about
Analysis of transient phosphorylation-dependent protein-protein interactions in living mammalian cells using split-TEVImpaired binding of 14-3-3 to C-RAF in Noonan syndrome suggests new approaches in diseases with increased Ras signalingTargeted proteomic analysis of 14-3-3 sigma, a p53 effector commonly silenced in cancerStructural insights of the MLF1/14-3-3 interactionPromotion of importin alpha-mediated nuclear import by the phosphorylation-dependent binding of cargo protein to 14-3-3Regulation of MDMX nuclear import and degradation by Chk2 and 14-3-3.A novel binding factor of 14-3-3beta functions as a transcriptional repressor and promotes anchorage-independent growth, tumorigenicity, and metastasisPhosphorylation of MDMX mediated by Akt leads to stabilization and induces 14-3-3 bindingMechanistic differences in the transcriptional activation of p53 by 14-3-3 isoformsActivity of TSC2 is inhibited by AKT-mediated phosphorylation and membrane partitioningProtein kinase A-mediated 14-3-3 association impedes human Dapper1 to promote dishevelled degradationHypoxic tumor cell modulates its microenvironment to enhance angiogenic and metastatic potential by secretion of proteins and exosomesPhosphorylation-dependent regulation of cytosolic localization and oncogenic function of Skp2 by Akt/PKBInduction of cullin 7 by DNA damage attenuates p53 functionCpG island promoter methylation and silencing of 14-3-3sigma gene expression in LNCaP and Tramp-C1 prostate cancer cell lines is associated with methyl-CpG-binding protein MBD2An Omics Perspective on Molecular Biomarkers for Diagnosis, Prognosis, and Therapeutics of CholangiocarcinomaInvolvement of 14-3-3 Proteins in Regulating Tumor Progression of Hepatocellular CarcinomaApplicability of superfolder YFP bimolecular fluorescence complementation in vitroIdentification and structure of small-molecule stabilizers of 14-3-3 protein-protein interactionsStructure of a 14-3-3σ–YAP phosphopeptide complex at 1.15 Å resolutionAn optimised small-molecule stabiliser of the 14-3-3-PMA2 protein-protein interactionMolecular tweezers modulate 14-3-3 protein-protein interactionsChibby cooperates with 14-3-3 to regulate beta-catenin subcellular distribution and signaling activityThe role of epigenetic inactivation of 14-3-3sigma in human cancerThree-way interaction between 14-3-3 proteins, the N-terminal region of tyrosine hydroxylase, and negatively charged membranesRole of DLC1 tumor suppressor gene and MYC oncogene in pathogenesis of human hepatocellular carcinoma: potential prospects for combined targeted therapeutics (review)Isoform- and subcellular fraction-specific differences in hippocampal 14-3-3 levels following experimentally evoked seizures and in human temporal lobe epilepsy14-3-3 proteins play a role in the cell cycle by shielding cdt2 from ubiquitin-mediated degradationPI 3-kinase-dependent phosphorylation of Plk1-Ser99 promotes association with 14-3-3γ and is required for metaphase-anaphase transition.Prostate cancer is characterized by epigenetic silencing of 14-3-3sigma expression.Bcl-x(L)-mediated changes in metabolic pathways of breast cancer cells: from survival in the blood stream to organ-specific metastasis.Aberrant overexpression of an epithelial marker, 14-3-3sigma, in a subset of hematological malignanciesCooperative effect of p21Cip1/WAF-1 and 14-3-3sigma on cell cycle arrest and apoptosis induction by p14ARF.14-3-3sigma Modulates pancreatic cancer cell survival and invasivenessDifferential tissue-specific protein markers of vaginal carcinoma.Novel snail1 target proteins in human colon cancer identified by proteomic analysis.14-3-3gamma induces oncogenic transformation by stimulating MAP kinase and PI3K signaling.Identification of a suppressive mechanism for Hedgehog signaling through a novel interaction of Gli with 14-3-3.14-3-3 zeta is a molecular target in guggulsterone induced apoptosis in head and neck cancer cells.14-3-3σ induces heat shock protein 70 expression in hepatocellular carcinoma.
