NF-kappa B prevents beta cell death and autoimmune diabetes in NOD mice - Wikidata - awgldk - TriplyDB

NF-kappa B prevents beta cell death and autoimmune diabetes in NOD mice

NF-kappa B prevents beta cell death and autoimmune diabetes in NOD mice

http://www.wikidata.org/entity/Q35629489

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Damage associated molecular pattern molecules From estrogen-centric to aging and oxidative stress: a revised perspective of the pathogenesis of osteoporosis Resolving the conundrum of islet transplantation by linking metabolic dysregulation, inflammation, and immune regulation.Role and mechanism of pancreatic β-cell death in diabetes: The emerging role of autophagy.Inflammatory response in islet transplantation.A20 Inhibits β-Cell Apoptosis by Multiple Mechanisms and Predicts Residual β-Cell Function in Type 1 Diabetes.Differential expression of islet glutaredoxin 1 and 5 with high reactive oxygen species production in a mouse model of diabesity Regulation of CCAAT/enhancer-binding protein homologous protein (CHOP) expression by interleukin-1 beta in pancreatic beta cells Mixed lineage kinase-3 stabilizes and functionally cooperates with TRIBBLES-3 to compromise mitochondrial integrity in cytokine-induced death of pancreatic beta cells Sulfuretin protects against cytokine-induced beta-cell damage and prevents streptozotocin-induced diabetes.Lipopolysaccharides impair insulin gene expression in isolated islets of Langerhans via Toll-Like Receptor-4 and NF-κB signalling.microRNA-21-induced dissociation of PDCD4 from rictor contributes to Akt-IKKβ-mTORC1 axis to regulate renal cancer cell invasion.Disruption of hepatocyte growth factor/c-Met signaling enhances pancreatic beta-cell death and accelerates the onset of diabetes Small-molecule inhibition of inflammatory β-cell death.Role of innate immunity in diabetes and metabolism: recent progress in the study of inflammasomes.The microRNA-21-PDCD4 axis prevents type 1 diabetes by blocking pancreatic beta cell death.Polyphenols isolated from Broussonetia kazinoki prevent cytokine-induced β-cell damage and the development of type 1 diabetes Role of autophagy in diabetes and endoplasmic reticulum stress of pancreatic β-cells.TNFalpha in the pathogenesis of diabetes-induced embryopathies: functions and targets.Alterations in microRNA expression contribute to fatty acid-induced pancreatic beta-cell dysfunction.Divergent effects of sulforaphane on basal and glucose-stimulated insulin secretion in β-cells: role of reactive oxygen species and induction of endogenous antioxidants Expression of the NH(2)-terminal fragment of RasGAP in pancreatic beta-cells increases their resistance to stresses and protects mice from diabetes.The pancreatic β cell and type 1 diabetes: innocent bystander or active participant?Interleukin-1 beta targeted therapy for type 2 diabetes.Anti-inflammatory therapy in type 1 diabetes.Zinc and insulin in pancreatic beta-cells.Role of pancreatic β-cell death and inflammation in diabetes.Autophagy deficiency in beta cells leads to compromised unfolded protein response and progression from obesity to diabetes in mice.The non-canonical NF-κB pathway is induced by cytokines in pancreatic beta cells and contributes to cell death and proinflammatory responses in vitro.Neutralization Versus Reinforcement of Proinflammatory Cytokines to Arrest Autoimmunity in Type 1 Diabetes.Omega-3 fatty acids in prevention of diabetic retinopathy.Thiazolidinediones protect mouse pancreatic β-cells directly from cytokine-induced cytotoxicity through PPARγ-dependent mechanisms.Imatinib mesylate reduces endoplasmic reticulum stress and induces remission of diabetes in db/db mice.Tissue factor/factor VIIa signalling promotes cytokine-induced beta cell death and impairs glucose-stimulated insulin secretion from human pancreatic islets.Uncoupling protein-2 increases nitric oxide production and TNFAIP3 pathway activation in pancreatic islets.Deficiency of Nuclear Factor-κB c-Rel Accelerates the Development of Autoimmune Diabetes in NOD Mice.Overexpression of the nuclear factor-κB subunit c-Rel protects against human islet cell death in vitro.Improved intraportal islet transplantation outcome by systemic IKK-beta inhibition: NF-κB activity in pancreatic islets depends on oxygen availability.IKKβ inhibition prevents fat-induced beta cell dysfunction in vitro and in vivo in rodents.High CXC Chemokine Ligand 16 (CXCL16) Expression Promotes Proliferation and Metastasis of Lung Cancer via Regulating the NF-κB Pathway.

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NF-kappa B prevents beta cell death and autoimmune diabetes in NOD mice

http://www.wikidata.org/entity/Q35629489

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2007 nî lūn-bûn

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2007年論文

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2007年論文

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2007年論文

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2007年论文

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2007年论文

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2007年论文

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name

NF-kappa B prevents beta cell death and autoimmune diabetes in NOD mice

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NF-kappa B prevents beta cell death and autoimmune diabetes in NOD mice

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type

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NF-kappa B prevents beta cell death and autoimmune diabetes in NOD mice

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NF-kappa B prevents beta cell death and autoimmune diabetes in NOD mice

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prefLabel

NF-kappa B prevents beta cell death and autoimmune diabetes in NOD mice

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NF-kappa B prevents beta cell death and autoimmune diabetes in NOD mice

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PNAS.0610690104

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Proceedings of the National Academy of Sciences of the United States of America

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NF-kappa B prevents beta cell death and autoimmune diabetes in NOD mice

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Hun Sik Kim

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Isabelle Millet

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Ja Young Kim

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Kwang-Won Kim

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Moon-Kyu Lee

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Myoung Sook Han

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Myung-Shik Lee

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Robert S Sherwin

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Sunshin Kim

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P2860

Does nitric oxide mediate autoimmune destruction of beta-cells? Possible therapeutic interventions in IDDM

Mechanisms of beta-cell death in response to double-stranded (ds) RNA and interferon-gamma: dsRNA-dependent protein kinase apoptosis and nitric oxide-dependent necrosis

Dual roles for glucokinase in glucose homeostasis as determined by liver and pancreatic beta cell-specific gene knock-outs using Cre recombinase

Missing pieces in the NF-kappaB puzzle

IKK-beta links inflammation to obesity-induced insulin resistance

TNF- and cancer therapy-induced apoptosis: potentiation by inhibition of NF-kappaB

An essential role for NF-kappaB in preventing TNF-alpha-induced cell death

NF-kappaB antiapoptosis: induction of TRAF1 and TRAF2 and c-IAP1 and c-IAP2 to suppress caspase-8 activation

Local and systemic insulin resistance resulting from hepatic activation of IKK-beta and NF-kappaB

Synergistic activation of NF-kappab and inducible isoform of nitric oxide synthase induction by interferon-gamma and tumor necrosis factor-alpha in INS-1 cells.

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