A46, a benzothiophene-derived compound, suppresses Jak2-mediated pathologic cell growth

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A46, a benzothiophene-derived compound, suppresses Jak2-mediated pathologic cell growth

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2011 nî lūn-bûn

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2011年の論文

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2011年論文

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2011年論文

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2011年論文

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2011年論文

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2011年論文

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A46, a benzothiophene-derived compound, suppresses Jak2-mediated pathologic cell growth

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A46, a benzothiophene-derived compound, suppresses Jak2-mediated pathologic cell growth

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A46, a benzothiophene-derived compound, suppresses Jak2-mediated pathologic cell growth

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A46, a benzothiophene-derived compound, suppresses Jak2-mediated pathologic cell growth

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A46, a benzothiophene-derived compound, suppresses Jak2-mediated pathologic cell growth

@ast

A46, a benzothiophene-derived compound, suppresses Jak2-mediated pathologic cell growth

@en

P1476

A46, a benzothiophene-derived compound, suppresses Jak2-mediated pathologic cell growth

@en

P2093

Andrew T Magis

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Annet Kirabo

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Anurima Majumder

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György M Keseru

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Kirpal S Bisht

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Nicholas C Figueroa

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Peter P Sayeski

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Rebekah Baskin

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Robert W Allan

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Sung O Park

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P2860

Jak2 deficiency defines an essential developmental checkpoint in definitive hematopoiesis

JAK2 exon 12 mutations in polycythemia vera and idiopathic erythrocytosis

A unique clonal JAK2 mutation leading to constitutive signalling causes polycythaemia vera

Fusion of TEL, the ETS-variant gene 6 (ETV6), to the receptor-associated kinase JAK2 as a result of t(9;12) in a lymphoid and t(9;15;12) in a myeloid leukemia

A TEL-JAK2 fusion protein with constitutive kinase activity in human leukemia

Jak2 is essential for signaling through a variety of cytokine receptors

Caspase cleaved BID targets mitochondria and is required for cytochrome c release, while BCL-XL prevents this release but not tumor necrosis factor-R1/Fas death

Activating mutation in the tyrosine kinase JAK2 in polycythemia vera, essential thrombocythemia, and myeloid metaplasia with myelofibrosis

A gain-of-function mutation of JAK2 in myeloproliferative disorders

Acquired mutation of the tyrosine kinase JAK2 in human myeloproliferative disorders

P304

22-34

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P31

scholarly article

P356

10.1016/J.EXPHEM.2011.10.003

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P433

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P478

http://www.w3.org/2001/XMLSchema#string

P577

2011-10-20T00:00:00Z

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P5875

51735347

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P698

22019628

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P932

3237899

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