ast
Stearoyl gemcitabine nanoparti ...... cleotide reductase subunit M1.
@en
prefLabel
Stearoyl gemcitabine nanoparti ...... cleotide reductase subunit M1.
@ast
Stearoyl gemcitabine nanoparti ...... cleotide reductase subunit M1.
@en
P2093
P2860
P1476
Stearoyl gemcitabine nanoparti ...... cleotide reductase subunit M1.
@en
P2093
Brian R Sloat
Dharmika S P Lansakara-P
Michael A Sandoval
Woon-Gye Chung
Zhengrong Cui
P2860
P304
P356
10.1016/J.JCONREL.2011.08.004
P407
P577
2011-08-07T00:00:00Z