Systemic administration of combinatorial dsiRNAs via nanoparticles efficiently suppresses HIV-1 infection in humanized mice
about
Engineering HIV-1-resistant T-cells from short-hairpin RNA-expressing hematopoietic stem/progenitor cells in humanized BLT miceNanostructures for the Inhibition of Viral InfectionsAnti-HIV-1 nanotherapeutics: promises and challenges for the futureStudies of retroviral infection in humanized miceFighting against kidney diseases with small interfering RNA: opportunities and challengesNew generation humanized mice for virus research: comparative aspects and future prospectsGene therapy strategies for HIV/AIDS: preclinical modeling in humanized miceAchieving HIV-1 Control through RNA-Directed Gene RegulationProgress toward in vivo use of siRNAs-IICationic nanoparticles directly bind angiotensin-converting enzyme 2 and induce acute lung injury in miceMassive palmitoylation-dependent endocytosis during reoxygenation of anoxic cardiac muscle.A DNA dual lock-and-key strategy for cell-subtype-specific siRNA delivery.Genome-wide profiling identified a set of miRNAs that are differentially expressed in glioblastoma stem cells and normal neural stem cells.Novel RNA oligonucleotide improves liver function and inhibits liver carcinogenesis in vivo.Current humanized mouse models for studying human immunology and HIV-1 immuno-pathogenesis.Combinatorial anti-HIV gene therapy: using a multipronged approach to reach beyond HAARTRNA-based TWIST1 inhibition via dendrimer complex to reduce breast cancer cell metastasis.Cell-specific RNA aptamer against human CCR5 specifically targets HIV-1 susceptible cells and inhibits HIV-1 infectivity.RNA interference approaches for treatment of HIV-1 infectionInhibition of hepatitis C virus replication by intracellular delivery of multiple siRNAs by nanosomes.Functional in vivo delivery of multiplexed anti-HIV-1 siRNAs via a chemically synthesized aptamer with a sticky bridgeDownregulation of TLX induces TET3 expression and inhibits glioblastoma stem cell self-renewal and tumorigenesis.Selection of 2'-deoxy-2'-fluoroarabinonucleotide (FANA) aptamers that bind HIV-1 reverse transcriptase with picomolar affinityBiomaterial Strategies for Immunomodulation.A novel dendritic nanocarrier of polyamidoamine-polyethylene glycol-cyclic RGD for "smart" small interfering RNA delivery and in vitro antitumor effects by human ether-à-go-go-related gene silencing in anaplastic thyroid carcinoma cellsU1 Adaptor Oligonucleotides Targeting BCL2 and GRM1 Suppress Growth of Human Melanoma Xenografts In VivoEfficient inhibition of human immunodeficiency virus replication using novel modified microRNA-30a targeting 3'-untranslated region transcripts.Antiviral Stratagems Against HIV-1 Using RNA Interference (RNAi) Technology.Nanoparticle characterization: state of the art, challenges, and emerging technologies.Functional inhibition of chemokine receptor CCR2 by dicer-substrate-siRNA prevents pain developmentAptamer-based therapeutics: new approaches to combat human viral diseasesPromoter Targeting shRNA Suppresses HIV-1 Infection In vivo Through Transcriptional Gene Silencing.HIV-1 immunopathogenesis in humanized mouse models.Nanoparticle-Based Delivery of RNAi Therapeutics: Progress and Challenges.Dendrimers as potential therapeutic tools in HIV inhibition.Advances in siRNA delivery to T-cells: potential clinical applications for inflammatory disease, cancer and infection.Delivery of RNAi therapeutics: work in progress.New hope for eradication of HIV from the body: the role of polymeric nanomedicines in HIV/AIDS pharmacotherapy.Treatment of Liver Cancer by C/EBPA saRNA.Magnetic nanoparticles: Applications in gene delivery and gene therapy.
P2860
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P2860
Systemic administration of combinatorial dsiRNAs via nanoparticles efficiently suppresses HIV-1 infection in humanized mice
description
2011 nî lūn-bûn
@nan
2011年の論文
@ja
2011年論文
@yue
2011年論文
@zh-hant
2011年論文
@zh-hk
2011年論文
@zh-mo
2011年論文
@zh-tw
2011年论文
@wuu
2011年论文
@zh
2011年论文
@zh-cn
name
Systemic administration of com ...... -1 infection in humanized mice
@ast
Systemic administration of com ...... -1 infection in humanized mice
@en
type
label
Systemic administration of com ...... -1 infection in humanized mice
@ast
Systemic administration of com ...... -1 infection in humanized mice
@en
prefLabel
Systemic administration of com ...... -1 infection in humanized mice
@ast
Systemic administration of com ...... -1 infection in humanized mice
@en
P2093
P2860
P356
P1433
P1476
Systemic administration of com ...... -1 infection in humanized mice
@en
P2093
C Preston Neff
David D Smith
Haitang Li
Jane Zhang
Jiehua Zhou
John J Rossi
Piotr Swiderski
Ramesh Akkina
P2860
P304
P356
10.1038/MT.2011.207
P577
2011-09-27T00:00:00Z