The insulin receptor isoform exon 11- (IR-A) in cancer and other diseases: a review.
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The insulin receptor is essential for virus-induced tumorigenesis of Kaposi's sarcomaTargeting the insulin-like growth factor pathway in hepatocellular carcinomaExogenous administration of protease-resistant, non-matrix-binding IGFBP-2 inhibits tumour growth in a murine model of breast cancer.Insulin-like growth factor binding proteins: a structural perspective.Decreased expression of insulin-like growth factor binding protein 6 is associated with gastric adenocarcinoma prognosis.Mechanisms of activation of receptor tyrosine kinases: monomers or dimers.RACK1 recruits STAT3 specifically to insulin and insulin-like growth factor 1 receptors for activation, which is important for regulating anchorage-independent growth.Reduced insulin-like growth factor I receptor and altered insulin receptor isoform mRNAs in normal mucosa predict colorectal adenoma risk.Structure of the insulin receptor ectodomain reveals a folded-over conformation.Identification of MBNL1 and MBNL3 domains required for splicing activation and repression.Overexpression of the insulin receptor isoform A promotes endometrial carcinoma cell growth.Insulin is a potent myeloma cell growth factor through insulin/IGF-1 hybrid receptor activation.Aberrant liver insulin receptor isoform a expression normalises with remission of type 2 diabetes after gastric bypass surgery.Understanding the mechanism of insulin and insulin-like growth factor (IGF) receptor activation by IGF-II.Prognostic impact of insulin receptor expression on survival of patients with nonsmall cell lung cancer.Insulin resistance and cancer risk: an overview of the pathogenetic mechanisms.IGF1 and IGF2 specificities to the two insulin receptor isoforms are determined by insulin receptor amino acid 718.Role of insulin receptor and balance in insulin receptor isoforms A and B in regulation of apoptosis in simian virus 40-immortalized neonatal hepatocytesIGF2: epigenetic regulation and role in development and disease.Targeting the insulin-like growth factor-1 receptor in human cancer.Insulin-like growth factor: current concepts and new developments in cancer therapy.Tissue-specificity and ethnic diversity in obesity-related risk of cancer may be explained by variability in insulin response and insulin signaling pathways.Insulin-like growth factor receptor type I as a target for cancer therapy.Small molecule inhibitors of the IGF-1R/IR axis for the treatment of cancer.Diabetes and cancer relationships.Equine insulin receptor and insulin-like growth factor-1 receptor expression in digital lamellar tissue and insulin target tissues.Insulin receptor alternative splicing is regulated by insulin signaling and modulates beta cell survival.Insulin-like growth factor axis targeting in cancer and tumour angiogenesis - the missing link.Targeting the insulin-like growth factor pathway in rhabdomyosarcomas: rationale and future perspectives.Novel role for insulin as an autocrine growth factor for malignant brain tumour cells.Inhibition of insulin receptor isoform-A signalling restores sensitivity to gefitinib in previously de novo resistant colon cancer cells.A novel approach to identify two distinct receptor binding surfaces of insulin-like growth factor II.Characterization of insulin/IGF hybrid receptors: contributions of the insulin receptor L2 and Fn1 domains and the alternatively spliced exon 11 sequence to ligand binding and receptor activation.New target genes for the peroxisome proliferator-activated receptor-γ (PPARγ) antitumour activity: Perspectives from the insulin receptorPTP1B deficiency increases glucose uptake in neonatal hepatocytes: involvement of IRA/GLUT2 complexes.Evolution of the insulin receptor family and receptor isoform expression in vertebrates.Sex-Specific Associations of Maternal Gestational Glycemia with Hormones in Umbilical Cord Blood at Delivery.Targeted delivery of insulin-modified immunoliposomes in vivo.Loss of responsiveness to IGF-I in cells with reduced cathepsin L expression levels.The Role of Insulin Receptor Isoforms in Diabetes and Its Metabolic and Vascular Complications.
P2860
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P2860
The insulin receptor isoform exon 11- (IR-A) in cancer and other diseases: a review.
description
2003 nî lūn-bûn
@nan
2003年の論文
@ja
2003年論文
@yue
2003年論文
@zh-hant
2003年論文
@zh-hk
2003年論文
@zh-mo
2003年論文
@zh-tw
2003年论文
@wuu
2003年论文
@zh
2003年论文
@zh-cn
name
The insulin receptor isoform exon 11- (IR-A) in cancer and other diseases: a review.
@ast
The insulin receptor isoform exon 11- (IR-A) in cancer and other diseases: a review.
@en
type
label
The insulin receptor isoform exon 11- (IR-A) in cancer and other diseases: a review.
@ast
The insulin receptor isoform exon 11- (IR-A) in cancer and other diseases: a review.
@en
prefLabel
The insulin receptor isoform exon 11- (IR-A) in cancer and other diseases: a review.
@ast
The insulin receptor isoform exon 11- (IR-A) in cancer and other diseases: a review.
@en
P2093
P356
P1476
The insulin receptor isoform exon 11- (IR-A) in cancer and other diseases: a review
@en
P2093
P304
P356
10.1055/S-2004-814157
P577
2003-11-01T00:00:00Z