Granzyme A Is Required for Regulatory T-Cell Mediated Prevention of Gastrointestinal Graft-versus-Host Disease

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2015 nî lūn-bûn

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2015年の論文

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2015年論文

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2015年論文

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2015年論文

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2015年論文

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2015年論文

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2015年论文

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2015年论文

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2015年论文

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name

Granzyme A Is Required for Reg ...... inal Graft-versus-Host Disease

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Granzyme A Is Required for Reg ...... inal Graft-versus-Host Disease

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type

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label

Granzyme A Is Required for Reg ...... inal Graft-versus-Host Disease

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Granzyme A Is Required for Reg ...... inal Graft-versus-Host Disease

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Granzyme A Is Required for Reg ...... inal Graft-versus-Host Disease

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Granzyme A Is Required for Reg ...... inal Graft-versus-Host Disease

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P1476

Granzyme A Is Required for Reg ...... inal Graft-versus-Host Disease

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P2093

Anke Franzke

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Christina Alter

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Olivia Kershaw

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Sarvari Velaga

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Sya N Ukena

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Ulrike Dringenberg

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P2860

FOXP3+ regulatory T cells in the human immune system

Mouse granzyme A induces a novel death with writhing morphology that is mechanistically distinct from granzyme B-induced apoptosis

Granzyme B is not required for regulatory T cell-mediated suppression of graft-versus-host disease.

Selective regulation of apoptosis: the cytotoxic lymphocyte serpin proteinase inhibitor 9 protects against granzyme B-mediated apoptosis without perturbing the Fas cell death pathway

Tregs prevent GVHD and promote immune reconstitution in HLA-haploidentical transplantation.

Cutting edge: contact-mediated suppression by CD4+CD25+ regulatory cells involves a granzyme B-dependent, perforin-independent mechanism.

CD4(+)CD25(+) immunoregulatory T Cells: new therapeutics for graft-versus-host disease

Human T regulatory cells can use the perforin pathway to cause autologous target cell death.

Regulatory T cells expressing granzyme B play a critical role in controlling lung inflammation during acute viral infection.

Donor-type CD4(+)CD25(+) regulatory T cells suppress lethal acute graft-versus-host disease after allogeneic bone marrow transplantation.

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e0124927

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scholarly article

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10.1371/JOURNAL.PONE.0124927

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English

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P478

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Julian Pardo

P577

2015-04-30T00:00:00Z

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P5875

277360709

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P698

25928296

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P932

4415808

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