The Xanthine Derivative KMUP-1 Attenuates Serotonin-Induced Vasoconstriction and K⁺-Channel Inhibitory Activity via the PKC Pathway in Pulmonary Arteries

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Molecular pathogenesis and current pathology of pulmonary hypertension.Xanthine scaffold: scope and potential in drug development

P2860

Q38676413-7B799AE2-9748-4523-A8D8-D77C9C72ABB1 Q57298107-120FBA12-B19C-4EF4-9F80-6196F441735F

P2860

The Xanthine Derivative KMUP-1 Attenuates Serotonin-Induced Vasoconstriction and K⁺-Channel Inhibitory Activity via the PKC Pathway in Pulmonary Arteries

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2015 nî lūn-bûn

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2015年の論文

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2015年論文

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2015年論文

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2015年論文

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2015年論文

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The Xanthine Derivative KMUP-1 ...... Pathway in Pulmonary Arteries

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The Xanthine Derivative KMUP-1 ...... Pathway in Pulmonary Arteries

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The Xanthine Derivative KMUP-1 ...... Pathway in Pulmonary Arteries

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The Xanthine Derivative KMUP-1 ...... Pathway in Pulmonary Arteries

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The Xanthine Derivative KMUP-1 ...... Pathway in Pulmonary Arteries

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The Xanthine Derivative KMUP-1 ...... Pathway in Pulmonary Arteries

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P1476

The Xanthine Derivative KMUP-1 ...... Pathway in Pulmonary Arteries

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P2093

Bin-Nan Wu

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Ing-Jun Chen

http://www.w3.org/2001/XMLSchema#string

Jiunn-Ren Wu

http://www.w3.org/2001/XMLSchema#string

Jong-Hau Hsu

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Jwu-Lai Yeh

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Yu-Wei Liu

http://www.w3.org/2001/XMLSchema#string

Zen-Kong Dai

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P2860

A xanthine-based KMUP-1 with cyclic GMP enhancing and K(+) channels opening activities in rat aortic smooth muscle

Serotonin inhibits voltage-gated K+ currents in pulmonary artery smooth muscle cells: role of 5-HT2A receptors, caveolin-1, and KV1.5 channel internalization

5-hydroxytryptamine and the pulmonary circulation: receptors, transporters and relevance to pulmonary arterial hypertension.

The xanthine derivative KMUP-1 inhibits models of pulmonary artery hypertension via increased NO and cGMP-dependent inhibition of RhoA/Rho kinase

Serotonin regulates voltage-dependent currents in type I(e(A)) and I(i) interneurons of Hermissenda.

KMUP-1 activates BKCa channels in basilar artery myocytes via cyclic nucleotide-dependent protein kinases.

Cellular and molecular pathobiology of pulmonary arterial hypertension.

Caveolins in vascular smooth muscle: form organizing function.

Distinct activity of BK channel β1-subunit in cerebral and pulmonary artery smooth muscle cells.

Modulation of ion channels in pulmonary arterial hypertension.

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633-642

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scholarly article

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10.7150/IJBS.11127

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English

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2015-04-25T00:00:00Z

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277918463

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25999786

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vasoconstriction

P932

4440253

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The Xanthine Derivative KMUP-1 Attenuates Serotonin-Induced Vasoconstriction and K⁺-Channel Inhibitory Activity via the PKC Pathway in Pulmonary Arteries

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P2860

P2860

The Xanthine Derivative KMUP-1 Attenuates Serotonin-Induced Vasoconstriction and K⁺-Channel Inhibitory Activity via the PKC Pathway in Pulmonary Arteries

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type

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P1433

P1476

P2093

P2860

P304

P31

P356

P407

P433

P478

P577

P5875

P698

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P932

P356

P1433

P1476

P2093

P2860

P304

P31

P356

P407

P433

P478

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P698

P921

P932