Plexin B1 is repressed by oncogenic B-Raf signaling and functions as a tumor suppressor in melanoma cells
about
Structure of Mediator of RhoA-Dependent Invasion (MRDI) Explains Its Dual Function as a Metabolic Enzyme and a Mediator of Cell InvasionRaf kinases in cancer-roles and therapeutic opportunitiesAn integrative characterization of recurrent molecular aberrations in glioblastoma genomes.Skin as a living coloring book: how epithelial cells create patterns of pigmentation.The Rho GTPase Rnd1 suppresses mammary tumorigenesis and EMT by restraining Ras-MAPK signalling.Clinically relevant genes and regulatory pathways associated with NRASQ61 mutations in melanoma through an integrative genomics approach.Epigenetic reprogramming by tumor-derived EZH2 gain-of-function mutations promotes aggressive 3D cell morphologies and enhances melanoma tumor growthRegulation of behaviorally associated gene networks in worker honey bee ovaries.MicroRNA expression profiling predicts clinical outcome of carboplatin/paclitaxel-based therapy in metastatic melanoma treated on the ECOG-ACRIN trial E2603.ErbB-2 signals through Plexin-B1 to promote breast cancer metastasis.The role of semaphorins and their receptors in gliomasPlexin B1 inhibits MET through direct association and regulates Shp2 expression in melanocytesOncogenic B-Raf signaling in melanoma cells controls a network of microRNAs with combinatorial functions.Plexin B1 suppresses c-Met in melanoma: a role for plexin B1 as a tumor-suppressor protein through regulation of c-Met.Experimental validation of 5 in-silico predicted glioma biomarkers.Roles of Sema4D and Plexin-B1 in tumor progressionc-MET as a potential therapeutic target and biomarker in cancer.Plexin structures are coming: opportunities for multilevel investigations of semaphorin guidance receptors, their cell signaling mechanisms, and functions.Semaphorin receptors meet receptor tyrosine kinases on the way of tumor progression.Plexin-B1 indirectly affects glioma invasiveness and angiogenesis by regulating the RhoA/αvβ3 signaling pathway and SRPK1.MicroRNAs in melanoma development and resistance to target therapy.The neural guidance receptor Plexin C1 delays melanoma progression.Cancer stem-like cells enriched with CD29 and CD44 markers exhibit molecular characteristics with epithelial-mesenchymal transition in squamous cell carcinoma.Plexin B1 inhibits integrin-dependent pp125FAK and Rho activity in melanoma.A role for class 3 semaphorins in prostate cancer.Sema4D, the ligand for Plexin B1, suppresses c-Met activation and migration and promotes melanocyte survival and growth.Function of mutant and wild-type plexinb1 in prostate cancer cells.PEG-peptide hydrogels reveal differential effects of matrix microenvironmental cues on melanoma drug sensitivity.
P2860
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P2860
Plexin B1 is repressed by oncogenic B-Raf signaling and functions as a tumor suppressor in melanoma cells
description
2009 nî lūn-bûn
@nan
2009年の論文
@ja
2009年論文
@yue
2009年論文
@zh-hant
2009年論文
@zh-hk
2009年論文
@zh-mo
2009年論文
@zh-tw
2009年论文
@wuu
2009年论文
@zh
2009年论文
@zh-cn
name
Plexin B1 is repressed by onco ...... r suppressor in melanoma cells
@ast
Plexin B1 is repressed by onco ...... r suppressor in melanoma cells
@en
type
label
Plexin B1 is repressed by onco ...... r suppressor in melanoma cells
@ast
Plexin B1 is repressed by onco ...... r suppressor in melanoma cells
@en
prefLabel
Plexin B1 is repressed by onco ...... r suppressor in melanoma cells
@ast
Plexin B1 is repressed by onco ...... r suppressor in melanoma cells
@en
P2093
P2860
P356
P1433
P1476
Plexin B1 is repressed by onco ...... r suppressor in melanoma cells
@en
P2093
G M Argast
P2860
P2888
P304
P356
10.1038/ONC.2009.133
P407
P577
2009-06-01T00:00:00Z