Hypotension, lipodystrophy, and insulin resistance in generalized PPARgamma-deficient mice rescued from embryonic lethality. - Wikidata - awgldk - TriplyDB

Hypotension, lipodystrophy, and insulin resistance in generalized PPARgamma-deficient mice rescued from embryonic lethality.

Hypotension, lipodystrophy, and insulin resistance in generalized PPARgamma-deficient mice rescued from embryonic lethality.

http://www.wikidata.org/entity/Q35629015

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Is the Mouse a Good Model of Human PPARγ-Related Metabolic Diseases?PPARs Link Early Life Nutritional Insults to Later Programmed Hypertension and Metabolic Syndrome Perivascular adipose tissue in vascular function and disease: a review of current research and animal models Smooth Muscle-Targeted Overexpression of Peroxisome Proliferator Activated Receptor-γ Disrupts Vascular Wall Structure and Function Notchless is required for axial skeleton formation in mice Inhibitor of DNA binding 4 (ID4) regulation of adipocyte differentiation and adipose tissue formation in mice PPARγ activation attenuates cold-induced upregulation of thyroid status and brown adipose tissue PGC-1α and D2 Fat storage-inducing transmembrane protein 2 is required for normal fat storage in adipose tissue Increased renin production in mice with deletion of peroxisome proliferator-activated receptor-gamma in juxtaglomerular cells.PPARgamma regulates trophoblast proliferation and promotes labyrinthine trilineage differentiation Systemic PPARγ deletion impairs circadian rhythms of behavior and metabolism.Endothelial and vascular muscle PPARgamma in arterial pressure regulation: lessons from genetic interference and deficiency.Vascular smooth muscle cell-selective peroxisome proliferator-activated receptor-gamma deletion leads to hypotension PPARγ downregulation by TGFß in fibroblast and impaired expression and function in systemic sclerosis: a novel mechanism for progressive fibrogenesis Bioinformatic analysis of gene sets regulated by ligand-activated and dominant-negative peroxisome proliferator-activated receptor gamma in mouse aorta.Proteasomal degradation of retinoid X receptor alpha reprograms transcriptional activity of PPARgamma in obese mice and humans Fighting fat with fat: the expanding field of adipose stem cells.Sex dimorphic actions of rosiglitazone in generalised peroxisome proliferator-activated receptor-gamma (PPAR-gamma)-deficient mice The many facets of PPARgamma: novel insights for the skeleton.Sprouty1 is a critical regulatory switch of mesenchymal stem cell lineage allocation.Myeloid mineralocorticoid receptor controls macrophage polarization and cardiovascular hypertrophy and remodeling in mice.The relationship between peroxisome proliferator-activated receptor-gamma and renin: a human genetics study.Independent stem cell lineages regulate adipose organogenesis and adipose homeostasis Transcriptome analysis of PPARγ target genes reveals the involvement of lysyl oxidase in human placental cytotrophoblast invasion PPARs are a unique set of fatty acid regulated transcription factors controlling both lipid metabolism and inflammation Lipodystrophy: pathophysiology and advances in treatment Adipose triglyceride lipase and hormone-sensitive lipase are involved in fat loss in JunB-deficient mice.The role of perivascular adipose tissue in vasoconstriction, arterial stiffness, and aneurysm.Peroxisome proliferator-activated receptors, metabolic syndrome and cardiovascular disease.Cardiac dysfunction in adipose triglyceride lipase deficiency: treatment with a PPARα agonist.An insulin-sensitizing thiazolidinedione, which minimally activates PPARγ, does not cause bone loss.Wnt signaling activation in adipose progenitors promotes insulin-independent muscle glucose uptake.Peroxisome proliferator-activated receptor γ polymorphism Pro12Ala Is associated with nephropathy in type 2 diabetes: evidence from meta-analysis of 18 studies Smooth muscle protein 22 alpha-Cre is expressed in myeloid cells in mice.Chicken ovalbumin upstream promoter transcription factor II regulates renin gene expression Lipodystrophy, Diabetes and Normal Serum Insulin in PPARγ-Deficient Neonatal Mice.PPAR Signaling in Placental Development and Function.PPAR-gamma in the Cardiovascular System Nonreceptor tyrosine phosphatase Shp2 promotes adipogenesis through inhibition of p38 MAP kinase.Role of PPARs and Retinoid X Receptors in the Regulation of Lung Maturation and Development

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P2860

Hypotension, lipodystrophy, and insulin resistance in generalized PPARgamma-deficient mice rescued from embryonic lethality.

http://www.wikidata.org/entity/Q35629015

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Hypotension, lipodystrophy, an ...... cued from embryonic lethality.

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P2093

Charles Vinson

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Christine Y Ivashchenko

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Damon C Duquaine

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David S Milstone

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Frank C Brosius

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Frank J Gonzalez

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Louis G D'Alecy

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Melissa A Pierre

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Richard M Mortensen

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Sheng Zhong Duan

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P2860

Dominant negative mutations in human PPARgamma associated with severe insulin resistance, diabetes mellitus and hypertension

Deletion of PPARgamma in adipose tissues of mice protects against high fat diet-induced obesity and insulin resistance

PPAR gamma is required for the differentiation of adipose tissue in vivo and in vitro

Transcriptional repression of atherogenic inflammation: modulation by PPARdelta

APC-dependent suppression of colon carcinogenesis by PPARgamma

Collecting duct-specific knockout of endothelin-1 causes hypertension and sodium retention

Muscle-specific Pparg deletion causes insulin resistance

Opposite effects of androgens and estrogens on adipogenesis in rat preadipocytes: evidence for sex and site-related specificities and possible involvement of insulin-like growth factor 1 receptor and peroxisome proliferator-activated receptor gamma2

Stimulation of adipogenesis in fibroblasts by PPAR gamma 2, a lipid-activated transcription factor

mPPAR gamma 2: tissue-specific regulator of an adipocyte enhancer

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812-822

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10.1172/JCI28859

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3

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117

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17304352

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