Adenovirus infection triggers a rapid, MyD88-regulated transcriptome response critical to acute-phase and adaptive immune responses in vivo - Wikidata - awgldk - TriplyDB

Adenovirus infection triggers a rapid, MyD88-regulated transcriptome response critical to acute-phase and adaptive immune responses in vivo

Adenovirus infection triggers a rapid, MyD88-regulated transcriptome response critical to acute-phase and adaptive immune responses in vivo

http://www.wikidata.org/entity/Q35635396

about

SAMHD1-Dependent and -Independent Functions of HIV-2/SIV Vpx Protein SAMHD1 is a nucleic-acid binding protein that is mislocalized due to aicardi-goutières syndrome-associated mutations Mutations involved in Aicardi-Goutières syndrome implicate SAMHD1 as regulator of the innate immune response Aicardi-Goutieres syndrome and related phenotypes: linking nucleic acid metabolism with autoimmunity A 4-year-old Amish boy with weakness, arthritis, rash, verbal delay, and failure to thrive TRIF is a critical negative regulator of TLR agonist mediated activation of dendritic cells in vivo Toll-Like Receptors and Viruses: Induction of Innate Antiviral Immune Responses Vaccine platforms combining circumsporozoite protein and potent immune modulators, rEA or EAT-2, paradoxically result in opposing immune responses Mechanisms of pathogenesis of emerging adenoviruses.Complex interactions with several arms of the complement system dictate innate and humoral immunity to adenoviral vectors.Transient pretreatment with glucocorticoid ablates innate toxicity of systemically delivered adenoviral vectors without reducing efficacy.Adenovirus capsid-display of the retro-oriented human complement inhibitor DAF reduces Ad vector-triggered immune responses in vitro and in vivo.Genetics, recombination and clinical features of human rhinovirus species C (HRV-C) infections; interactions of HRV-C with other respiratory viruses Fusion of HCV nonstructural antigen to MHC class II-associated invariant chain enhances T-cell responses induced by vectored vaccines in nonhuman primates.CR1/2 is an important suppressor of Adenovirus-induced innate immune responses and is required for induction of neutralizing antibodies CDK9 inhibition strategy defines distinct sets of target genes.The early activation of CD8+ T cells is dependent on type I IFN signaling following intramuscular vaccination of adenovirus vector.TRIF, and TRIF-interacting TLRs differentially modulate several adenovirus vector-induced immune responses.Innate immune recognition of viruses and viral vectors.MyD88-dependent silencing of transgene expression during the innate and adaptive immune response to helper-dependent adenovirus.beta-Arrestins modulate Adenovirus-vector-induced innate immune responses: differential regulation by beta-arrestin-1 and beta-arrestin-2.Novel adenovirus vectors 'capsid-displaying' a human complement inhibitor.Recognition of virus infection and innate host responses to viral gene therapy vectors.Evaluation of innate immunity and vector toxicity following inoculation of bovine, porcine or human adenoviral vectors in a mouse model Ligand-independent toll-like receptor signals generated by ectopic overexpression of MyD88 generate local and systemic antitumor immunity Nuclease activity of the human SAMHD1 protein implicated in the Aicardi-Goutieres syndrome and HIV-1 restriction.Selectivity of oncolytic viral replication prevents antiviral immune response and toxicity, but does not improve antitumoral immunity.The human adenovirus type 5 E1B 55 kDa protein obstructs inhibition of viral replication by type I interferon in normal human cells.Multiple innate immune pathways contribute to the immunogenicity of recombinant adenovirus vaccine vectors Unabated adenovirus replication following activation of the cGAS/STING-dependent antiviral response in human cells.Delivery route, MyD88 signaling and cross-priming events determine the anti-tumor efficacy of an adenovirus based melanoma vaccine.Adenovirus vector induced innate immune responses: impact upon efficacy and toxicity in gene therapy and vaccine applications.Homozygous mutation in SAMHD1 gene causes cerebral vasculopathy and early onset stroke An inducible transgenic mouse model for immune mediated hepatitis showing clearance of antigen expressing hepatocytes by CD8+ T cells Helper-dependent adenoviral vectors for liver-directed gene therapy.Adenovirus type 5 induces vitamin A-metabolizing enzymes in dendritic cells and enhances priming of gut-homing CD8 T cells.MyD88-dependent protective immunity elicited by adenovirus 5 expressing the surface antigen 1 from Toxoplasma gondii is mediated by CD8(+) T lymphocytes.In vivo and in vitro characterization of the immune stimulating activity of the Neisserial porin PorB Antigen expression determines adenoviral vaccine potency independent of IFN and STING signaling.High persistence rate of hepatitis B virus in a hydrodynamic injection-based transfection model in C3H/HeN mice.

