A nuclear protein tyrosine phosphatase is required for the inactivation of Stat1.
about
Distinct roles of the NH2- and COOH-terminal domains of the protein inhibitor of activated signal transducer and activator of transcription (STAT) 1 (PIAS1) in cytokine-induced PIAS1-Stat1 interactionNucleocytoplasmic translocation of Stat1 is regulated by a leucine-rich export signal in the coiled-coil domainTYK2 and JAK2 are substrates of protein-tyrosine phosphatase 1BA novel disrupter of telomere silencing 1-like (DOT1L) interaction is required for signal transducer and activator of transcription 1 (STAT1)-activated gene expressionIdentification of a nuclear Stat1 protein tyrosine phosphataseSTAT-1 and c-Fos interaction in nitric oxide synthase-2 gene activationPrinciples of interleukin (IL)-6-type cytokine signalling and its regulationGATA-3 transcriptional imprinting in Th2 lymphocytes: a mathematical modelStat1-vitamin D receptor interactions antagonize 1,25-dihydroxyvitamin D transcriptional activity and enhance stat1-mediated transcription.A Drosophila PIAS homologue negatively regulates stat92ETranscriptional regulation by STAT1 and STAT2 in the interferon JAK-STAT pathwaySTAT3-dependent enhanceosome assembly and disassembly: synergy with GR for full transcriptional increase of the alpha 2-macroglobulin geneSignal transducers and activators of transcription as regulators of growth, apoptosis and breast development.Signaling by STATsInborn errors of human STAT1: allelic heterogeneity governs the diversity of immunological and infectious phenotypesFER kinase activation of Stat3 is determined by the N-terminal sequenceArginine methylation of STAT1 regulates its dephosphorylation by T cell protein tyrosine phosphataseExpression of suppressors of cytokine signaling during liver regenerationCyanidin-3-glucoside suppresses cytokine-induced inflammatory response in human intestinal cells: comparison with 5-aminosalicylic acidRegulation of STAT1 nuclear export by Jak1SHP2 is overexpressed and inhibits pSTAT1-mediated APM component expression, T-cell attracting chemokine secretion, and CTL recognition in head and neck cancer cells.Stat3 isoforms, alpha and beta, demonstrate distinct intracellular dynamics with prolonged nuclear retention of Stat3beta mapping to its unique C-terminal end.Proinflammatory stem cell signaling in cardiac ischemiaHuman cytomegalovirus IE1 protein elicits a type II interferon-like host cell response that depends on activated STAT1 but not interferon-γInterferon alpha activates NF-kappaB in JAK1-deficient cells through a TYK2-dependent pathway.Implications of an antiparallel dimeric structure of nonphosphorylated STAT1 for the activation-inactivation cycle.The role of Stat5a and Stat5b in signaling by IL-2 family cytokines.Modulation of STAT signaling by STAT-interacting proteins.Pharmaceutical intervention in the JAK/STAT signaling pathway.STAT1 from the cell membrane to the DNA.Regulated nuclear import of the STAT1 transcription factor by direct binding of importin-alphaActivation of STAT proteins and growth control.Identification of nucleocytoplasmic cycling as a remote sensor in cellular signaling by databased modeling.Two glutamic acid residues in the DNA-binding domain are engaged in the release of STAT1 dimers from DNA.The amino-terminal extensions of the longer Sendai virus C proteins modulate pY701-Stat1 and bulk Stat1 levels independently of interferon signaling.T lymphocyte activation--an inside overview.Elucidating the crosstalk mechanism between IFN-gamma and IL-6 via mathematical modelling.Ebola virus VP24 binds karyopherin alpha1 and blocks STAT1 nuclear accumulationNuclear export signal located within theDNA-binding domain of the STAT1transcription factor.Promoter occupancy of STAT1 in interferon responses is regulated by processive transcription.
P2860
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P2860
A nuclear protein tyrosine phosphatase is required for the inactivation of Stat1.
description
1999 nî lūn-bûn
@nan
1999年の論文
@ja
1999年論文
@yue
1999年論文
@zh-hant
1999年論文
@zh-hk
1999年論文
@zh-mo
1999年論文
@zh-tw
1999年论文
@wuu
1999年论文
@zh
1999年论文
@zh-cn
name
A nuclear protein tyrosine phosphatase is required for the inactivation of Stat1.
@ast
A nuclear protein tyrosine phosphatase is required for the inactivation of Stat1.
@en
type
label
A nuclear protein tyrosine phosphatase is required for the inactivation of Stat1.
@ast
A nuclear protein tyrosine phosphatase is required for the inactivation of Stat1.
@en
prefLabel
A nuclear protein tyrosine phosphatase is required for the inactivation of Stat1.
@ast
A nuclear protein tyrosine phosphatase is required for the inactivation of Stat1.
@en
P2860
P356
P1476
A nuclear protein tyrosine phosphatase is required for the inactivation of Stat1.
@en
P2093
J E Darnell
R L Haspel
P2860
P304
10188-10193
P356
10.1073/PNAS.96.18.10188
P407
P577
1999-08-01T00:00:00Z