Self-masking in an intact ERM-merlin protein: an active role for the central alpha-helical domain.
about
Protein phosphatase 1α mediates ceramide-induced ERM protein dephosphorylation: a novel mechanism independent of phosphatidylinositol 4, 5-biphosphate (PIP2) and myosin/ERM phosphataseThe ERM proteins interact with the HOPS complex to regulate the maturation of endosomesModel membranes to shed light on the biochemical and physical properties of ezrin/radixin/moesinStructural Basis for CD44 Recognition by ERM ProteinsUnfurling of the band 4.1, ezrin, radixin, moesin (FERM) domain of the merlin tumor suppressorStructural Basis for Small G Protein Effector Interaction of Ras-related Protein 1 (Rap1) and Adaptor Protein Krev Interaction Trapped 1 (KRIT1)A novel membrane-dependent on/off switch mechanism of talin FERM domain at sites of cell adhesionStructural Basis of the Binding of Merlin FERM Domain to the E3 Ubiquitin Ligase Substrate Adaptor DCAF1Sphingolipid regulation of ezrin, radixin, and moesin proteins family: implications for cell dynamics.MT1-MMP recognition by ERM proteins and its implication in CD44 sheddingMolecular conformation of the full-length tumor suppressor NF2/Merlin--a small-angle neutron scattering studyPhosphatidylinositol 4,5-bisphosphate clusters the cell adhesion molecule CD44 and assembles a specific CD44-Ezrin heterocomplex, as revealed by small angle neutron scatteringOpen conformation of ezrin bound to phosphatidylinositol 4,5-bisphosphate and to F-actin revealed by neutron scatteringOrganizing the cell cortex: the role of ERM proteinsChallenges in homology search: HMMER3 and convergent evolution of coiled-coil regions.Loss of the tumor suppressor gene NF2, encoding merlin, constitutively activates integrin-dependent mTORC1 signaling.The molecular biology of vestibular schwannomas and its association with hearing loss: a review.Structural conservation in band 4.1, ezrin, radixin, moesin (FERM) domains as a guide to identify inhibitors of the proline-rich tyrosine kinase 2.Fluorescence resonance energy transfer analysis of merlin conformational changes.Ezrin activation by LOK phosphorylation involves a PIP2-dependent wedge mechanism.Two dipolar α-helices within hormone-encoding regions of proglucagon are sorting signals to the regulated secretory pathway.Dynamics of ezrin and EBP50 in regulating microvilli on the apical aspect of epithelial cells.Sip1, the Drosophila orthologue of EBP50/NHERF1, functions with the sterile 20 family kinase Slik to regulate Moesin activity.A regulated complex of the scaffolding proteins PDZK1 and EBP50 with ezrin contribute to microvillar organization.Binding of moesin and ezrin to membranes containing phosphatidylinositol (4,5) bisphosphate: a comparative study of the affinity constants and conformational changes.ERM proteins at a glanceThe Pyk2 FERM regulates Pyk2 complex formation and phosphorylationAngiomotin binding-induced activation of Merlin/NF2 in the Hippo pathwayFormation of microvilli and phosphorylation of ERM family proteins by CD43, a potent inhibitor for cell adhesion: cell detachment is a potential cue for ERM phosphorylation and organization of cell morphology.Emerging role for ERM proteins in cell adhesion and migration.FERM domain phosphoinositide binding targets merlin to the membrane and is essential for its growth-suppressive function.Merlin: a tumour suppressor with functions at the cell cortex and in the nucleus.Autosomal Recessive Nonsyndromic Hearing Impairment due to a Novel Deletion in the RDX GeneActivation of moesin, a protein that links actin cytoskeleton to the plasma membrane, occurs by phosphatidylinositol 4,5-bisphosphate (PIP2) binding sequentially to two sites and releasing an autoinhibitory linker.Immune synapse formation requires ZAP-70 recruitment by ezrin and CD43 removal by moesin.Ezrin and moesin function together to promote T cell activation.Juxtanodin is an intrinsically disordered F-actin-binding protein.Local phosphocycling mediated by LOK/SLK restricts ezrin function to the apical aspect of epithelial cellsConundrum, an ARHGAP18 orthologue, regulates RhoA and proliferation through interactions with Moesin.Genetic variations and polymorphisms in the ezrin gene are associated with age-related cataract.
P2860
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P2860
Self-masking in an intact ERM-merlin protein: an active role for the central alpha-helical domain.
description
2006 nî lūn-bûn
@nan
2006年の論文
@ja
2006年論文
@yue
2006年論文
@zh-hant
2006年論文
@zh-hk
2006年論文
@zh-mo
2006年論文
@zh-tw
2006年论文
@wuu
2006年论文
@zh
2006年论文
@zh-cn
name
Self-masking in an intact ERM- ...... central alpha-helical domain.
@ast
Self-masking in an intact ERM- ...... central alpha-helical domain.
@en
type
label
Self-masking in an intact ERM- ...... central alpha-helical domain.
@ast
Self-masking in an intact ERM- ...... central alpha-helical domain.
@en
prefLabel
Self-masking in an intact ERM- ...... central alpha-helical domain.
@ast
Self-masking in an intact ERM- ...... central alpha-helical domain.
@en
P2093
P2860
P1476
Self-masking in an intact ERM- ...... central alpha-helical domain.
@en
P2093
Anthony Bretscher
John J G Tesmer
Kevin Nyberg
Mark R Nance
P Andrew Karplus
Qianzhi Li
Richard Fehon
Rima Kulikauskas
P2860
P304
P356
10.1016/J.JMB.2006.10.075
P407
P577
2006-10-26T00:00:00Z