P2860
Q21256648-3BEED81D-9B52-493E-8270-A98159CB7FFFQ24294250-4C4275A7-A3B7-442E-8D2B-2ECAE6A3D41FQ24298526-5CDFB142-2514-4B13-B920-46FE898097F9Q24299077-0FA70D7A-633C-4386-A123-4109AE723001Q24301742-3D3A5A3C-25A5-47F4-80F7-94936EF28F25Q24306287-5C56C38A-72B5-4B2B-8D78-7BB29A7EDCECQ24310237-250017B6-8073-42DE-807D-F9F589F5FC69Q24313228-51C51E0D-CD06-4256-9DD6-53BD5ECB3278Q24319736-AF6520E1-FF97-448E-B82C-5C73FEDD97ECQ24320102-B3A40430-0009-4666-921D-CCE027AE8790Q24338245-4947577D-2364-470D-AEBE-B97A5D630533Q24604279-C91D423F-F7BA-4860-9BB3-701A4910410CQ24634406-5EF685A1-23E8-4806-9915-4BFCF1573A64Q24675258-0D9848CE-11B0-4FB3-B985-DEB1062A5851Q24684224-366FA0A1-5A4F-461D-B225-92C988DF42A7Q26784091-ABD8C0BD-F380-44DB-BAEB-209D9F9F7E61Q27001182-8556570E-8F0C-4275-9E5E-881DE892D968Q27652896-3EEA79E4-F151-4610-97C1-FD69C1CAA7EEQ27661215-A51D41EC-A8D6-4265-BBA6-0D4A8901D391Q27664315-D2F8D9F5-F95B-49C2-9206-699FFF16094FQ27678285-2D890253-1804-41BD-AB6D-5EE978937555Q27684041-28E2D3B2-C316-4A27-B51E-847693E10E03Q28114807-7F7DF6D2-E992-4F97-A561-F0584D4D2538Q28247253-65098117-DD9D-49C4-8EFF-C53E4FBD7D66Q28260366-6AAAD985-92A5-4C7F-BF57-49B168BB86BEQ28394917-B7B7FDA6-E83C-4BCA-9232-609580C34E93Q28579247-E52AE1A3-37FB-4511-BB88-19023AD150BDQ30405556-8EF74170-136B-4942-9662-B1F2D93348BBQ30540402-A53B07A4-B468-4950-A903-1454399D1767Q30769366-7DC69CEF-931C-4C02-A9D4-F83F65DBF4CAQ33224181-4EC6A2AB-269C-4A79-99D5-E7D659E1D2E8Q33307070-42433346-2B37-4AD4-A949-D124ACC2CD2CQ33370904-B038AAC5-EA83-4FC2-A360-03A2514BAC21Q33388611-15C472B4-F40B-434A-A213-715D01F38A57Q33430245-5A1F952A-915D-4334-BF53-710B5D92C2C9Q33565347-33ACECD2-B7ED-4399-A7BE-438B3FC6640BQ33632327-68E98FF8-069B-495B-AF88-6B74131B93A9Q33662376-688BE1D5-62BF-4C47-A8F9-4E0A43B77D1CQ33758993-DB9D09D9-D32F-4C67-A92E-7F085BBE5728Q33769256-1CC48E13-B624-4540-A2B1-6B68A48A4AF8
P2860
description
2003 nî lūn-bûn
@nan
2003年の論文
@ja
2003年論文
@yue
2003年論文
@zh-hant
2003年論文
@zh-hk
2003年論文
@zh-mo
2003年論文
@zh-tw
2003年论文
@wuu
2003年论文
@zh
2003年论文
@zh-cn
name
The 14-3-3 cancer connection.
@ast
The 14-3-3 cancer connection.
@en
type
label
The 14-3-3 cancer connection.
@ast
The 14-3-3 cancer connection.
@en
prefLabel
The 14-3-3 cancer connection.
@ast
The 14-3-3 cancer connection.
@en
P356
P1476
The 14-3-3 cancer connection.
@en
P2093
Heiko Hermeking
P2888
P304
P356
10.1038/NRC1230
P407
P577
2003-12-01T00:00:00Z