Human immunodeficiency virus type 1 matrix protein assembles on membranes as a hexamer
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The role of matrix in HIV-1 envelope glycoprotein incorporationThe Structure of Myristoylated Mason-Pfizer Monkey Virus Matrix Protein and the Role of Phosphatidylinositol-(4,5)-Bisphosphate in Its Membrane BindingBiophysical characterization and crystal structure of the Feline Immunodeficiency Virus p15 matrix proteinThe HIVToolbox 2 web system integrates sequence, structure, function and mutation analysisThe structural biology of HIV assembly.Basic residues in the matrix domain and multimerization target murine leukemia virus Gag to the virological synapse.How HIV-1 Gag assembles in cells: Putting together pieces of the puzzle.Opposing mechanisms involving RNA and lipids regulate HIV-1 Gag membrane binding through the highly basic region of the matrix domain.Gag-protease coevolution analyses define novel structural surfaces in the HIV-1 matrix and capsid involved in resistance to Protease InhibitorsTIM-family proteins inhibit HIV-1 release.Electrostatic interactions and binding orientation of HIV-1 matrix studied by neutron reflectivityBinding of calmodulin to the HIV-1 matrix protein triggers myristate exposure.Myristate exposure in the human immunodeficiency virus type 1 matrix protein is modulated by pH.HIV-1 p17 matrix protein interacts with heparan sulfate side chain of CD44v3, syndecan-2, and syndecan-4 proteoglycans expressed on human activated CD4+ T cells affecting tumor necrosis factor alpha and interleukin 2 production.Solution NMR characterizations of oligomerization and dynamics of equine infectious anemia virus matrix protein and its interaction with PIP2.Molecular determinants that regulate plasma membrane association of HIV-1 GagHIV-1 matrix protein binding to RNA.Role of the HIV-1 Matrix Protein in Gag Intracellular Trafficking and Targeting to the Plasma Membrane for Virus Assembly.Biochemical evidence of a role for matrix trimerization in HIV-1 envelope glycoprotein incorporation.Interaction between the human immunodeficiency virus type 1 Gag matrix domain and phosphatidylinositol-(4,5)-bisphosphate is essential for efficient gag membrane binding.Analysis of small molecule ligands targeting the HIV-1 matrix protein-RNA binding site.Discovery of a small-molecule antiviral targeting the HIV-1 matrix protein.Trimer Enhancement Mutation Effects on HIV-1 Matrix Protein Binding Activities.Characterization of the in vitro HIV-1 capsid assembly pathway.HIV-1 matrix organizes as a hexamer of trimers on membranes containing phosphatidylinositol-(4,5)-bisphosphateGlobal rescue of defects in HIV-1 envelope glycoprotein incorporation: implications for matrix structure.Characterization of replication defects induced by mutations in the basic domain and C-terminus of HIV-1 matrix.Role for amino acids 212KLR214 of Ebola virus VP40 in assembly and budding.3D molecular models of whole HIV-1 virions generated with cellPACK.Mutation of critical serine residues in HIV-1 matrix result in an envelope incorporation defect which can be rescued by truncation of the gp41 cytoplasmic tail.
P2860
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P2860
Human immunodeficiency virus type 1 matrix protein assembles on membranes as a hexamer
description
2006 nî lūn-bûn
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2006年の論文
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2006年論文
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2006年論文
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2006年論文
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2006年論文
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name
Human immunodeficiency virus type 1 matrix protein assembles on membranes as a hexamer
@ast
Human immunodeficiency virus type 1 matrix protein assembles on membranes as a hexamer
@en
type
label
Human immunodeficiency virus type 1 matrix protein assembles on membranes as a hexamer
@ast
Human immunodeficiency virus type 1 matrix protein assembles on membranes as a hexamer
@en
prefLabel
Human immunodeficiency virus type 1 matrix protein assembles on membranes as a hexamer
@ast
Human immunodeficiency virus type 1 matrix protein assembles on membranes as a hexamer
@en
P2093
P2860
P356
P1433
P1476
Human immunodeficiency virus type 1 matrix protein assembles on membranes as a hexamer
@en
P2093
Ayna Alfadhli
Dalbinder Colman
Doug Huseby
Eliot Kapit
Eric Barklis
P2860
P304
P356
10.1128/JVI.02122-06
P407
P577
2006-11-15T00:00:00Z