P2860

Q21131138-F397AA58-FF7B-43ED-B8AD-E7E3F2F086F5 Q24310328-ED98F5A7-A39D-481A-8CC8-781E44D87B65 Q24338296-62B2A13D-6753-4B9F-86D6-FB5979D73762 Q24655886-B0339509-E021-4C2D-838F-E1390CB5583C Q26995545-0D9CE8DF-B45D-41A4-A5A6-64F6260EC558 Q27332276-35B6D2D6-09BC-4FD2-9214-4F20AC32D2D9 Q27487393-CD409EDD-B0AC-47F1-9307-F3903335E009 Q28740832-E52D09A6-2471-4B2D-B995-BF7EBDA96D69 Q30238495-2994F59A-E681-4E1B-8AAC-0B812102EBBD Q33380283-A7CF87F2-F585-47E2-A624-50F2D2B890A9 Q33382953-AF8CD8FC-DBA1-45F2-9E4F-24B32B37C532 Q33389860-620E0BC0-5AB1-461D-914E-78104EFBD029 Q33521243-3DC30576-49C4-4969-8C3B-9DEB6DF6F464 Q33586992-E3E155DD-02A8-4B58-8A04-1BC50CA973DD Q33687979-27255D06-F2E5-49E5-B2CF-BFE038C1DA01 Q33712529-0F247A75-A603-4DD3-AF56-9B605D368375 Q33757762-F700DD03-11AD-4D55-AF7B-AC4EFA8D43F3 Q33785096-7F2B43D9-04DD-4A61-BE82-4EA2981D7847 Q33805229-B29DFB03-B739-468D-BCB2-8EA38CF51C7F Q33832157-8DA3DEF6-A0B2-47BC-B37D-2F7AC793DE78 Q33915868-4FB20988-0B10-426E-9A8D-C408B677084D Q33955918-5B0A02F8-6BB1-4C43-9A2F-7C0E90F66EB7 Q34080884-F4413ED4-0884-4725-8038-FB4EF14411EA Q34153735-2B884CEE-0411-4346-B4B7-B3126B7FDAAC Q34153811-592080FB-F8DD-4803-AF97-4A716DD5A924 Q34325381-04EB73A4-A275-41B7-BC7D-0A293D71B179 Q34343742-B054323A-4FCB-492C-9357-04053F2217AB Q34388476-2B70DBB5-4FEF-43D2-9D0F-2CB64934CE3D Q34457800-8FBDE13E-2F1E-44C1-B01F-D00E86D89592 Q34594959-7401272F-4659-4B92-8C0D-29D8DA7134A2 Q34677842-3A472ABB-8168-4791-A91D-F0D769A77334 Q34717992-5DC9C5C0-D6EA-4B60-B645-BB73A91A74AA Q34750121-FEAE1A66-F287-46B4-ADBD-0F2E9D0A15DA Q34837899-5A84E6A7-6A5B-4D59-B437-DE9B529E4383 Q34982825-A2528172-C959-4FE8-A60B-223E81BCEC4B Q34990401-FF6987E6-757B-4233-83E4-53D639DAF0DE Q35046630-06798226-B522-467F-8F44-F6056CF541A0 Q35070034-2AB47AAE-B5FB-4B4B-A979-D60A5A5AF2FF Q35183935-455EF5C3-71E8-470E-B7DE-EDD61B651CA6 Q35221786-634FCC34-4F01-4B2B-A6AB-143E5058D1B4

P2860

Adenovirus infection triggers a rapid, MyD88-regulated transcriptome response critical to acute-phase and adaptive immune responses in vivo

