The role of signal transducer and activator of transcription factors in leukemogenesis.
about
Transformation of hematopoietic cells and activation of JAK2-V617F by IL-27R, a component of a heterodimeric type I cytokine receptorHsp90 Inhibitors for the Treatment of Chronic Myeloid LeukemiaPhase I study of OPB-51602, an oral inhibitor of signal transducer and activator of transcription 3, in patients with relapsed/refractory hematological malignancies.SEL120-34A is a novel CDK8 inhibitor active in AML cells with high levels of serine phosphorylation of STAT1 and STAT5 transactivation domainsSignal transducer and activator of transcription 3 (STAT3) gene polymorphisms are associated with treatment outcomes in acute myeloid leukemia.Transforming and tumorigenic activity of JAK2 by fusion to BCR: molecular mechanisms of action of a novel BCR-JAK2 tyrosine-kinase.Unphosphorylated STAT5A stabilizes heterochromatin and suppresses tumor growth.PTP1B suppresses prolactin activation of Stat5 in breast cancer cells.RA-inducible gene-I induction augments STAT1 activation to inhibit leukemia cell proliferationIdentification of Drosophila genes modulating Janus kinase/signal transducer and activator of transcription signal transduction.Canonical and non-canonical JAK-STAT signaling.Comparative analyses of differentially induced T-cell receptor-mediated phosphorylation pathways in T lymphoma cellsSTAT3 mRNA and protein expression in colorectal cancer: effects on STAT3-inducible targets linked to cell survival and proliferationRNA interference as a potential tool in the treatment of leukaemia.FoxO tumor suppressors and BCR-ABL-induced leukemia: a matter of evasion of apoptosis.Reducing the genotoxic potential of retroviral vectors.Stat5 is critical for the development and maintenance of myeloproliferative neoplasm initiated by Nf1 deficiencyInnate immune signaling pathways in animals: beyond reductionism.The erythropoietin receptor: molecular structure and hematopoietic signaling pathways.STAT transcription factors in hematopoiesis and leukemogenesis: opportunities for therapeutic intervention.STAT3 inhibitors: finding a home in lymphoma and leukemia.Caspase-3 and caspase-6 cleave STAT1 in leukemic cellsTargeting STAT5 in hematologic malignancies through inhibition of the bromodomain and extra-terminal (BET) bromodomain protein BRD2.Silibinin inhibits constitutive activation of Stat3, and causes caspase activation and apoptotic death of human prostate carcinoma DU145 cells.Gö6976 is a potent inhibitor of the JAK 2 and FLT3 tyrosine kinases with significant activity in primary acute myeloid leukaemia cells.Identification of human STAT5-dependent gene regulatory elements based on interspecies homology.GLI1 inhibitor GANT61 exhibits antitumor efficacy in T-cell lymphoma cells through down-regulation of p-STAT3 and SOCS3.Stat5 Exerts Distinct, Vital Functions in the Cytoplasm and Nucleus of Bcr-Abl+ K562 and Jak2(V617F)+ HEL Leukemia Cells.Phase 1 and pharmacological trial of OPB-31121, a signal transducer and activator of transcription-3 inhibitor, in patients with advanced hepatocellular carcinoma.The Role of Signal Transducer and Activator of Transcription 3 (STAT3) and Its Targeted Inhibition in Hematological Malignancies
P2860
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P2860
The role of signal transducer and activator of transcription factors in leukemogenesis.
description
2004 nî lūn-bûn
@nan
2004年の論文
@ja
2004年論文
@yue
2004年論文
@zh-hant
2004年論文
@zh-hk
2004年論文
@zh-mo
2004年論文
@zh-tw
2004年论文
@wuu
2004年论文
@zh
2004年论文
@zh-cn
name
The role of signal transducer and activator of transcription factors in leukemogenesis.
@ast
The role of signal transducer and activator of transcription factors in leukemogenesis.
@en
type
label
The role of signal transducer and activator of transcription factors in leukemogenesis.
@ast
The role of signal transducer and activator of transcription factors in leukemogenesis.
@en
prefLabel
The role of signal transducer and activator of transcription factors in leukemogenesis.
@ast
The role of signal transducer and activator of transcription factors in leukemogenesis.
@en
P356
P1476
The role of signal transducer and activator of transcription factors in leukemogenesis.
@en
P2093
D Gary Gilliland
David W Sternberg
P304
P356
10.1200/JCO.2004.10.124
P407
P577
2004-01-01T00:00:00Z