http://www.wikidata.org/entity/Q35635396

description

2006 nî lūn-bûn

@nan

2006年の論文

@ja

2006年論文

@yue

2006年論文

@zh-hant

2006年論文

@zh-hk

2006年論文

@zh-mo

2006年論文

@zh-tw

2006年论文

@wuu

2006年论文

@zh

2006年论文

@zh-cn

name

Adenovirus infection triggers ...... ptive immune responses in vivo

@ast

Adenovirus infection triggers ...... ptive immune responses in vivo

@en

type

label

Adenovirus infection triggers ...... ptive immune responses in vivo

@ast

Adenovirus infection triggers ...... ptive immune responses in vivo

@en

prefLabel

Adenovirus infection triggers ...... ptive immune responses in vivo

@ast

Adenovirus infection triggers ...... ptive immune responses in vivo

@en

P1433

Q35635396-141196B2-E946-432B-AFC8-B159ED795A0F

P1476

Q35635396-8D8AC3BC-BE15-47B4-8DBC-AC7119EBF347

P2093

Q35635396-300567A6-C6F6-4338-B43B-4230760B4382

Q35635396-33DCEDDD-B519-4287-80E3-61A73C05271B

Q35635396-8DE62EEF-0498-4359-B7C7-2E967152F2A9

Q35635396-C96E0E19-E87D-44C9-9128-ED6FB28E71AC

Q35635396-E6873A9F-E0DE-481F-8813-235B34794B37

Q35635396-F2B15E68-77AD-4A55-8D6C-FFEEDE27F2A5

P2860

Q35635396-047C5CA2-33FA-4229-8451-8229564CB5BD

Q35635396-08A7E361-EDDE-4483-B4D6-F5B2B0B47740

Q35635396-0A7BAB13-13ED-485F-AA3A-C36A0230C359

Q35635396-124F91CC-237A-49D7-9E60-BEAE601F8DC9

Q35635396-23363DCE-4D90-4DCF-ADAA-26D93723D617

Q35635396-24063405-CF15-45B8-9F7D-AD1EAA7322DA

Q35635396-256EB5AE-C7C0-43ED-A82D-1EF5649E2A2E

Q35635396-27D3D0F1-034A-470C-B80B-A06E928D985B

Q35635396-2AF28CB4-F56C-4ABF-93A6-52F211293853

Q35635396-34DBE331-5122-493B-88BB-A636E18070B0

P304

Q35635396-A8E56F58-54B0-466D-B612-5122FCF09415

P31

Q35635396-83C7010B-5738-4148-AE00-E5A056072A89

P356

Q35635396-8BABF8E4-4D4D-4E4D-8325-96CE8CFB811D

P407

Q35635396-C1A6DBC1-D722-4FB0-874F-3D860BA402E2

P433

Q35635396-65C283E4-D3AE-467F-A410-F94B9822643E

P478

Q35635396-5173DBF2-1B66-4469-89E2-F704B350A00E

P50

Q35635396-F02D4496-A9E8-4E40-B860-E14412CBA8A7

P577

Q35635396-96F96F1A-2F36-404A-BCFA-BB1B4A42526B

P698

Q35635396-41B04563-5BED-426A-9FA0-04CE66FA29C9

P921

Q35635396-5AED0A44-5079-4107-A073-5ACDDFA9E477

Q35635396-B40B890C-648A-4A8A-9892-B10A0EB25043

P932

Q35635396-BBDB3453-2974-4610-AC4A-6431C6B1FB60

P356

P1433

Journal of Virology

P1476

Adenovirus infection triggers ...... ptive immune responses in vivo

@en

P2093

Andrea Amalfitano

http://www.w3.org/2001/XMLSchema#string

Anne Kiang

http://www.w3.org/2001/XMLSchema#string

Delila Serra

http://www.w3.org/2001/XMLSchema#string

Timothy M Clay

http://www.w3.org/2001/XMLSchema#string

Xiao Y Yang

http://www.w3.org/2001/XMLSchema#string

Zachary C Hartman

http://www.w3.org/2001/XMLSchema#string

P2860

IPS-1, an adaptor triggering RIG-I- and Mda5-mediated type I interferon induction

Accurate normalization of real-time quantitative RT-PCR data by geometric averaging of multiple internal control genes

Identifying biological themes within lists of genes with EASE

GOTree Machine (GOTM): a web-based platform for interpreting sets of interesting genes using Gene Ontology hierarchies

Impact of cryopreservation on tetramer, cytokine flow cytometry, and ELISPOT

Analysis of Relative Gene Expression Data Using Real-Time Quantitative PCR and the 2−ΔΔCT Method

Identification and characterization of MAVS, a mitochondrial antiviral signaling protein that activates NF-kappaB and IRF 3

A human homologue of the Drosophila Toll protein signals activation of adaptive immunity

VISA is an adapter protein required for virus-triggered IFN-beta signaling

Targeted disruption of the MyD88 gene results in loss of IL-1- and IL-18-mediated function

P304

1796-1812

http://www.w3.org/2001/XMLSchema#string

P31

scholarly article

P356

10.1128/JVI.01936-06

http://www.w3.org/2001/XMLSchema#string

P407

P433

4

http://www.w3.org/2001/XMLSchema#string

P478

81

http://www.w3.org/2001/XMLSchema#string

P50

P577

2006-11-22T00:00:00Z

http://www.w3.org/2001/XMLSchema#dateTime

P698

17121790

http://www.w3.org/2001/XMLSchema#string

P921

P932

1797572

http://www.w3.org/2001/XMLSchema#string